PL254654A1 - Method of obtaining naphtyl analogues of mevalonolaktone and their derivatives - Google Patents

Method of obtaining naphtyl analogues of mevalonolaktone and their derivatives

Info

Publication number
PL254654A1
PL254654A1 PL25465485A PL25465485A PL254654A1 PL 254654 A1 PL254654 A1 PL 254654A1 PL 25465485 A PL25465485 A PL 25465485A PL 25465485 A PL25465485 A PL 25465485A PL 254654 A1 PL254654 A1 PL 254654A1
Authority
PL
Poland
Prior art keywords
mevalonolaktone
naphtyl
analogues
derivatives
obtaining
Prior art date
Application number
PL25465485A
Other languages
English (en)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of PL254654A1 publication Critical patent/PL254654A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
PL25465485A 1984-07-24 1985-07-23 Method of obtaining naphtyl analogues of mevalonolaktone and their derivatives PL254654A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63380984A 1984-07-24 1984-07-24

Publications (1)

Publication Number Publication Date
PL254654A1 true PL254654A1 (en) 1986-08-26

Family

ID=24541204

Family Applications (1)

Application Number Title Priority Date Filing Date
PL25465485A PL254654A1 (en) 1984-07-24 1985-07-23 Method of obtaining naphtyl analogues of mevalonolaktone and their derivatives

Country Status (21)

Country Link
JP (1) JPS6137754A (de)
KR (1) KR860001045A (de)
AU (1) AU4522685A (de)
BE (1) BE902914A (de)
DE (1) DE3525256A1 (de)
DK (1) DK333785A (de)
ES (1) ES8705356A1 (de)
FI (1) FI852851L (de)
FR (1) FR2568248A1 (de)
GB (1) GB2162179A (de)
GR (1) GR851805B (de)
HU (1) HUT39142A (de)
IL (1) IL75874A0 (de)
IT (1) IT1200095B (de)
LU (1) LU86012A1 (de)
NL (1) NL8502010A (de)
PH (1) PH21444A (de)
PL (1) PL254654A1 (de)
PT (1) PT80845B (de)
SE (1) SE8503556L (de)
ZA (1) ZA855594B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091378A (en) * 1987-05-22 1992-02-25 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
US4904646A (en) * 1987-05-22 1990-02-27 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-COA reductase inhibitors
DE3722807A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US4792614A (en) * 1987-08-05 1988-12-20 American Home Products Corporation Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
US4812583A (en) * 1987-09-11 1989-03-14 American Home Products Corporation Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
DE3818570A1 (de) * 1988-06-01 1989-12-21 Boehringer Mannheim Gmbh Neue 6-substituierte-4-hydroxy-tetrahydro-pyran -2-on-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
CA2185961A1 (en) * 1996-09-19 1998-03-20 K.S. Keshava Murthy Process for producing simvastatin
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
KR100836960B1 (ko) 2007-09-07 2008-06-10 주식회사 서울제약 새로운 나이아신 제어방출형 제제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55132595A (en) * 1979-04-04 1980-10-15 Nec Corp Semiconductor circuit

Also Published As

Publication number Publication date
PT80845A (en) 1985-08-01
JPS6137754A (ja) 1986-02-22
IT1200095B (it) 1989-01-05
AU4522685A (en) 1986-01-30
BE902914A (fr) 1986-01-17
SE8503556L (sv) 1986-01-25
ES545454A0 (es) 1987-05-01
DE3525256A1 (de) 1986-01-30
SE8503556D0 (sv) 1985-07-22
FI852851L (fi) 1986-01-25
ES8705356A1 (es) 1987-05-01
IL75874A0 (en) 1985-11-29
GB2162179A (en) 1986-01-29
GR851805B (de) 1985-11-26
FI852851A0 (fi) 1985-07-22
FR2568248A1 (fr) 1986-01-31
PT80845B (en) 1987-03-24
PH21444A (en) 1987-10-20
LU86012A1 (fr) 1986-02-12
GB8518490D0 (en) 1985-08-29
NL8502010A (nl) 1986-02-17
IT8548385A0 (it) 1985-07-23
ZA855594B (en) 1987-02-25
DK333785D0 (da) 1985-07-22
HUT39142A (en) 1986-08-28
KR860001045A (ko) 1986-02-22
DK333785A (da) 1986-01-25

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