ES8802051A1 - Un metodo para preparar derivados de 9-bencilpurina - Google Patents
Un metodo para preparar derivados de 9-bencilpurinaInfo
- Publication number
- ES8802051A1 ES8802051A1 ES550466A ES550466A ES8802051A1 ES 8802051 A1 ES8802051 A1 ES 8802051A1 ES 550466 A ES550466 A ES 550466A ES 550466 A ES550466 A ES 550466A ES 8802051 A1 ES8802051 A1 ES 8802051A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- hydrogen
- ethyl
- methyl
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 9-BENCILPURINA, DE FORMULA (I), Y DE SUS SALES DE ADICION DE ACIDO. COMPRENDE LA REACCION DE SUSTITUCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER UN COMPUESTO DE FORMULA (I), EN EL QUE R7 ES HIDROGENO O FLUOR, X REPRESENTA UN HALOGENO, Y R5 Y R6 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE EFECTUA EN UN DISOLVENTE APROTICO DIPOLAR, EN PRESENCIA DE UNA BASE A UNA TEMPERATURA COMPRENDIDA ENTRE 50JC Y 100JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848408615A GB8408615D0 (en) | 1984-04-04 | 1984-04-04 | Heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES550466A0 ES550466A0 (es) | 1987-03-01 |
| ES8802051A1 true ES8802051A1 (es) | 1987-03-01 |
Family
ID=10559131
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541948A Expired ES8606348A1 (es) | 1984-04-04 | 1985-04-03 | Un metodo para preparar un derivado de 9-bencilpurina |
| ES550467A Expired ES8802052A1 (es) | 1984-04-04 | 1985-12-27 | Un metodo para preparar derivados de 9-bencilpurina |
| ES550466A Expired ES8802051A1 (es) | 1984-04-04 | 1985-12-27 | Un metodo para preparar derivados de 9-bencilpurina |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541948A Expired ES8606348A1 (es) | 1984-04-04 | 1985-04-03 | Un metodo para preparar un derivado de 9-bencilpurina |
| ES550467A Expired ES8802052A1 (es) | 1984-04-04 | 1985-12-27 | Un metodo para preparar derivados de 9-bencilpurina |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0157637A3 (es) |
| JP (1) | JPS60226880A (es) |
| AU (1) | AU4081185A (es) |
| DD (1) | DD233843A5 (es) |
| DK (1) | DK147285A (es) |
| ES (3) | ES8606348A1 (es) |
| FI (1) | FI851351L (es) |
| GB (1) | GB8408615D0 (es) |
| GR (1) | GR850838B (es) |
| HU (1) | HUT37429A (es) |
| IL (1) | IL74803A0 (es) |
| PL (1) | PL252743A1 (es) |
| ZA (1) | ZA852534B (es) |
| ZW (1) | ZW6785A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204353A (en) * | 1987-04-07 | 1993-04-20 | Ciba-Geigy Corporation | 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith |
| EP0363320A3 (de) * | 1988-10-06 | 1991-11-21 | Ciba-Geigy Ag | Substituierte 9H-Purine |
| US5166209A (en) * | 1989-04-21 | 1992-11-24 | Burroughs Wellcome Co. | Pharmacologically active compounds |
| GB8913011D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Anticonvulsant pyrazines |
| US5240937A (en) * | 1990-04-20 | 1993-08-31 | Burroughs Wellcome Co. | Pharmaceutically active triazolopyridine compounds |
| US6992188B1 (en) | 1995-12-08 | 2006-01-31 | Pfizer, Inc. | Substituted heterocyclic derivatives |
| DK0778277T3 (da) * | 1995-12-08 | 2003-10-27 | Pfizer | Substituerede heterocycliske derivater som CRF antagonister |
| US6107300A (en) * | 1996-03-27 | 2000-08-22 | Dupont Pharmaceuticals | Arylamino fused pyrimidines |
| US6648453B2 (en) | 1997-07-15 | 2003-11-18 | Silverbrook Research Pty Ltd | Ink jet printhead chip with predetermined micro-electromechanical systems height |
| US20230279006A1 (en) * | 2020-07-08 | 2023-09-07 | Klotho Therapeutics, Inc. | Novel compounds and methods for increasing klotho gene expression |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3846426A (en) * | 1971-03-03 | 1974-11-05 | Int Minerals & Chem Corp | 6-amino-9-(substituted benzyl) purines and their n{11 oxides |
| US3862189A (en) * | 1973-08-14 | 1975-01-21 | Warner Lambert Co | Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents |
| GB1547214A (en) * | 1977-08-09 | 1979-06-06 | Merck & Co Inc | Purine derivatives |
| US4189485A (en) * | 1977-08-23 | 1980-02-19 | Takeda Chemical Industries, Ltd. | Purine derivatives |
| US4900826A (en) * | 1981-09-24 | 1990-02-13 | Kohjin Co., Ltd. | Process for preparing N6,9-disubstituted adenine |
-
1984
- 1984-04-04 GB GB848408615A patent/GB8408615D0/en active Pending
-
1985
- 1985-04-01 DK DK147285A patent/DK147285A/da not_active IP Right Cessation
- 1985-04-02 EP EP85302321A patent/EP0157637A3/en not_active Withdrawn
- 1985-04-03 PL PL25274385A patent/PL252743A1/xx unknown
- 1985-04-03 ES ES541948A patent/ES8606348A1/es not_active Expired
- 1985-04-03 GR GR850838A patent/GR850838B/el unknown
- 1985-04-03 HU HU851270A patent/HUT37429A/hu unknown
- 1985-04-03 ZA ZA852534A patent/ZA852534B/xx unknown
- 1985-04-03 DD DD85274834A patent/DD233843A5/de unknown
- 1985-04-03 JP JP60070739A patent/JPS60226880A/ja active Pending
- 1985-04-03 IL IL74803A patent/IL74803A0/xx unknown
- 1985-04-03 FI FI851351A patent/FI851351L/fi not_active Application Discontinuation
- 1985-04-03 ZW ZW67/85A patent/ZW6785A1/xx unknown
- 1985-04-03 AU AU40811/85A patent/AU4081185A/en not_active Abandoned
- 1985-12-27 ES ES550467A patent/ES8802052A1/es not_active Expired
- 1985-12-27 ES ES550466A patent/ES8802051A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI851351A0 (fi) | 1985-04-03 |
| EP0157637A3 (en) | 1986-11-05 |
| DK147285A (da) | 1985-10-05 |
| ES550467A0 (es) | 1987-03-01 |
| EP0157637A2 (en) | 1985-10-09 |
| ZA852534B (en) | 1986-11-26 |
| DK147285D0 (da) | 1985-04-01 |
| DD233843A5 (de) | 1986-03-12 |
| ES8802052A1 (es) | 1987-03-01 |
| GB8408615D0 (en) | 1984-05-16 |
| AU4081185A (en) | 1985-10-10 |
| PL252743A1 (en) | 1986-09-09 |
| ES8606348A1 (es) | 1986-04-16 |
| FI851351L (fi) | 1985-10-05 |
| ZW6785A1 (en) | 1986-11-12 |
| JPS60226880A (ja) | 1985-11-12 |
| GR850838B (es) | 1985-11-25 |
| IL74803A0 (en) | 1985-07-31 |
| ES550466A0 (es) | 1987-03-01 |
| ES541948A0 (es) | 1986-04-16 |
| HUT37429A (en) | 1985-12-28 |
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