GB2106105B - Benzo-heterocycles - Google Patents

Benzo-heterocycles

Info

Publication number
GB2106105B
GB2106105B GB08224810A GB8224810A GB2106105B GB 2106105 B GB2106105 B GB 2106105B GB 08224810 A GB08224810 A GB 08224810A GB 8224810 A GB8224810 A GB 8224810A GB 2106105 B GB2106105 B GB 2106105B
Authority
GB
United Kingdom
Prior art keywords
heterocycles
benzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08224810A
Other languages
English (en)
Other versions
GB2106105A (en
Inventor
Armin Fugner
Ernst-Otto Renth
Anton Mentrup
Kurt Schromm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of GB2106105A publication Critical patent/GB2106105A/en
Application granted granted Critical
Publication of GB2106105B publication Critical patent/GB2106105B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB08224810A 1981-09-01 1982-08-31 Benzo-heterocycles Expired GB2106105B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813134590 DE3134590A1 (de) 1981-09-01 1981-09-01 Neue benzo-heterocyclen

Publications (2)

Publication Number Publication Date
GB2106105A GB2106105A (en) 1983-04-07
GB2106105B true GB2106105B (en) 1985-07-10

Family

ID=6140603

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08224810A Expired GB2106105B (en) 1981-09-01 1982-08-31 Benzo-heterocycles

Country Status (25)

Country Link
EP (1) EP0073505B1 (enExample)
JP (1) JPS5852278A (enExample)
KR (1) KR890000380B1 (enExample)
AR (2) AR231976A1 (enExample)
AT (1) ATE16703T1 (enExample)
AU (1) AU553589B2 (enExample)
CA (1) CA1180012A (enExample)
CS (1) CS236679B2 (enExample)
DD (1) DD204477A5 (enExample)
DE (2) DE3134590A1 (enExample)
DK (1) DK158664C (enExample)
ES (3) ES515380A0 (enExample)
FI (1) FI78475C (enExample)
GB (1) GB2106105B (enExample)
GR (1) GR77275B (enExample)
HU (1) HU186112B (enExample)
IE (1) IE53615B1 (enExample)
IL (1) IL66683A0 (enExample)
NO (1) NO157738C (enExample)
NZ (1) NZ201777A (enExample)
PL (1) PL139375B1 (enExample)
PT (1) PT75478A (enExample)
SU (1) SU1149876A3 (enExample)
YU (1) YU42794B (enExample)
ZA (1) ZA826349B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD474664S1 (en) 2002-04-30 2003-05-20 Trudeau Corporation 1889 Inc. Corkscrew

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
DE3743265A1 (de) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg Neue ammoniumverbindungen, ihre herstellung und verwendung
TW372967B (en) * 1994-12-27 1999-11-01 Kanebo Ltd 1,4 benzoxazine derivative, pharmaceutical composition containing the same and use thereof
DE10253282A1 (de) * 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
PT1613315E (pt) * 2003-04-04 2009-04-22 Novartis Ag Derivados da quinolina-2-ona para o tratamento de doenças das vias aéreas respiratórias
GB0307856D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
US7307076B2 (en) 2004-05-13 2007-12-11 Boehringer Ingelheim International Gmbh Beta agonists for the treatment of respiratory diseases
EP1789394A1 (de) * 2004-05-13 2007-05-30 Boehringer Ingelheim International Gmbh Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen
DE102004024453A1 (de) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen
DE102004024452A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation von Betaagonisten
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024451A1 (de) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
AU2006281449B2 (en) * 2005-08-15 2013-01-31 Boehringer Ingelheim International Gmbh Method for producing betamimetics
TWI389692B (zh) 2005-10-10 2013-03-21 Boehringer Ingelheim Int 用以吸入β-共效劑的氣溶膠調配物
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
EP2057152A1 (de) * 2006-08-07 2009-05-13 Boehringer Ingelheim International GmbH Enantiomerenreine betaagonisten, verfahren zu deren herstellung und deren verwendung als arzneimittel
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
ATE518847T1 (de) * 2007-01-25 2011-08-15 Boehringer Ingelheim Int Verfahren zur herstellung von betamimetika

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (enExample) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
CA1041523A (en) * 1974-06-19 1978-10-31 Queen's University Preparation of 1-oxapenicillins and novel intermediates therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD474664S1 (en) 2002-04-30 2003-05-20 Trudeau Corporation 1889 Inc. Corkscrew

Also Published As

Publication number Publication date
KR890000380B1 (ko) 1989-03-15
CA1180012A (en) 1984-12-27
JPH035392B2 (enExample) 1991-01-25
AR231977A1 (es) 1985-04-30
NO157738B (no) 1988-02-01
HU186112B (en) 1985-06-28
ES8402279A1 (es) 1984-01-16
DD204477A5 (de) 1983-11-30
IE822105L (en) 1983-03-01
ES521871A0 (es) 1984-06-16
DK158664C (da) 1991-01-14
JPS5852278A (ja) 1983-03-28
DK389082A (da) 1983-03-02
AU553589B2 (en) 1986-07-24
DE3134590A1 (de) 1983-03-10
ES8308318A1 (es) 1983-08-16
AU8787482A (en) 1983-03-10
YU42794B (en) 1988-12-31
IL66683A0 (en) 1982-12-31
PL139375B1 (en) 1987-01-31
ES515380A0 (es) 1983-08-16
ATE16703T1 (de) 1985-12-15
FI822985L (fi) 1983-03-02
AR231976A1 (es) 1985-04-30
YU194982A (en) 1984-12-31
NZ201777A (en) 1985-08-30
SU1149876A3 (en) 1985-04-07
ES521870A0 (es) 1984-01-16
ES8405778A1 (es) 1984-06-16
NO157738C (no) 1988-05-11
CS236679B2 (en) 1985-05-15
FI78475B (fi) 1989-04-28
GR77275B (enExample) 1984-09-11
DE3267702D1 (en) 1986-01-09
GB2106105A (en) 1983-04-07
ZA826349B (en) 1984-04-25
IE53615B1 (en) 1988-12-21
KR840001560A (ko) 1984-05-07
EP0073505B1 (de) 1985-11-27
FI822985A0 (fi) 1982-08-30
EP0073505A1 (de) 1983-03-09
PT75478A (en) 1982-09-01
PL238077A1 (en) 1984-04-09
FI78475C (fi) 1989-08-10
DK158664B (da) 1990-07-02
NO822932L (no) 1983-03-02

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930831