ATE18196T1 - 1,4-acyloxynaphthalenderivate, diese enthaltende kompositionen, verfahren fuer ihre herstellung und zwischenprodukte dafuer. - Google Patents
1,4-acyloxynaphthalenderivate, diese enthaltende kompositionen, verfahren fuer ihre herstellung und zwischenprodukte dafuer.Info
- Publication number
- ATE18196T1 ATE18196T1 AT83306509T AT83306509T ATE18196T1 AT E18196 T1 ATE18196 T1 AT E18196T1 AT 83306509 T AT83306509 T AT 83306509T AT 83306509 T AT83306509 T AT 83306509T AT E18196 T1 ATE18196 T1 AT E18196T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- substituted phenyl
- sup
- alkyl
- lower alkyl
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 150000002790 naphthalenes Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/12—Acetic acid esters
- C07C69/16—Acetic acid esters of dihydroxylic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
- C07C205/46—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group the carbon skeleton containing carbon atoms of quinone rings
- C07C205/47—Anthraquinones containing nitro groups
- C07C205/48—Anthraquinones containing nitro groups the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/24—Quinones containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/437,063 US4466981A (en) | 1982-10-27 | 1982-10-27 | Naphthalene anti-psoriatic agents |
| EP83306509A EP0107512B1 (de) | 1982-10-27 | 1983-10-26 | 1,4-Acyloxynaphthalenderivate, diese enthaltende Kompositionen, Verfahren für ihre Herstellung und Zwischenprodukte dafür |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE18196T1 true ATE18196T1 (de) | 1986-03-15 |
Family
ID=23734911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83306509T ATE18196T1 (de) | 1982-10-27 | 1983-10-26 | 1,4-acyloxynaphthalenderivate, diese enthaltende kompositionen, verfahren fuer ihre herstellung und zwischenprodukte dafuer. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4466981A (de) |
| EP (1) | EP0107512B1 (de) |
| JP (1) | JPS59104346A (de) |
| KR (1) | KR880002309B1 (de) |
| AT (1) | ATE18196T1 (de) |
| AU (1) | AU577772B2 (de) |
| CA (1) | CA1285575C (de) |
| DE (1) | DE3362342D1 (de) |
| DK (1) | DK164105C (de) |
| ES (1) | ES8504098A1 (de) |
| FI (1) | FI78901C (de) |
| HK (1) | HK3588A (de) |
| HU (1) | HU195470B (de) |
| IE (1) | IE56603B1 (de) |
| MX (1) | MX9203164A (de) |
| MY (1) | MY8700831A (de) |
| NO (1) | NO158216C (de) |
| NZ (1) | NZ206071A (de) |
| SG (1) | SG94687G (de) |
| ZA (1) | ZA837983B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4593120A (en) * | 1982-10-27 | 1986-06-03 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| DK35885A (da) * | 1984-01-27 | 1985-07-28 | Syntex Inc | Naphthalenderivater |
| US4833164A (en) * | 1985-05-08 | 1989-05-23 | E. I. Du Pont De Nemours And Company | 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors |
| ZA866823B (en) * | 1985-09-09 | 1988-04-27 | Syntex Inc | Naphthalene anti-psoritic agents |
| US4792556A (en) * | 1985-09-09 | 1988-12-20 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| US4933489A (en) * | 1985-10-24 | 1990-06-12 | Warner-Lambert Company | Process for the manufacture of 6-chloro-1,4-diacetoxy-2,3-dimethoxynaphthalene |
| DE3623360A1 (de) * | 1986-07-11 | 1988-01-14 | Cameron Iron Works Gmbh | Einrichtung mit einander benachbarten oberflaechen, zwischen denen hohe druecke und/oder hohe reibungsbeanspruchungen auftreten |
| AU626520B2 (en) * | 1987-03-09 | 1992-08-06 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| US5155132A (en) * | 1987-03-09 | 1992-10-13 | Syntex (U.S.A.) Inc. | Naphthalene lipoxygenase-inhibiting agents |
| US5134161A (en) * | 1987-03-09 | 1992-07-28 | Syntex (U.S.A.) Inc. | Method for treating disease states in mammals with naphthalene lipoxygenase-inhibiting agents |
| US4786652A (en) * | 1987-03-09 | 1988-11-22 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| US4758587A (en) * | 1987-03-09 | 1988-07-19 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| US5089657A (en) * | 1987-03-11 | 1992-02-18 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| US4925831A (en) * | 1987-06-11 | 1990-05-15 | Merck & Co., Inc. | Aminoalkyl naphthalenediols as host resistance enhancers against viral infection |
