KR880000974B1 - 6-(1-아실-1-하이드록시메틸)페니실란산 유도체및 이의 제조방법 - Google Patents

6-(1-아실-1-하이드록시메틸)페니실란산 유도체및 이의 제조방법 Download PDF

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Publication number
KR880000974B1
KR880000974B1 KR1019860002993A KR860002993A KR880000974B1 KR 880000974 B1 KR880000974 B1 KR 880000974B1 KR 1019860002993 A KR1019860002993 A KR 1019860002993A KR 860002993 A KR860002993 A KR 860002993A KR 880000974 B1 KR880000974 B1 KR 880000974B1
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KR
South Korea
Prior art keywords
title product
phenyl
ethyl acetate
nmr
hydroxy
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Expired
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KR1019860002993A
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English (en)
Korean (ko)
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KR860008187A (ko
Inventor
앤드류 리드3세 로렌스
Original Assignee
화이자 인코포레이티드
윌리엄 데이비스 헌
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Publication of KR860008187A publication Critical patent/KR860008187A/ko
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Publication of KR880000974B1 publication Critical patent/KR880000974B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019860002993A 1985-04-18 1986-04-17 6-(1-아실-1-하이드록시메틸)페니실란산 유도체및 이의 제조방법 Expired KR880000974B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72485785A 1985-04-18 1985-04-18
US24857 1985-04-18
US724.857 1985-04-18

Publications (2)

Publication Number Publication Date
KR860008187A KR860008187A (ko) 1986-11-12
KR880000974B1 true KR880000974B1 (ko) 1988-06-07

Family

ID=24912209

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860002993A Expired KR880000974B1 (ko) 1985-04-18 1986-04-17 6-(1-아실-1-하이드록시메틸)페니실란산 유도체및 이의 제조방법

Country Status (27)

Country Link
US (1) US4675186A (enExample)
EP (1) EP0201221B1 (enExample)
JP (1) JPS61243089A (enExample)
KR (1) KR880000974B1 (enExample)
CN (1) CN1003712B (enExample)
AT (1) ATE55133T1 (enExample)
AU (1) AU565926B2 (enExample)
CA (1) CA1270814A (enExample)
CS (1) CS255871B2 (enExample)
DD (1) DD258020A5 (enExample)
DE (1) DE3673057D1 (enExample)
DK (1) DK175186A (enExample)
EG (1) EG18288A (enExample)
ES (1) ES8800233A1 (enExample)
FI (1) FI85272C (enExample)
GR (1) GR860997B (enExample)
HU (1) HU196807B (enExample)
IE (1) IE58666B1 (enExample)
IL (1) IL78509A (enExample)
NO (2) NO861508L (enExample)
NZ (1) NZ215863A (enExample)
PH (2) PH22795A (enExample)
PL (1) PL147619B1 (enExample)
PT (1) PT82401B (enExample)
SU (1) SU1468425A3 (enExample)
YU (1) YU45013B (enExample)
ZA (1) ZA862876B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19540361A1 (de) * 1995-10-30 1997-05-07 Basf Ag Phenylessigsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung zur Bekämpfung von Schadpilzen und tierischen Schädlingen
FR2956400A1 (fr) * 2010-02-15 2011-08-19 Finorga Procede de preparation de composes adamantyles
CN109422765B (zh) * 2017-09-05 2020-08-28 香港理工大学深圳研究院 C类β-内酰胺酶抑制剂及其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1377661A (en) 1971-06-05 1974-12-18 Yamanouchi Pharma Co Ltd Oxofuryl ester derivatives of penicillin and cephalosporin
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
US4282149A (en) * 1977-03-21 1981-08-04 Massachusetts Institute Of Technology Carbon and oxygen analogs of penicillin
US4234579A (en) 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US4272439A (en) * 1978-06-02 1981-06-09 Schering Corporation 6-(Substituted-hydroxymethylene penams)
DE2927004A1 (de) * 1979-07-04 1981-05-27 Bayer Ag, 5090 Leverkusen Penicillansaeure-1,1-dioxide, ihre herstellung und ihre verwendung als arzneimittel als arzneimittel
US4287181A (en) * 1979-10-22 1981-09-01 Pfizer Inc. Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors
US4342768A (en) * 1979-10-22 1982-08-03 Pfizer Inc. Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics
JPS6019908B2 (ja) 1980-04-30 1985-05-18 カネボウ株式会社 １，３−ジオキソレン−２−オン誘導体
US4348264A (en) 1980-05-14 1982-09-07 Pfizer Inc. Photocatalyzed process for producing carbapenams and carbapen-2-ems
JPS5832882A (ja) 1981-07-18 1983-02-25 Kanebo Ltd ６−〔（ヘキサヒドロ−１ｈ−アゼピン−１−イル）メチレンアミノ〕ペニシラン酸の新規エステルおよびその製造法
US4457924A (en) 1981-12-22 1984-07-03 Pfizer, Inc. 1,1-Alkanediol dicarboxylate linked antibacterial agents
US4452796A (en) 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0083977A1 (en) 1982-01-11 1983-07-20 Pfizer Inc. 6-Alpha-hydroxymethylpenicillanic acid sulfone as a beta-lactamase inhibitor
US4503040A (en) 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4590073A (en) * 1984-10-22 1986-05-20 Pfizer Inc. 6-substituted penicillanic acid 1,1-dioxide compounds

Also Published As

Publication number Publication date
PL147619B1 (en) 1989-07-31
DD258020A5 (de) 1988-07-06
ATE55133T1 (de) 1990-08-15
AU565926B2 (en) 1987-10-01
CN86102736A (zh) 1986-10-15
AU5631886A (en) 1986-10-23
EP0201221B1 (en) 1990-08-01
CA1270814A (en) 1990-06-26
PT82401B (pt) 1988-08-17
JPS61243089A (ja) 1986-10-29
PH23560A (en) 1989-08-25
DK175186A (da) 1986-10-19
YU45013B (en) 1991-06-30
DK175186D0 (da) 1986-04-17
HU196807B (en) 1989-01-30
DE3673057D1 (de) 1990-09-06
US4675186A (en) 1987-06-23
EP0201221A1 (en) 1986-11-12
IE861014L (en) 1986-10-18
NO873599D0 (no) 1987-08-26
NZ215863A (en) 1988-07-28
JPH0534358B2 (enExample) 1993-05-21
NO873599L (no) 1986-10-20
PT82401A (en) 1986-05-01
EG18288A (en) 1992-10-30
YU62286A (en) 1988-02-29
IL78509A0 (en) 1986-08-31
NO861508L (no) 1986-10-20
HUT40669A (en) 1987-01-28
SU1468425A3 (ru) 1989-03-23
FI861630A0 (fi) 1986-04-17
CN1003712B (zh) 1989-03-29
PH22795A (en) 1988-12-12
ZA862876B (en) 1987-11-25
CS255871B2 (en) 1988-03-15
IL78509A (en) 1991-03-10
FI85272B (fi) 1991-12-13
GR860997B (en) 1986-08-12
FI85272C (fi) 1992-03-25
FI861630L (fi) 1986-10-19
IE58666B1 (en) 1993-11-03
ES554118A0 (es) 1987-10-16
CS275986A2 (en) 1987-07-16
KR860008187A (ko) 1986-11-12
ES8800233A1 (es) 1987-10-16

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