KR880001104B1 - 구아니디노시클로헥산카복실산 유도체의 제조방법 - Google Patents

구아니디노시클로헥산카복실산 유도체의 제조방법

Info

Publication number
KR880001104B1
KR880001104B1 KR8200269A KR820000269A KR880001104B1 KR 880001104 B1 KR880001104 B1 KR 880001104B1 KR 8200269 A KR8200269 A KR 8200269A KR 820000269 A KR820000269 A KR 820000269A KR 880001104 B1 KR880001104 B1 KR 880001104B1
Authority
KR
South Korea
Prior art keywords
trans
hydrochloride
mixture
crystals
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR8200269A
Other languages
English (en)
Korean (ko)
Other versions
KR830009011A (ko
Inventor
마쯔 무쓰미 무라
도시오 사또오
히로야스 세끼네
아쓰 덴고
요시오 기가와
가나메 곤도오
Original Assignee
야마 구찌 아끼라
닛뽕 케미파 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP728481A external-priority patent/JPS57122061A/ja
Priority claimed from JP728681A external-priority patent/JPS57122060A/ja
Priority claimed from JP728381A external-priority patent/JPS57122059A/ja
Priority claimed from JP1083281A external-priority patent/JPS57126463A/ja
Priority claimed from JP1083181A external-priority patent/JPS57126462A/ja
Application filed by 야마 구찌 아끼라, 닛뽕 케미파 가부시끼 가이샤 filed Critical 야마 구찌 아끼라
Publication of KR830009011A publication Critical patent/KR830009011A/ko
Application granted granted Critical
Publication of KR880001104B1 publication Critical patent/KR880001104B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR8200269A 1981-01-22 1982-01-22 구아니디노시클로헥산카복실산 유도체의 제조방법 Expired KR880001104B1 (ko)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP728481A JPS57122061A (en) 1981-01-22 1981-01-22 Novel cyclohexanecarboxylic acid derivative and its preparation
JP7283 1981-01-22
JP728681A JPS57122060A (en) 1981-01-22 1981-01-22 Carboxylic acid ester and its preparation
JP7284 1981-01-22
JP7286 1981-01-22
JP728381A JPS57122059A (en) 1981-01-22 1981-01-22 Novel cyclohexanecarboxylic acid derivative and its preparation
JP10831 1981-01-29
JP10832 1981-01-29
JP1083281A JPS57126463A (en) 1981-01-29 1981-01-29 Novel carboxylic ester and its preparation
JP1083181A JPS57126462A (en) 1981-01-29 1981-01-29 Novel carboxylic ester and its preparation

Publications (2)

Publication Number Publication Date
KR830009011A KR830009011A (ko) 1983-12-17
KR880001104B1 true KR880001104B1 (ko) 1988-06-29

Family

ID=27518804

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8200269A Expired KR880001104B1 (ko) 1981-01-22 1982-01-22 구아니디노시클로헥산카복실산 유도체의 제조방법

Country Status (11)

Country Link
US (1) US4465851A (en, 2012)
KR (1) KR880001104B1 (en, 2012)
BE (1) BE891790A (en, 2012)
BR (1) BR8200212A (en, 2012)
CA (1) CA1180716A (en, 2012)
CH (1) CH652119A5 (en, 2012)
DE (1) DE3201817A1 (en, 2012)
FR (1) FR2498183A1 (en, 2012)
IT (1) IT1191163B (en, 2012)
NL (1) NL8200110A (en, 2012)
SE (1) SE455789B (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0585130B1 (en) * 1992-08-27 1998-01-28 Shiseido Company Limited External preparation for skin containing a depigmentation agent
EP0989112B1 (en) * 1994-08-30 2004-04-14 Nagase ChemteX Corporation Intermediates for the preparation of guanidinomethyl cyclohexane carboxylic acid ester derivatives
AUPO227896A0 (en) * 1996-09-13 1996-10-03 Fujisawa Pharmaceutical Co., Ltd. Novel compounds and their preparation
AP1224A (en) 1998-03-19 2003-11-14 Bristol Myers Squibb Co Biphasic controlled release delivery system for high solubility pharmaceuticals and method.
GB9908410D0 (en) 1999-04-13 1999-06-09 Pfizer Ltd Pyridines
KR101942590B1 (ko) 2010-07-09 2019-01-25 비에이치브이 파르마, 인크. 레모글리플로진을 포함하는 짧은 반감기 약제용의 즉시/지연 조합 방출 전달 시스템

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA929942A (en) * 1968-10-14 1973-07-10 Okano Atsuji Esters and their production
JPS5339419B2 (en, 2012) * 1972-10-19 1978-10-21
JPS5140075A (en, 2012) * 1974-09-30 1976-04-03 Tokyo Shibaura Electric Co
SE460667B (sv) * 1979-09-20 1989-11-06 Nippon Chemiphar Co Cyklohexankarboxylsyraderivat, foerfarande foer framstaellning daerav samt naemnda derivat foer terapeutisk anvaendning
JPS5645454A (en) * 1979-09-20 1981-04-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid derivative and its preparation

Also Published As

Publication number Publication date
DE3201817A1 (de) 1982-08-19
IT8267060A0 (it) 1982-01-21
SE8200309L (sv) 1982-07-23
NL8200110A (nl) 1982-08-16
FR2498183B1 (en, 2012) 1985-05-10
KR830009011A (ko) 1983-12-17
BR8200212A (pt) 1982-11-09
BE891790A (fr) 1982-04-30
FR2498183A1 (fr) 1982-07-23
CH652119A5 (fr) 1985-10-31
IT1191163B (it) 1988-02-24
SE455789B (sv) 1988-08-08
DE3201817C2 (en, 2012) 1991-03-07
CA1180716A (en) 1985-01-08
US4465851A (en) 1984-08-14

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