HUT45248A - Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds - Google Patents

Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds

Info

Publication number
HUT45248A
HUT45248A HU8792A HU9287A HUT45248A HU T45248 A HUT45248 A HU T45248A HU 8792 A HU8792 A HU 8792A HU 9287 A HU9287 A HU 9287A HU T45248 A HUT45248 A HU T45248A
Authority
HU
Hungary
Prior art keywords
8alpha
acylamino
pharmaceuticals
compounds
producing
Prior art date
Application number
HU8792A
Other languages
English (en)
Inventor
Rene Ziegler
Peter Neumann
Walter Haefliger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HUT45248A publication Critical patent/HUT45248A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU8792A 1986-01-24 1987-01-12 Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds HUT45248A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3602058 1986-01-24

Publications (1)

Publication Number Publication Date
HUT45248A true HUT45248A (en) 1988-06-28

Family

ID=6292510

Family Applications (1)

Application Number Title Priority Date Filing Date
HU8792A HUT45248A (en) 1986-01-24 1987-01-12 Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds

Country Status (18)

Country Link
JP (1) JPS62190184A (hu)
KR (1) KR870007175A (hu)
AU (1) AU6791487A (hu)
BE (1) BE1000039A4 (hu)
DK (1) DK35787A (hu)
ES (1) ES2003774A6 (hu)
FI (1) FI870293A (hu)
FR (1) FR2595699A1 (hu)
GB (1) GB2185743A (hu)
GR (1) GR870093B (hu)
HU (1) HUT45248A (hu)
IL (1) IL81355A0 (hu)
IT (1) IT1216783B (hu)
LU (1) LU86743A1 (hu)
NL (1) NL8700046A (hu)
PT (1) PT84184A (hu)
SE (1) SE8700250L (hu)
ZA (1) ZA87520B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
KR20140042868A (ko) * 2011-06-23 2014-04-07 맵 파마슈티컬스, 인코포레이티드 신규한 플루오로에르골린 유사체
EP2793580A4 (en) * 2011-12-19 2015-05-20 Map Pharmaceuticals Inc NEW DERIVATIVES OF ISO-ERGOLINE
US9657020B2 (en) 2015-01-20 2017-05-23 Xoc Pharmaceuticals, Inc. Ergoline compounds and uses thereof
BR112017015510A2 (pt) * 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo
CA3064274A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
CH664568A5 (de) * 1984-01-12 1988-03-15 Sandoz Ag 8-alpha-acylaminoergoline.

Also Published As

Publication number Publication date
KR870007175A (ko) 1987-08-17
FR2595699A1 (fr) 1987-09-18
IT8747551A0 (it) 1987-01-22
NL8700046A (nl) 1987-08-17
AU6791487A (en) 1987-07-30
DK35787A (da) 1987-07-25
GB8701274D0 (en) 1987-02-25
ES2003774A6 (es) 1988-11-16
DK35787D0 (da) 1987-01-22
LU86743A1 (fr) 1987-09-03
ZA87520B (en) 1988-09-28
IT1216783B (it) 1990-03-14
FI870293A (fi) 1987-07-25
SE8700250L (sv) 1987-07-25
GB2185743A (en) 1987-07-29
GR870093B (en) 1987-05-25
SE8700250D0 (sv) 1987-01-22
JPS62190184A (ja) 1987-08-20
FI870293A0 (fi) 1987-01-23
PT84184A (pt) 1987-02-01
IL81355A0 (en) 1987-08-31
BE1000039A4 (fr) 1987-12-15

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