PT75481A - Process for preparing 3'-substituted-5'-(2-amino-4-pyridil)-1',2',4',-triazoles - Google Patents

Process for preparing 3'-substituted-5'-(2-amino-4-pyridil)-1',2',4',-triazoles

Info

Publication number
PT75481A
PT75481A PT75481A PT7548182A PT75481A PT 75481 A PT75481 A PT 75481A PT 75481 A PT75481 A PT 75481A PT 7548182 A PT7548182 A PT 7548182A PT 75481 A PT75481 A PT 75481A
Authority
PT
Portugal
Prior art keywords
pyridil
triazoles
amino
substituted
preparing
Prior art date
Application number
PT75481A
Other languages
English (en)
Inventor
Christopher Andrew Lipinski
John Lawrence Lamattina
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT75481A publication Critical patent/PT75481A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT75481A 1981-08-31 1982-08-30 Process for preparing 3'-substituted-5'-(2-amino-4-pyridil)-1',2',4',-triazoles PT75481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29822481A 1981-08-31 1981-08-31

Publications (1)

Publication Number Publication Date
PT75481A true PT75481A (en) 1982-09-01

Family

ID=23149579

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75481A PT75481A (en) 1981-08-31 1982-08-30 Process for preparing 3'-substituted-5'-(2-amino-4-pyridil)-1',2',4',-triazoles

Country Status (19)

Country Link
EP (1) EP0074229B1 (pt)
JP (1) JPS5846083A (pt)
KR (1) KR860000103B1 (pt)
AR (1) AR230994A1 (pt)
AT (1) ATE19078T1 (pt)
AU (1) AU534063B2 (pt)
CA (1) CA1177485A (pt)
DE (1) DE3270423D1 (pt)
DK (1) DK160303C (pt)
ES (1) ES8308324A1 (pt)
FI (1) FI78085C (pt)
GR (1) GR77241B (pt)
HU (1) HU188328B (pt)
IE (1) IE53586B1 (pt)
IL (1) IL66673A (pt)
PH (1) PH17423A (pt)
PL (1) PL134315B1 (pt)
PT (1) PT75481A (pt)
YU (1) YU42795B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8178570B2 (en) 2003-04-09 2012-05-15 Exelixis, Inc. Tie-2 modulators and methods of use
BRPI1011192A2 (pt) * 2009-05-07 2016-03-15 Gruenenthal Gmbh derivados de carboxamida e ureia aromáticas substituídas como ligantes de receptor de vaniloide, composição farmacêutica, uso e processo para preparação dos referidos derivados
EP2431035A1 (en) * 2010-09-16 2012-03-21 Æterna Zentaris GmbH Novel Triazole Derivatives with Improved Receptor Activity and Bioavailability Properties as Ghrelin Antagonists of Growth Hormone Secretagogue Receptors
JP2023509452A (ja) 2020-01-03 2023-03-08 バーグ エルエルシー がんを処置するためのｕｂｅ２ｋモジュレータとしての多環式アミド
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276297A (en) * 1979-06-18 1981-06-30 Pfizer Inc. Pyridylaminotriazole therapeutic agents

Also Published As

Publication number Publication date
IL66673A0 (en) 1982-12-31
DK160303C (da) 1991-08-05
KR860000103B1 (ko) 1986-02-19
CA1177485A (en) 1984-11-06
IL66673A (en) 1986-04-29
FI822999A0 (fi) 1982-08-30
ES515366A0 (es) 1983-08-16
AU8784182A (en) 1983-03-31
IE822087L (en) 1983-02-28
JPS5846083A (ja) 1983-03-17
FI78085C (fi) 1989-06-12
ES8308324A1 (es) 1983-08-16
YU196382A (en) 1985-03-20
FI78085B (fi) 1989-02-28
HU188328B (en) 1986-04-28
DE3270423D1 (en) 1986-05-15
PH17423A (en) 1984-08-08
PL238095A1 (en) 1984-03-26
EP0074229A1 (en) 1983-03-16
EP0074229B1 (en) 1986-04-09
GR77241B (pt) 1984-09-11
KR840001155A (ko) 1984-03-28
FI822999L (fi) 1983-03-01
AU534063B2 (en) 1984-01-05
ATE19078T1 (de) 1986-04-15
DK386882A (da) 1983-04-07
YU42795B (en) 1988-12-31
AR230994A1 (es) 1984-08-31
DK160303B (da) 1991-02-25
PL134315B1 (en) 1985-08-31
IE53586B1 (en) 1988-12-21

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Legal Events

Date Code Title Description
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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19920427