KR860001045A - 메발로노락톤의 나프틸 동족체의 제조방법 - Google Patents
메발로노락톤의 나프틸 동족체의 제조방법 Download PDFInfo
- Publication number
- KR860001045A KR860001045A KR1019850005206A KR850005206A KR860001045A KR 860001045 A KR860001045 A KR 860001045A KR 1019850005206 A KR1019850005206 A KR 1019850005206A KR 850005206 A KR850005206 A KR 850005206A KR 860001045 A KR860001045 A KR 860001045A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- formula
- ester
- producing
- free acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
- C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63380984A | 1984-07-24 | 1984-07-24 | |
| US633809 | 1984-07-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR860001045A true KR860001045A (ko) | 1986-02-22 |
Family
ID=24541204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019850005206A KR860001045A (ko) | 1984-07-24 | 1985-07-22 | 메발로노락톤의 나프틸 동족체의 제조방법 |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS6137754A (de) |
| KR (1) | KR860001045A (de) |
| AU (1) | AU4522685A (de) |
| BE (1) | BE902914A (de) |
| DE (1) | DE3525256A1 (de) |
| DK (1) | DK333785A (de) |
| ES (1) | ES8705356A1 (de) |
| FI (1) | FI852851L (de) |
| FR (1) | FR2568248A1 (de) |
| GB (1) | GB2162179A (de) |
| GR (1) | GR851805B (de) |
| HU (1) | HUT39142A (de) |
| IL (1) | IL75874A0 (de) |
| IT (1) | IT1200095B (de) |
| LU (1) | LU86012A1 (de) |
| NL (1) | NL8502010A (de) |
| PH (1) | PH21444A (de) |
| PL (1) | PL254654A1 (de) |
| PT (1) | PT80845B (de) |
| SE (1) | SE8503556L (de) |
| ZA (1) | ZA855594B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5091378A (en) * | 1987-05-22 | 1992-02-25 | E. R. Squibb & Sons, Inc. | Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method |
| US4904646A (en) * | 1987-05-22 | 1990-02-27 | E. R. Squibb & Sons, Inc. | Phosphorus-containing HMG-COA reductase inhibitors |
| DE3722807A1 (de) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
| US4792614A (en) * | 1987-08-05 | 1988-12-20 | American Home Products Corporation | Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase |
| US4812583A (en) * | 1987-09-11 | 1989-03-14 | American Home Products Corporation | Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase |
| DE3818570A1 (de) * | 1988-06-01 | 1989-12-21 | Boehringer Mannheim Gmbh | Neue 6-substituierte-4-hydroxy-tetrahydro-pyran -2-on-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen |
| US5506219A (en) * | 1988-08-29 | 1996-04-09 | E. R. Squibb & Sons, Inc. | Pyridine anchors for HMG-CoA reductase inhibitors |
| CA2185961A1 (en) * | 1996-09-19 | 1998-03-20 | K.S. Keshava Murthy | Process for producing simvastatin |
| US20010006644A1 (en) | 1997-07-31 | 2001-07-05 | David J. Bova | Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night |
| KR100836960B1 (ko) | 2007-09-07 | 2008-06-10 | 주식회사 서울제약 | 새로운 나이아신 제어방출형 제제 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55132595A (en) * | 1979-04-04 | 1980-10-15 | Nec Corp | Semiconductor circuit |
-
1985
- 1985-07-12 HU HU852696A patent/HUT39142A/hu unknown
- 1985-07-12 NL NL8502010A patent/NL8502010A/nl not_active Application Discontinuation
- 1985-07-15 DE DE19853525256 patent/DE3525256A1/de not_active Withdrawn
- 1985-07-16 FR FR8510988A patent/FR2568248A1/fr active Pending
- 1985-07-17 BE BE1/011302A patent/BE902914A/fr not_active IP Right Cessation
- 1985-07-22 KR KR1019850005206A patent/KR860001045A/ko not_active Application Discontinuation
- 1985-07-22 SE SE8503556A patent/SE8503556L/xx not_active Application Discontinuation
- 1985-07-22 PT PT80845A patent/PT80845B/pt unknown
- 1985-07-22 GB GB08518490A patent/GB2162179A/en not_active Withdrawn
- 1985-07-22 FI FI852851A patent/FI852851L/fi not_active Application Discontinuation
- 1985-07-22 ES ES545454A patent/ES8705356A1/es not_active Expired
- 1985-07-22 AU AU45226/85A patent/AU4522685A/en not_active Abandoned
- 1985-07-22 PH PH32550A patent/PH21444A/en unknown
- 1985-07-22 DK DK333785A patent/DK333785A/da not_active Application Discontinuation
- 1985-07-22 IL IL75874A patent/IL75874A0/xx unknown
- 1985-07-22 LU LU86012A patent/LU86012A1/fr unknown
- 1985-07-22 GR GR851805A patent/GR851805B/el unknown
- 1985-07-23 IT IT8548385A patent/IT1200095B/it active
- 1985-07-23 JP JP16278685A patent/JPS6137754A/ja active Pending
- 1985-07-23 PL PL25465485A patent/PL254654A1/xx unknown
- 1985-07-24 ZA ZA855594A patent/ZA855594B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT80845A (en) | 1985-08-01 |
| JPS6137754A (ja) | 1986-02-22 |
| IT1200095B (it) | 1989-01-05 |
| AU4522685A (en) | 1986-01-30 |
| BE902914A (fr) | 1986-01-17 |
| SE8503556L (sv) | 1986-01-25 |
| ES545454A0 (es) | 1987-05-01 |
| DE3525256A1 (de) | 1986-01-30 |
| SE8503556D0 (sv) | 1985-07-22 |
| FI852851L (fi) | 1986-01-25 |
| ES8705356A1 (es) | 1987-05-01 |
| IL75874A0 (en) | 1985-11-29 |
| GB2162179A (en) | 1986-01-29 |
| GR851805B (de) | 1985-11-26 |
| FI852851A0 (fi) | 1985-07-22 |
| FR2568248A1 (fr) | 1986-01-31 |
| PT80845B (en) | 1987-03-24 |
| PL254654A1 (en) | 1986-08-26 |
| PH21444A (en) | 1987-10-20 |
| LU86012A1 (fr) | 1986-02-12 |
| GB8518490D0 (en) | 1985-08-29 |
| NL8502010A (nl) | 1986-02-17 |
| IT8548385A0 (it) | 1985-07-23 |
| ZA855594B (en) | 1987-02-25 |
| DK333785D0 (da) | 1985-07-22 |
| HUT39142A (en) | 1986-08-28 |
| DK333785A (da) | 1986-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application |