KR870005991A - 아미드 유도체의 제조방법 - Google Patents
아미드 유도체의 제조방법 Download PDFInfo
- Publication number
- KR870005991A KR870005991A KR860010690A KR860010690A KR870005991A KR 870005991 A KR870005991 A KR 870005991A KR 860010690 A KR860010690 A KR 860010690A KR 860010690 A KR860010690 A KR 860010690A KR 870005991 A KR870005991 A KR 870005991A
- Authority
- KR
- South Korea
- Prior art keywords
- following formula
- group
- represented
- integer
- amide derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 하기식(IV)로 표시되는 카르복실산의 반응성 유도체를 하기식(V)로 표시되는 아민 유도체와 반응시켜 하기식(Ⅰ)로 표시되는 아미드 유도체의 제조방법.상기식에서, R1및 R2는 같거나 다를 수 있고 각각 저급알콕시기 또는 저급알콕시카르보닐기를 나타내고, R3는 수소원자 또는 저급알콕시기를 나타내고, m은 1 또는 2의 정수를 나타내고, Y는 하기식(II)로 표시되는 기이다.상기식에서 p는 2 내지 4의 정수 또는 하기식(III)으로 표시되는 기를 나타낸다.상기식에서, X는 수소원자, 할로겐원자 또는 메톡시기를 나타내고, q는 2 내지 4의 정수를 나타낸다.H-Y (V)상기식에서, R1, R2, R3, Y 및 m은 상기 정의와 같다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP280696/85 | 1985-12-13 | ||
JP28069685 | 1985-12-13 | ||
JP280696 | 1985-12-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR870005991A true KR870005991A (ko) | 1987-07-08 |
KR890003835B1 KR890003835B1 (ko) | 1989-10-05 |
Family
ID=17628670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019860010690A KR890003835B1 (ko) | 1985-12-13 | 1986-12-13 | 아미드 유도체의 제조방법 |
Country Status (6)
Country | Link |
---|---|
US (2) | US4795752A (ko) |
EP (1) | EP0226516B1 (ko) |
JP (1) | JPH0660160B2 (ko) |
KR (1) | KR890003835B1 (ko) |
DE (1) | DE3686245T2 (ko) |
HK (1) | HK143893A (ko) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0660160B2 (ja) * | 1985-12-13 | 1994-08-10 | テルモ株式会社 | アミド誘導体およびこれを含有する抗アレルギ−剤 |
US4859673A (en) * | 1986-04-28 | 1989-08-22 | Terumo Kabushiki Kaisha | Amide derivatives and antiallergic agents containing the same |
FR2635524B1 (fr) * | 1988-08-19 | 1992-04-24 | Adir | Nouveaux derives de benzopyrrolidinone, leur procede de preparation et les compositions pharmaceutiques les renfermant |
CA2015949A1 (en) * | 1989-05-22 | 1990-11-22 | Yasuo Ito | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same |
IE903957A1 (en) * | 1989-11-06 | 1991-05-08 | Sanofi Sa | Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present |
FR2663329B1 (fr) * | 1990-06-15 | 1992-10-16 | Sanofi Sa | Composes aromatiques amines, procede pour leur preparation et compositions pharmaceutiques les contenant. |
JP2671059B2 (ja) * | 1990-11-30 | 1997-10-29 | 富士レビオ株式会社 | ナフトエ酸誘導体 |
JPH0597672A (ja) * | 1991-10-08 | 1993-04-20 | Terumo Corp | アミド誘導体含有固形製剤およびその製造方法 |
EP0639376A1 (en) * | 1993-08-18 | 1995-02-22 | Terumo Kabushiki Kaisha | Liquid composition containing amide derivative |
WO1995019345A1 (fr) * | 1994-01-14 | 1995-07-20 | Nippon Shoji Kabushiki Kaisha | Derive du diazacycloalcanealkylsufonamide |
BR0114485A (pt) * | 2000-10-09 | 2003-11-18 | Novartis Ag | Amidas n-(4-ariloxipiperidin-1-ilalquil)cin micas como antagonistas de receptor de ccr33 |
WO2002030899A1 (en) * | 2000-10-09 | 2002-04-18 | Novartis Ag | N-(4-aryloxypiperidin-1-ylalkyl) cinnamic amides as ccr3 receptor antagonists |
