KR910009636A - 오메가-아미노-알파-히드록시 카르복실산의 제조방법 - Google Patents

오메가-아미노-알파-히드록시 카르복실산의 제조방법 Download PDF

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Publication number
KR910009636A
KR910009636A KR1019900019479A KR900019479A KR910009636A KR 910009636 A KR910009636 A KR 910009636A KR 1019900019479 A KR1019900019479 A KR 1019900019479A KR 900019479 A KR900019479 A KR 900019479A KR 910009636 A KR910009636 A KR 910009636A
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South Korea
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group
carboxylic acid
hydroxy carboxylic
amino
ester
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KR1019900019479A
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English (en)
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KR0159101B1 (ko
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사또미 다까하시
요시후미 야나기다
Original Assignee
다찌 다다스
가네가후찌가가꾸고오교 가부시끼가이샤
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Publication of KR910009636A publication Critical patent/KR910009636A/ko
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Publication of KR0159101B1 publication Critical patent/KR0159101B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

오메가-아미노-아파-히드록시 카르복실산의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. (1)하기식(I)의-아미노산의-에스테르를 산성조건하에 아질산과 반응시켜 아미노기를 히드록시기로 전환시켜 하기식(Ⅱ)의-알콕시카르보닐--히드록시카르복실산을 수득하고, (2)-알콕시카르보닐--히드록시 카르복실산(Ⅱ)을 암모니아와 반응시켜 알콕시 카르보닐기를 아미드기로 전환시켜 하기식(Ⅲ)의-아미모카르보닐--히드록시 카르복실산을 수득하고, (3)-아미노카르보닐--히드록시 카르복실산 (Ⅲ)을 활성 할로겐과 반응시켜 아미도기를 아미노기로 전환시켜-아니모--히드록시 카르복실산(Ⅳ)을 수득하는 : 단계들로 이루어지는, 하기식(Ⅳ)의 광학적 활성-아미노--히드록시 카르복실산의 제조방법.
    (상기식에서 n은 1 또는 2 이고 R은 C1C7알킬기 또는 아랄킬기이다.)
  2. 제1항에 있어서, (1)단계에서 아세트산으로 산성화된 수성 매체내에서 아질산의 알킬기 금속염 및 알칼리 토금속염으로 이루어지는 군에서 선택되는 적어도 하나의 아릴산염으로써 아미노기를 히드록시기로 전환시키는 방법.
  3. 제1항에 있어서, 차아염소산나트륨을 사용하여 할로겐을 생성시키는 방법.
  4. 제1항에 있어서, 화합물(I)이 L--아미노산의-에스테르인 방법.
  5. 제4항에 있어서,-에스테르가 메틸에스테르인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900019479A 1989-11-29 1990-11-29 오메가-아미노-알파-히드록시 카르복실산의 제조방법 KR0159101B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP311519/89 1989-11-29
JP1311519A JPH03170453A (ja) 1989-11-29 1989-11-29 ω―アミノ―α―ヒドロキシカルボン酸の製造法

Publications (2)

Publication Number Publication Date
KR910009636A true KR910009636A (ko) 1991-06-28
KR0159101B1 KR0159101B1 (ko) 1999-01-15

Family

ID=18018217

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900019479A KR0159101B1 (ko) 1989-11-29 1990-11-29 오메가-아미노-알파-히드록시 카르복실산의 제조방법

Country Status (3)

Country Link
EP (1) EP0430234A3 (ko)
JP (1) JPH03170453A (ko)
KR (1) KR0159101B1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1036340C (zh) * 1992-06-17 1997-11-05 成都制药四厂 L－(－)－α－羟基－γ－氨基丁酸合成方法
EP4382529A1 (en) 2022-12-07 2024-06-12 Bayer Consumer Care AG A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3823187A (en) * 1972-06-19 1974-07-09 Bristol Myers Co Production of l(-)-gamma-amino-alpha-hydroxybutyric acid
JPS62190093A (ja) * 1986-02-17 1987-08-20 Toyo Jozo Co Ltd リンゴ酸β−モノアルキルエステルまたはイソセリンの製造法

Also Published As

Publication number Publication date
EP0430234A3 (en) 1991-10-23
JPH03170453A (ja) 1991-07-24
KR0159101B1 (ko) 1999-01-15
EP0430234A2 (en) 1991-06-05

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