KR870007175A - 8α-아실아미노-에르고린 화합물의 제조방법 - Google Patents

8α-아실아미노-에르고린 화합물의 제조방법 Download PDF

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Publication number
KR870007175A
KR870007175A KR870000556A KR870000556A KR870007175A KR 870007175 A KR870007175 A KR 870007175A KR 870000556 A KR870000556 A KR 870000556A KR 870000556 A KR870000556 A KR 870000556A KR 870007175 A KR870007175 A KR 870007175A
Authority
KR
South Korea
Prior art keywords
compound
acid addition
addition salt
alkyl
methyl
Prior art date
Application number
KR870000556A
Other languages
English (en)
Korean (ko)
Inventor
레너 치글러 독토르
페터 노이만 독토르
발터 헤플리거 독토르
Original Assignee
예안 크라메르 · 한스 루돌프 하우스
산도즈 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 예안 크라메르 · 한스 루돌프 하우스, 산도즈 리미티드 filed Critical 예안 크라메르 · 한스 루돌프 하우스
Publication of KR870007175A publication Critical patent/KR870007175A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR870000556A 1986-01-24 1987-01-22 8α-아실아미노-에르고린 화합물의 제조방법 KR870007175A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3602058 1986-01-24
DEP3602058.3 1986-01-24

Publications (1)

Publication Number Publication Date
KR870007175A true KR870007175A (ko) 1987-08-17

Family

ID=6292510

Family Applications (1)

Application Number Title Priority Date Filing Date
KR870000556A KR870007175A (ko) 1986-01-24 1987-01-22 8α-아실아미노-에르고린 화합물의 제조방법

Country Status (18)

Country Link
JP (1) JPS62190184A (fr)
KR (1) KR870007175A (fr)
AU (1) AU6791487A (fr)
BE (1) BE1000039A4 (fr)
DK (1) DK35787A (fr)
ES (1) ES2003774A6 (fr)
FI (1) FI870293A (fr)
FR (1) FR2595699A1 (fr)
GB (1) GB2185743A (fr)
GR (1) GR870093B (fr)
HU (1) HUT45248A (fr)
IL (1) IL81355A0 (fr)
IT (1) IT1216783B (fr)
LU (1) LU86743A1 (fr)
NL (1) NL8700046A (fr)
PT (1) PT84184A (fr)
SE (1) SE8700250L (fr)
ZA (1) ZA87520B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
WO2012177962A1 (fr) * 2011-06-23 2012-12-27 Map Pharmaceuticals, Inc. Nouveaux analogues de fluoro-ergoline
WO2013095707A1 (fr) * 2011-12-19 2013-06-27 Map Pharmaceuticals, Inc. Nouveaux dérivés d'iso-ergoline
CA2974113A1 (fr) * 2015-01-20 2016-07-28 Xoc Pharmaceuticals, Inc. Composes d'isoergoline et leurs utilisations
CN107428745A (zh) 2015-01-20 2017-12-01 Xoc制药股份有限公司 麦角灵化合物及其用途
JP2020522504A (ja) 2017-06-01 2020-07-30 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ 多環式化合物およびそれらの用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
CH664568A5 (de) * 1984-01-12 1988-03-15 Sandoz Ag 8-alpha-acylaminoergoline.

Also Published As

Publication number Publication date
ZA87520B (en) 1988-09-28
FI870293A0 (fi) 1987-01-23
IT1216783B (it) 1990-03-14
FI870293A (fi) 1987-07-25
ES2003774A6 (es) 1988-11-16
GB8701274D0 (en) 1987-02-25
IT8747551A0 (it) 1987-01-22
DK35787A (da) 1987-07-25
NL8700046A (nl) 1987-08-17
LU86743A1 (fr) 1987-09-03
IL81355A0 (en) 1987-08-31
BE1000039A4 (fr) 1987-12-15
DK35787D0 (da) 1987-01-22
HUT45248A (en) 1988-06-28
FR2595699A1 (fr) 1987-09-18
SE8700250D0 (sv) 1987-01-22
PT84184A (pt) 1987-02-01
SE8700250L (sv) 1987-07-25
JPS62190184A (ja) 1987-08-20
GB2185743A (en) 1987-07-29
AU6791487A (en) 1987-07-30
GR870093B (en) 1987-05-25

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E902 Notification of reason for refusal
E601 Decision to refuse application