GB0114699D0 (en) | 2001-06-15 | 2001-08-08 | Novartis Ag | Organic compounds |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1100104A (en) * | 1965-06-10 | 1968-01-24 | Mar Pha Soc D Etude Et D Expl | New esters of amino-alcohols and their acid addition salts |
US3700773A (en) * | 1969-06-25 | 1972-10-24 | Merck & Co Inc | Substituted phenylsulfamyl salicyclic acids and derivatives thereof in the treatment of inflammation |
US4250176A (en) * | 1976-12-21 | 1981-02-10 | Janssen Pharmaceutica N.V. | Piperazine derivatives |
AU532411B2 (en) * | 1979-03-01 | 1983-09-29 | Duphar International Research B.V. | Phenyl piperazine derivatives |
US4261990A (en) * | 1979-03-09 | 1981-04-14 | Ciba-Geigy Corporation | N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics |
JPS59118765A (ja) * | 1982-12-24 | 1984-07-09 | Fujisawa Pharmaceut Co Ltd | ピペラジン誘導体 |
US4673684A (en) * | 1984-04-04 | 1987-06-16 | Terumo Corporation | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient |
JPS60214766A (ja) * | 1984-04-04 | 1985-10-28 | Terumo Corp | アミド誘導体およびこれを有効成分として含有する5−リポキシゲナ−ゼ作用阻害剤 |
JPS61100566A (ja) * | 1984-10-22 | 1986-05-19 | Dainippon Pharmaceut Co Ltd | 桂皮酸アミド誘導体およびその塩 |
IT1190375B (it) * | 1985-06-20 | 1988-02-16 | Recordati Chem Pharm | N-benzidrildiazacicloalchil-alcanilidi ad attivita' antianafilattica ed antibroncospastica |
JPH0660160B2 (ja) * | 1985-12-13 | 1994-08-10 | テルモ株式会社 | アミド誘導体およびこれを含有する抗アレルギ−剤 |
US4792553A (en) * | 1986-02-04 | 1988-12-20 | Terumo Kabushiki Kaisha | Diene derivatives and vasodilators containing the same |
JPS6355510A (ja) * | 1986-05-10 | 1988-03-10 | Canon Inc | ズ−ムレンズ |
JPH0672630B2 (ja) * | 1990-07-12 | 1994-09-14 | 株式会社富士鉄工所 | 油圧式動力伝達継手 |
JP2572876B2 (ja) * | 1990-07-12 | 1997-01-16 | 株式会社富士鉄工所 | 油圧式動力伝達継手 |
-
1986
- 1986-04-28 JP JP61096638A patent/JPH0660160B2/ja not_active Expired - Lifetime
- 1986-12-08 US US06/939,135 patent/US4795752A/en not_active Expired - Lifetime
- 1986-12-12 DE DE8686402795T patent/DE3686245T2/de not_active Expired - Fee Related
- 1986-12-12 EP EP86402795A patent/EP0226516B1/en not_active Expired - Lifetime
- 1986-12-13 KR KR1019860010690A patent/KR890003835B1/ko not_active IP Right Cessation
-
1988
- 1988-08-31 US US07/238,604 patent/US4906631A/en not_active Expired - Lifetime
-
1993
- 1993-12-30 HK HK1438/93A patent/HK143893A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3686245T2 (de) | 1993-02-18 |
EP0226516A2 (en) | 1987-06-24 |
DE3686245D1 (de) | 1992-09-03 |
JPS62228059A (ja) | 1987-10-06 |
HK143893A (en) | 1994-01-07 |
EP0226516B1 (en) | 1992-07-29 |
KR890003835B1 (ko) | 1989-10-05 |
JPH0660160B2 (ja) | 1994-08-10 |
US4906631A (en) | 1990-03-06 |
EP0226516A3 (en) | 1988-09-07 |
US4795752A (en) | 1989-01-03 |
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G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20020918 Year of fee payment: 14 |
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LAPS | Lapse due to unpaid annual fee |