KR880009900A - 살균제 - Google Patents

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KR880009900A
KR880009900A KR1019880001176A KR880001176A KR880009900A KR 880009900 A KR880009900 A KR 880009900A KR 1019880001176 A KR1019880001176 A KR 1019880001176A KR 880001176 A KR880001176 A KR 880001176A KR 880009900 A KR880009900 A KR 880009900A
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South Korea
Prior art keywords
compound
alkyl
formula
optionally substituted
alkoxy
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KR1019880001176A
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English (en)
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KR960013832B1 (ko
Inventor
마틴 클라우 존
리차드 에일스 고드프레이 크리스토퍼
존 드 프레인 파울
마가레트 앤토니 비비엔
고돈 헛칭스 미켈
Original Assignee
원본미기재
임페리알 케미칼 인더스트리스 피엘씨
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26291884&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR880009900(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878702845A external-priority patent/GB8702845D0/en
Priority claimed from GB878710594A external-priority patent/GB8710594D0/en
Application filed by 원본미기재, 임페리알 케미칼 인더스트리스 피엘씨 filed Critical 원본미기재
Publication of KR880009900A publication Critical patent/KR880009900A/ko
Priority to KR1019950045664A priority Critical patent/KR960005513B1/ko
Application granted granted Critical
Publication of KR960013832B1 publication Critical patent/KR960013832B1/ko

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    • C07ORGANIC CHEMISTRY
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    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
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    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
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    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
    • A01N37/40Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
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    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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    • A01N43/06Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
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    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
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    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A01N43/42Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
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    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/38Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. nitrodiphenyl ethers
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    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/28Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
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    • C07C69/736Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
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    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract

내용 없음.

Description

살균제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (24)

  1. 다음 구조식(Ⅰ)화합물 및 그것의 입체 이성체.
    식중, R1은 임의 치환 아릴 또는 임의 치환 헤테로아릴 Y는 산소, 황 또는 NR4; R2, R3및 R4는 같거나 다를수 있고 수소, C1-4.알킬 또는 C2-4알케닐: X는 할로겐, C1-4알킬, C2-4알케닐, C2-4알콕시, 니트로 또는 시아노: n은 0 또는 1-4: Y가 산소이고, n이 0이며 R1이 비치환 페닐일 때 R2및 R3의 최소 하나는 수소 또는 메틸이 아님.
  2. 제1항에 있어서, Y가 산소인 화합물.
  3. 제1항에 있어서, Y가 산소이고 R1이 치환된 페닐인 화합물.
  4. 제1항 또는 제2항에 있어서, R1이 임의 치환 헤테로아릴인 화합물.
  5. 제1항에 있어서, R1이 임의 치환 아릴이고 Y가 NR4인 화합물.
  6. 제1항에 있어서, Y가 NR4이고 R1이 전자를 잡아 당기는 그룹으로 치환된 화합물.
  7. 제1항에 있어서, R1이 임의 치환 아릴이고 Y가 산소 또는 황이며 R2및 R3둘다가 수소는 아닌 화합물.
  8. 제1항에 있어서, X가 C2-4알케닐인 화합물.
  9. 제1항 또는 제2항에 있어서, R1이 하나 이상의 하이드록시, C3-6사이클로알킬(C1-4)알킬, 아릴(C1-4)알콕시, 아릴옥시(C1-4)알킬, 아실옥시, CR=NR″또는 N=CR′R″로 임의 치환된 아릴이고 R′및 R″가 독립적으로 수소, C1-4알킬티오, C3-6사이클로알킬, C3-6사이클로알킬(C1-4)알킬, 페닐 또는 벤질이며 페닐 및 벤질 그룹이 할로겐, C1-4알킬 또는 C1-4알콕시로 임의 치환된 화합물.
  10. 제1항 또는 제2항에 있어서, R1이 하나 이상의 NR′R″, NHCOR′, NHCONR′R″, CO2R′, OSO2R′SO2R′ 또는 COR′로 임의 치환된 아릴이고 R′가 C3-6사이클로알킬(C1-4)알킬 또는 벤질이며 R″가 수소, C1-4알킬티오, C3-6사이클로알킬, C3-6사이클로알킬(C1-4)알킬, 페닐 또는 벤질이고 페닐 및 벤질 그룹이 할로겐, C1-4알킬 또는 C1-4알킬 또는 C1-4알콕시로 임의 치환된 화합물.
  11. 다음 구조식(Ia) 화합물의(E)-이성체.
    식중, Ab는 2-브로모:3-요오도:2-에틸:3-이소-프로필:3-드-부틸:3-트리플루오로메톡시:3-아미노:4-페닐:2-카복시:3메톡시카보닐:2-하이드록시:2,2-디플루오로:3,5-디플루오로:2,3-디메톡시:2-플루오로-4-클로로:2-클로로-5-플루오로:2-플루오로-6-메틸:3-메틸-4-플루오로:3-플루오로-5-메톡시:2-메톡시-3-플루오로:2-클로로-4-메틸:2-메틸-5-클로로:2-클로로-6메톡시:3-메톡시-4-클로로:3-메틸-5-메톡시:플루오로:2,4,6-트리클로로:2,4,6-트리메틸:2,6-디메틸-4-플루오로:2,3,5,6-테트라클로로:펜타플루오로: 및 펜타클로로로 구성되는 그룹으로부터 선택됨.
  12. 다음 구조식(Ib)화합물의 (E)-이성체.
    식중, Y는 제1항에 주어진 정의를 가지며, m은 1-5이고, A는 할로, 하이드록시, C1-4알킬, 할로(C1-4)알킬,C1-4알콕시, 할로(C1-4)알콕시, 페닐, 페녹시, 니트로, 아미노, 아실아미노, 시아노, 카복시, C1-4알콕시카보닐 또는 C1-4알킬카보닐옥시임.
  13. 다음 구조식(Ic)화합물.
    식중, B는 N 또는 CH이고: Y는 제1항에 주어진 정의를 가지며, P는 B가 N일때 0또는 1-3이거나 B가 CH일 때 0또는 1-4이며, A1은 제12항의 A의 정의를 가짐
  14. 제13항에 있어서, Y가 환의 질소원자에 대해 오르토 위치에 부착되거나 치환체 A1이 환의 질소 원자에 대해 오르토 위치에 부착되거나 두 경우 다인 화합물.
  15. 다음 구조식(Id)화합물의 (E)-이성체.
    식중, q는 0 또는 1-5: D는 할로, 하이드록시, C1-4알킬, 할로(C1-4)알킬, C1-4알콕시, 할로(C1-4)알콕시 또는 페녹시: E는 수소 또는 할로겐.
  16. 다음 구조식(Ie)화합물의 (E)-이성체.
    식중, B는 N 또는 CH이고, r은 B가 N일때 0 또는 1-4이며 D 및 E는 제15항에 정의된 바와 같음.
  17. 다음 구조식(IF) 화합물의 (E)-이성체.
    식중, A는 3-브로모, 3-클로로 또는 4-클로로.
  18. (a) 다음 구조식(Ⅱ) 화합물을
    구조식 CH3L 화합물로 처리하거나 (b) 산성 또는 염기성 조건하에서 다음 구조식(IV) 화합물로부터 메탄올을 제거하거나
    (c)다음 구조식(Ⅵ)케토에스테르를
    메톡시메틸렌화 시약으로 처리하거나 (d) 다음 구조식(X) 화합물을
    구조식 R1YM 화합물로 처리하거나 (e) 염기의 존재에서 다음 구조식(ⅩⅢ)화합물을 화합물 R1L로 처리하거나
    (f) Y가 NR4일 때 다음 구조식(ⅩⅦ)의 아미드를 환원시키거나
    다음 구조식(ⅩⅦ)의 카보닐 화합물을 구조식 R1R4NH의 1차 아민 또는 2차 아민 및 적당한 환원제로 처리하는
    식중, R1, R2, R3, R4, Y, X 및 n은 제1항에 주어진 정의를 가지며, R5및 M은 금속 원자이고, L은 이탈 그룹이며 W는 그룹 CH3O.OCH:C(CO2CH3)로 전환될 수 있는 그룹임 것으로 구성되는, 제1항 화합물의 제조방법.
  19. 본 원에 정의된 바와 같은 구조식(II)-(VI) 및 (VIII)인 중간 생성 화합물.
  20. 다음 구조식(Ig)화합물.
    식중, T는 하이드록시, 머캅토, 포트밀, 하이드록시메틸, 클로로메틸, 브로모메틸, 아미노, 카복시 또는 R이 수소, 알킬 또는 아릴인 -CH2NHR임
  21. 다음 구조식(Ih) 화합물.
    〔식중, Q는 클로로메틸 또는 포르밀
  22. 다음 구조식 (Ⅸ)의 이소크로마논을 구조식 R1YM 화합물로 처리하는 것으로 구성되는, 제19항의 중간생성 화합물(Ⅷ)의 제조방법.
    식중, R1, R2, R3, Y, X 및 n은 제1항에 주어진 정의를 가지며 M은 금속 원자임.
  23. 제1항 내지 제19항의 어느 한 항 화합물의 살균적 효과량 및 살균적으로 허용 가능한 담체 또는 희석제로 구성되는 살균 조성물.
  24. 제1항 내지 제17항의 어느 한 항 화합물 또는 제23항 조성물을 식물에, 식물에 씨에, 또는 식물 또는 씨의 소재지에 사용하는 것으로 구성되는, 균류의 퇴치방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880001176A 1987-02-09 1988-02-09 살균제 KR960013832B1 (ko)