| US4840965A (en) * | 1987-07-07 | 1989-06-20 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
| US5242946A (en) * | 1988-10-27 | 1993-09-07 | Bio-Mega, Inc. | Treating herpes Viral infections |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3714206A (en) * | 1968-12-02 | 1973-01-30 | Gruenenthal Chemie | Benzo-2,3,1-diazaborines |
| CH575904A5 (de) * | 1972-02-16 | 1976-05-31 | Eisai Co Ltd | |
| US4115060A (en) * | 1977-10-03 | 1978-09-19 | Fmc Corporation | N-sulfonylimidazoles as peroxygen activators |
| US4255408A (en) * | 1977-11-11 | 1981-03-10 | Thermo-Mist Company | Process for removing sulfur and sulfur compounds from the effluent of industrial processes |
| US4181741A (en) * | 1977-11-18 | 1980-01-01 | E. I. Du Pont De Nemours And Company | Naphthalene miticides |
| US4321373A (en) * | 1978-03-18 | 1982-03-23 | Hoechst Aktiengesellschaft | 2-Hydroxy-3-naphthoic acid amides |
| US4229478A (en) * | 1978-06-05 | 1980-10-21 | Syntex (U.S.A.) Inc. | Naphthaquinone anti-psoriatic agents |
| US4255405A (en) * | 1978-06-05 | 1981-03-10 | Syntex (U.S.A.) Inc. | Naphthoquinone anti-psoriatic agents |
| US4374855A (en) * | 1981-04-03 | 1983-02-22 | Gaf Corporation | Fungicidal naphthylene diesters and mixtures thereof |
| US4593120A (en) * | 1982-10-27 | 1986-06-03 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
-
1982
- 1982-10-27 US US06/437,063 patent/US4466981A/en not_active Expired - Fee Related
-
1983
- 1983-10-26 FI FI833907A patent/FI78901C/fi not_active IP Right Cessation
- 1983-10-26 KR KR1019830005053A patent/KR880002309B1/ko not_active Expired
- 1983-10-26 HU HU833673A patent/HU195470B/hu not_active IP Right Cessation
- 1983-10-26 DK DK492283A patent/DK164105C/da not_active IP Right Cessation
- 1983-10-26 ES ES526785A patent/ES8504098A1/es not_active Expired
- 1983-10-26 AT AT83306509T patent/ATE18196T1/de active
- 1983-10-26 JP JP58199348A patent/JPS59104346A/ja active Granted
- 1983-10-26 NO NO833900A patent/NO158216C/no unknown
- 1983-10-26 ZA ZA837983A patent/ZA837983B/xx unknown
- 1983-10-26 AU AU20580/83A patent/AU577772B2/en not_active Ceased
- 1983-10-26 CA CA000439770A patent/CA1285575C/en not_active Expired - Lifetime
- 1983-10-26 DE DE8383306509T patent/DE3362342D1/de not_active Expired
- 1983-10-26 EP EP83306509A patent/EP0107512B1/de not_active Expired
- 1983-10-26 NZ NZ206071A patent/NZ206071A/en unknown
- 1983-10-26 IE IE2503/83A patent/IE56603B1/en not_active IP Right Cessation
-
1987
- 1987-10-29 SG SG946/87A patent/SG94687G/en unknown
- 1987-12-30 MY MY831/87A patent/MY8700831A/xx unknown
-
1988
- 1988-01-14 HK HK35/88A patent/HK3588A/xx unknown
-
1992
- 1992-06-23 MX MX9203164A patent/MX9203164A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT35238A (en) | 1985-06-28 |
| KR840006475A (ko) | 1984-11-30 |
| MY8700831A (en) | 1987-12-31 |
| JPH0520420B2 (de) | 1993-03-19 |
| FI833907A0 (fi) | 1983-10-26 |
| IE832503L (en) | 1984-04-27 |
| FI78901C (fi) | 1989-10-10 |
| EP0107512A1 (de) | 1984-05-02 |
| KR880002309B1 (ko) | 1988-10-22 |
| ES526785A0 (es) | 1985-04-16 |
| FI78901B (fi) | 1989-06-30 |
| ES8504098A1 (es) | 1985-04-16 |
| DK492283D0 (da) | 1983-10-26 |
| HK3588A (en) | 1988-01-22 |
| DE3362342D1 (en) | 1986-04-03 |
| DK164105C (da) | 1992-10-05 |
| NO158216B (no) | 1988-04-25 |
| NZ206071A (en) | 1986-09-10 |
| CA1285575C (en) | 1991-07-02 |
| AU2058083A (en) | 1984-05-03 |
| SG94687G (en) | 1988-05-06 |
| NO833900L (no) | 1984-04-30 |
| DK492283A (da) | 1984-04-28 |
| MX9203164A (es) | 1992-07-01 |
| FI833907L (fi) | 1984-04-28 |
| HU195470B (en) | 1988-05-30 |
| AU577772B2 (en) | 1988-10-06 |
| EP0107512B1 (de) | 1986-02-26 |
| NO158216C (no) | 1988-08-03 |
| DK164105B (da) | 1992-05-11 |
| US4466981A (en) | 1984-08-21 |
| JPS59104346A (ja) | 1984-06-16 |
| IE56603B1 (en) | 1991-10-09 |
| ZA837983B (en) | 1985-06-26 |
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| IL73878A0 (en) | Naphthalene derivatives,their preparation and pharmaceutical compositions containing them | |
| IL74162A0 (en) | Naphthalene derivatives,their preparation and pharmaceutical compositions containing them | |
| DK428686D0 (da) | Naphthalenderivater |