HUT39142A - Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them

Info

Publication number
HUT39142A
HUT39142A HU852696A HU269685A HUT39142A HU T39142 A HUT39142 A HU T39142A HU 852696 A HU852696 A HU 852696A HU 269685 A HU269685 A HU 269685A HU T39142 A HUT39142 A HU T39142A
Authority
HU
Hungary
Prior art keywords
mevalolactone
naphtyl
analogues
derivatives
producing
Prior art date
Application number
HU852696A
Other languages
English (en)
Hungarian (hu)
Inventor
Paul L Anderson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HUT39142A publication Critical patent/HUT39142A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
HU852696A 1984-07-24 1985-07-12 Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them HUT39142A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63380984A 1984-07-24 1984-07-24

Publications (1)

Publication Number Publication Date
HUT39142A true HUT39142A (en) 1986-08-28

Family

ID=24541204

Family Applications (1)

Application Number Title Priority Date Filing Date
HU852696A HUT39142A (en) 1984-07-24 1985-07-12 Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them

Country Status (21)

Country Link
JP (1) JPS6137754A (de)
KR (1) KR860001045A (de)
AU (1) AU4522685A (de)
BE (1) BE902914A (de)
DE (1) DE3525256A1 (de)
DK (1) DK333785A (de)
ES (1) ES8705356A1 (de)
FI (1) FI852851L (de)
FR (1) FR2568248A1 (de)
GB (1) GB2162179A (de)
GR (1) GR851805B (de)
HU (1) HUT39142A (de)
IL (1) IL75874A0 (de)
IT (1) IT1200095B (de)
LU (1) LU86012A1 (de)
NL (1) NL8502010A (de)
PH (1) PH21444A (de)
PL (1) PL254654A1 (de)
PT (1) PT80845B (de)
SE (1) SE8503556L (de)
ZA (1) ZA855594B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091378A (en) * 1987-05-22 1992-02-25 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
US4904646A (en) * 1987-05-22 1990-02-27 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-COA reductase inhibitors
DE3722807A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US4792614A (en) * 1987-08-05 1988-12-20 American Home Products Corporation Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
US4812583A (en) * 1987-09-11 1989-03-14 American Home Products Corporation Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
DE3818570A1 (de) * 1988-06-01 1989-12-21 Boehringer Mannheim Gmbh Neue 6-substituierte-4-hydroxy-tetrahydro-pyran -2-on-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
CA2185961A1 (en) * 1996-09-19 1998-03-20 K.S. Keshava Murthy Process for producing simvastatin
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
KR100836960B1 (ko) 2007-09-07 2008-06-10 주식회사 서울제약 새로운 나이아신 제어방출형 제제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55132595A (en) * 1979-04-04 1980-10-15 Nec Corp Semiconductor circuit

Also Published As

Publication number Publication date
ES8705356A1 (es) 1987-05-01
ES545454A0 (es) 1987-05-01
FI852851A0 (fi) 1985-07-22
GR851805B (de) 1985-11-26
FI852851L (fi) 1986-01-25
PL254654A1 (en) 1986-08-26
IT1200095B (it) 1989-01-05
KR860001045A (ko) 1986-02-22
GB2162179A (en) 1986-01-29
JPS6137754A (ja) 1986-02-22
DE3525256A1 (de) 1986-01-30
SE8503556D0 (sv) 1985-07-22
PT80845A (en) 1985-08-01
ZA855594B (en) 1987-02-25
GB8518490D0 (en) 1985-08-29
DK333785D0 (da) 1985-07-22
SE8503556L (sv) 1986-01-25
IL75874A0 (en) 1985-11-29
AU4522685A (en) 1986-01-30
DK333785A (da) 1986-01-25
LU86012A1 (fr) 1986-02-12
PT80845B (en) 1987-03-24
PH21444A (en) 1987-10-20
BE902914A (fr) 1986-01-17
NL8502010A (nl) 1986-02-17
FR2568248A1 (fr) 1986-01-31
IT8548385A0 (it) 1985-07-23

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HUT39142A (en) Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them