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GB2201152A (en) 1988-08-24
HU204166B (en) 1991-12-30
KR960013832B1 (ko) 1996-10-10
DE3875748T2 (de) 1993-03-25
NZ223234A (en) 1990-01-29
AU1066088A (en) 1988-08-11
EP0472224A1 (en) 1992-02-26
SA98190697A (ar) 2005-12-03
EG19678A (en) 1995-09-30
DK66888D0 (da) 1988-02-09
ES2053258T3 (es) 1994-07-16
ATE82268T1 (de) 1992-11-15
IL98741A0 (en) 1992-07-15
JP2559130B2 (ja) 1996-12-04
DK66888A (da) 1988-08-10
IL98742A0 (en) 1992-07-15
IE60730B1 (en) 1994-08-10
HUT46510A (en) 1988-11-28
DE3875748D1 (de) 1992-12-17
DK173360B3 (da) 2009-07-27
DE3889345T2 (de) 1994-09-01
NL350013I2 (nl) 2003-09-01
GB2201152B (en) 1991-08-14
US5021581A (en) 1991-06-04
DK199900354A (da) 1999-03-12
IE880124L (en) 1988-08-09
GB8800827D0 (en) 1988-02-17
EP0278595A2 (en) 1988-08-17
LU91196I2 (fr) 2005-10-31
IL98743A0 (en) 1992-07-15
US5438059A (en) 1995-08-01
GR3033171T3 (en) 2000-08-31
GR3006323T3 (ko) 1993-06-21
IL85122A (en) 1994-12-29
DK173360B1 (da) 2000-08-14
BR8800503A (pt) 1988-09-27
EP0278595A3 (en) 1989-04-05
JPH092906A (ja) 1997-01-07
DE3889345D1 (de) 1994-06-01
DE3875748T3 (de) 2000-08-31
ES2052696T5 (es) 2000-03-01
US6653258B1 (en) 2003-11-25
EP0278595B2 (en) 2000-01-12
ATE104948T1 (de) 1994-05-15
NL350013I1 (nl) 2003-08-01
ES2052696T3 (es) 1994-07-16
JP2904476B2 (ja) 1999-06-14
EP0472224B1 (en) 1994-04-27
EP0278595B1 (en) 1992-11-11
JPS63216848A (ja) 1988-09-09
AU615890B2 (en) 1991-10-17

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