DK175186A - 6-(1-acyl-1-hydroxymethyl)-penicillansyre-derivater - Google Patents

6-(1-acyl-1-hydroxymethyl)-penicillansyre-derivater Download PDF

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Publication number
DK175186A
DK175186A DK175186A DK175186A DK175186A DK 175186 A DK175186 A DK 175186A DK 175186 A DK175186 A DK 175186A DK 175186 A DK175186 A DK 175186A DK 175186 A DK175186 A DK 175186A
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DK
Denmark
Prior art keywords
hydroxymethyl
acyl
acid derivatives
beta
alkyl
Prior art date
Application number
DK175186A
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English (en)
Other versions
DK175186D0 (da
Inventor
Iii Lawrence Andrew Reed
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK175186D0 publication Critical patent/DK175186D0/da
Publication of DK175186A publication Critical patent/DK175186A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

salte og alkylbromid, hvorpå den opnåede dibromforbin-delse viderebehandles under hensyntagen til opretholdelse af den ønskede stereokemi.
Forbindelsen er kraftigt virkende Ø-lactamase-inhibitorer og anvendes alene eller i kombination med andre antibiotics i lægemidler.
DK175186A 1985-04-18 1986-04-17 6-(1-acyl-1-hydroxymethyl)-penicillansyre-derivater DK175186A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72485785A 1985-04-18 1985-04-18
US72485785 1985-04-18

Publications (2)

Publication Number Publication Date
DK175186D0 DK175186D0 (da) 1986-04-17
DK175186A true DK175186A (da) 1986-10-19

Family

ID=24912209

Family Applications (1)

Application Number Title Priority Date Filing Date
DK175186A DK175186A (da) 1985-04-18 1986-04-17 6-(1-acyl-1-hydroxymethyl)-penicillansyre-derivater

Country Status (27)

Country Link
US (1) US4675186A (da)
EP (1) EP0201221B1 (da)
JP (1) JPS61243089A (da)
KR (1) KR880000974B1 (da)
CN (1) CN1003712B (da)
AT (1) ATE55133T1 (da)
AU (1) AU565926B2 (da)
CA (1) CA1270814A (da)
CS (1) CS255871B2 (da)
DD (1) DD258020A5 (da)
DE (1) DE3673057D1 (da)
DK (1) DK175186A (da)
EG (1) EG18288A (da)
ES (1) ES8800233A1 (da)
FI (1) FI85272C (da)
GR (1) GR860997B (da)
HU (1) HU196807B (da)
IE (1) IE58666B1 (da)
IL (1) IL78509A (da)
NO (2) NO861508L (da)
NZ (1) NZ215863A (da)
PH (2) PH22795A (da)
PL (1) PL147619B1 (da)
PT (1) PT82401B (da)
SU (1) SU1468425A3 (da)
YU (1) YU45013B (da)
ZA (1) ZA862876B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19540361A1 (de) * 1995-10-30 1997-05-07 Basf Ag Phenylessigsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung zur Bekämpfung von Schadpilzen und tierischen Schädlingen
FR2956400A1 (fr) * 2010-02-15 2011-08-19 Finorga Procede de preparation de composes adamantyles
CN109422765B (zh) * 2017-09-05 2020-08-28 香港理工大学深圳研究院 C类β-内酰胺酶抑制剂及其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1377661A (en) 1971-06-05 1974-12-18 Yamanouchi Pharma Co Ltd Oxofuryl ester derivatives of penicillin and cephalosporin
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
US4282149A (en) * 1977-03-21 1981-08-04 Massachusetts Institute Of Technology Carbon and oxygen analogs of penicillin
US4234579A (en) 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US4272439A (en) * 1978-06-02 1981-06-09 Schering Corporation 6-(Substituted-hydroxymethylene penams)
DE2927004A1 (de) * 1979-07-04 1981-05-27 Bayer Ag, 5090 Leverkusen Penicillansaeure-1,1-dioxide, ihre herstellung und ihre verwendung als arzneimittel als arzneimittel
US4342768A (en) * 1979-10-22 1982-08-03 Pfizer Inc. Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics
US4287181A (en) * 1979-10-22 1981-09-01 Pfizer Inc. Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors
JPS6019908B2 (ja) 1980-04-30 1985-05-18 カネボウ株式会社 １，３−ジオキソレン−２−オン誘導体
US4348264A (en) 1980-05-14 1982-09-07 Pfizer Inc. Photocatalyzed process for producing carbapenams and carbapen-2-ems
JPS5832882A (ja) 1981-07-18 1983-02-25 Kanebo Ltd ６−〔（ヘキサヒドロ−１ｈ−アゼピン−１−イル）メチレンアミノ〕ペニシラン酸の新規エステルおよびその製造法
US4457924A (en) 1981-12-22 1984-07-03 Pfizer, Inc. 1,1-Alkanediol dicarboxylate linked antibacterial agents
EP0083977A1 (en) 1982-01-11 1983-07-20 Pfizer Inc. 6-Alpha-hydroxymethylpenicillanic acid sulfone as a beta-lactamase inhibitor
US4452796A (en) 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4503040A (en) 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4590073A (en) * 1984-10-22 1986-05-20 Pfizer Inc. 6-substituted penicillanic acid 1,1-dioxide compounds

Also Published As

Publication number Publication date
IL78509A (en) 1991-03-10
HUT40669A (en) 1987-01-28
DK175186D0 (da) 1986-04-17
JPH0534358B2 (da) 1993-05-21
ES554118A0 (es) 1987-10-16
YU62286A (en) 1988-02-29
PH23560A (en) 1989-08-25
DD258020A5 (de) 1988-07-06
FI85272B (fi) 1991-12-13
FI861630A (fi) 1986-10-19
PT82401A (en) 1986-05-01
IE861014L (en) 1986-10-18
FI85272C (fi) 1992-03-25
CS275986A2 (en) 1987-07-16
IE58666B1 (en) 1993-11-03
SU1468425A3 (ru) 1989-03-23
NZ215863A (en) 1988-07-28
ATE55133T1 (de) 1990-08-15
ZA862876B (en) 1987-11-25
NO861508L (no) 1986-10-20
DE3673057D1 (de) 1990-09-06
NO873599D0 (no) 1987-08-26
IL78509A0 (en) 1986-08-31
CN1003712B (zh) 1989-03-29
FI861630A0 (fi) 1986-04-17
KR860008187A (ko) 1986-11-12
CA1270814A (en) 1990-06-26
EG18288A (en) 1992-10-30
EP0201221A1 (en) 1986-11-12
YU45013B (en) 1991-06-30
GR860997B (en) 1986-08-12
CN86102736A (zh) 1986-10-15
PT82401B (pt) 1988-08-17
JPS61243089A (ja) 1986-10-29
PL147619B1 (en) 1989-07-31
PH22795A (en) 1988-12-12
CS255871B2 (en) 1988-03-15
ES8800233A1 (es) 1987-10-16
US4675186A (en) 1987-06-23
HU196807B (en) 1989-01-30
AU5631886A (en) 1986-10-23
AU565926B2 (en) 1987-10-01
EP0201221B1 (en) 1990-08-01
KR880000974B1 (ko) 1988-06-07
NO873599L (no) 1986-10-20

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment