KR860000103B1 - 3'-치환-5'-(2-아미노-4-피리딜)-1', 2', 4'-트리아졸류의 제조 방법 - Google Patents

3'-치환-5'-(2-아미노-4-피리딜)-1', 2', 4'-트리아졸류의 제조 방법 Download PDF

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Publication number
KR860000103B1
KR860000103B1 KR8203906A KR820003906A KR860000103B1 KR 860000103 B1 KR860000103 B1 KR 860000103B1 KR 8203906 A KR8203906 A KR 8203906A KR 820003906 A KR820003906 A KR 820003906A KR 860000103 B1 KR860000103 B1 KR 860000103B1
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South Korea
Prior art keywords
pyridyl
formula
triazole
compounds
histamine
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KR8203906A
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Korean (ko)
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KR840001155A (ko
Inventor
앤드류 리핀스키 크리스토퍼
로렌스 라마티나 죤
Original Assignee
윌리암 지이. 멕크리이리
화이자 인코포레이티드
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Publication of KR840001155A publication Critical patent/KR840001155A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR8203906A 1981-08-31 1982-08-30 3'-치환-5'-(2-아미노-4-피리딜)-1', 2', 4'-트리아졸류의 제조 방법 Expired KR860000103B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29822481A 1981-08-31 1981-08-31
US298224 1981-08-31

Publications (2)

Publication Number Publication Date
KR840001155A KR840001155A (ko) 1984-03-28
KR860000103B1 true KR860000103B1 (ko) 1986-02-19

Family

ID=23149579

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KR8203906A Expired KR860000103B1 (ko) 1981-08-31 1982-08-30 3'-치환-5'-(2-아미노-4-피리딜)-1', 2', 4'-트리아졸류의 제조 방법

Country Status (19)

Country Link
EP (1) EP0074229B1 (enExample)
JP (1) JPS5846083A (enExample)
KR (1) KR860000103B1 (enExample)
AR (1) AR230994A1 (enExample)
AT (1) ATE19078T1 (enExample)
AU (1) AU534063B2 (enExample)
CA (1) CA1177485A (enExample)
DE (1) DE3270423D1 (enExample)
DK (1) DK160303C (enExample)
ES (1) ES8308324A1 (enExample)
FI (1) FI78085C (enExample)
GR (1) GR77241B (enExample)
HU (1) HU188328B (enExample)
IE (1) IE53586B1 (enExample)
IL (1) IL66673A (enExample)
PH (1) PH17423A (enExample)
PL (1) PL134315B1 (enExample)
PT (1) PT75481A (enExample)
YU (1) YU42795B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004229392A1 (en) * 2003-04-09 2004-10-28 Exelixis, Inc. Tie-2 modulators and methods of use
AR076753A1 (es) 2009-05-07 2011-07-06 Gruenenthal Chemie Derivados de carboxamida y urea aromaticas sustituidas como ligandos del receptor de vanilloides.
EP2431035A1 (en) * 2010-09-16 2012-03-21 Æterna Zentaris GmbH Novel Triazole Derivatives with Improved Receptor Activity and Bioavailability Properties as Ghrelin Antagonists of Growth Hormone Secretagogue Receptors
AU2020417293A1 (en) 2020-01-03 2022-09-01 Berg Llc Polycyclic amides as UBE2K modulators for treating cancer
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276297A (en) * 1979-06-18 1981-06-30 Pfizer Inc. Pyridylaminotriazole therapeutic agents

Also Published As

Publication number Publication date
DE3270423D1 (en) 1986-05-15
CA1177485A (en) 1984-11-06
AU8784182A (en) 1983-03-31
PL238095A1 (en) 1984-03-26
JPS5846083A (ja) 1983-03-17
ATE19078T1 (de) 1986-04-15
ES515366A0 (es) 1983-08-16
FI822999A0 (fi) 1982-08-30
EP0074229A1 (en) 1983-03-16
DK386882A (da) 1983-04-07
DK160303B (da) 1991-02-25
FI78085B (fi) 1989-02-28
AR230994A1 (es) 1984-08-31
FI78085C (fi) 1989-06-12
EP0074229B1 (en) 1986-04-09
AU534063B2 (en) 1984-01-05
IL66673A (en) 1986-04-29
PH17423A (en) 1984-08-08
YU196382A (en) 1985-03-20
YU42795B (en) 1988-12-31
GR77241B (enExample) 1984-09-11
DK160303C (da) 1991-08-05
HU188328B (en) 1986-04-28
KR840001155A (ko) 1984-03-28
PT75481A (en) 1982-09-01
IE822087L (en) 1983-02-28
PL134315B1 (en) 1985-08-31
IE53586B1 (en) 1988-12-21
IL66673A0 (en) 1982-12-31
ES8308324A1 (es) 1983-08-16
FI822999L (fi) 1983-03-01

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