KR850000474B1 - 6β-[2-(2'-메틸페녹시카르보닐)-2-티엔-3'-일아세트아미도]페니실란산의 제조방법 - Google Patents
6β-[2-(2'-메틸페녹시카르보닐)-2-티엔-3'-일아세트아미도]페니실란산의 제조방법 Download PDFInfo
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- KR850000474B1 KR850000474B1 KR1019800003787A KR800003787A KR850000474B1 KR 850000474 B1 KR850000474 B1 KR 850000474B1 KR 1019800003787 A KR1019800003787 A KR 1019800003787A KR 800003787 A KR800003787 A KR 800003787A KR 850000474 B1 KR850000474 B1 KR 850000474B1
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- DBGVGMSCBYYSLD-UHFFFAOYSA-N tributylstannane Chemical compound CCCC[SnH](CCCC)CCCC DBGVGMSCBYYSLD-UHFFFAOYSA-N 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 230000036325 urinary excretion Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/72—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by carbon atoms having three bonds to hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/76—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with hetero rings directly attached to the carboxamido radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019840007607A KR850000473B1 (ko) | 1979-10-02 | 1984-12-03 | 6β-[2-(2'-메틸페녹시카르보닐)-2-티엔-3'-일아세트아미도]페니실란산의 제조방법 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB34062 | 1979-10-02 | ||
| GB7934062 | 1979-10-02 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019840007607A Division KR850000473B1 (ko) | 1979-10-02 | 1984-12-03 | 6β-[2-(2'-메틸페녹시카르보닐)-2-티엔-3'-일아세트아미도]페니실란산의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR830003498A KR830003498A (ko) | 1983-06-21 |
| KR850000474B1 true KR850000474B1 (ko) | 1985-04-08 |
Family
ID=10508217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019800003787A Expired KR850000474B1 (ko) | 1979-10-02 | 1980-09-30 | 6β-[2-(2'-메틸페녹시카르보닐)-2-티엔-3'-일아세트아미도]페니실란산의 제조방법 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4385060A (enExample) |
| EP (1) | EP0026644B1 (enExample) |
| JP (1) | JPS5659781A (enExample) |
| KR (1) | KR850000474B1 (enExample) |
| AR (1) | AR227953A1 (enExample) |
| AU (1) | AU534572B2 (enExample) |
| CA (1) | CA1148941A (enExample) |
| DE (1) | DE3061229D1 (enExample) |
| DK (1) | DK415780A (enExample) |
| ES (1) | ES8106733A1 (enExample) |
| FI (1) | FI803015A7 (enExample) |
| GR (1) | GR70283B (enExample) |
| HK (1) | HK786A (enExample) |
| HU (1) | HU182676B (enExample) |
| IE (1) | IE50508B1 (enExample) |
| IL (1) | IL61031A0 (enExample) |
| MY (1) | MY8600395A (enExample) |
| NO (1) | NO802910L (enExample) |
| NZ (1) | NZ194912A (enExample) |
| PH (1) | PH17119A (enExample) |
| PL (3) | PL129141B1 (enExample) |
| PT (1) | PT71856B (enExample) |
| SG (1) | SG72685G (enExample) |
| YU (2) | YU249080A (enExample) |
| ZA (1) | ZA805665B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL67672A0 (en) * | 1982-01-22 | 1983-05-15 | Beecham Group Plc | Penicillin derivatives,their preparation and pharmaceutical compositions containing them |
| CZ303537B6 (cs) | 2000-03-09 | 2012-11-21 | Gw Pharma Limited | Použití konopí pri príprave farmaceutické formulace a pumpickové sprejové zarízení |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853849A (en) * | 1969-05-29 | 1974-12-10 | Beecham Group Ltd | Alpha(aryloxycarbonyl)-and alpha(alkoxy-carbonyl)-aralkyl penicillins |
| GB1229670A (enExample) | 1968-09-03 | 1971-04-28 | ||
| BE759795A (fr) | 1969-12-11 | 1971-06-03 | Pfizer | Synthese de penicillines par l'intermediaire d'anhydrides mixtes de l'acide sulfurique |
| US4171303A (en) * | 1974-07-30 | 1979-10-16 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives |
| GB1455529A (enExample) | 1975-02-27 | 1976-11-10 | ||
| JO984B1 (en) | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
-
1980
- 1980-09-10 GR GR62854A patent/GR70283B/el unknown
- 1980-09-10 NZ NZ194912A patent/NZ194912A/xx unknown
- 1980-09-12 ZA ZA00805665A patent/ZA805665B/xx unknown
- 1980-09-14 IL IL61031A patent/IL61031A0/xx unknown
- 1980-09-22 US US06/189,622 patent/US4385060A/en not_active Expired - Lifetime
- 1980-09-25 FI FI803015A patent/FI803015A7/fi not_active Application Discontinuation
- 1980-09-26 EP EP80303378A patent/EP0026644B1/en not_active Expired
- 1980-09-26 DE DE8080303378T patent/DE3061229D1/de not_active Expired
- 1980-09-30 AU AU62830/80A patent/AU534572B2/en not_active Ceased
- 1980-09-30 KR KR1019800003787A patent/KR850000474B1/ko not_active Expired
- 1980-09-30 PT PT71856A patent/PT71856B/pt unknown
- 1980-09-30 YU YU02490/80A patent/YU249080A/xx unknown
- 1980-10-01 PL PL1980232295A patent/PL129141B1/pl unknown
- 1980-10-01 DK DK415780A patent/DK415780A/da unknown
- 1980-10-01 PL PL1980227022A patent/PL129153B1/pl unknown
- 1980-10-01 HU HU802394A patent/HU182676B/hu unknown
- 1980-10-01 CA CA000361314A patent/CA1148941A/en not_active Expired
- 1980-10-01 PL PL23229480A patent/PL232294A1/xx unknown
- 1980-10-01 ES ES495554A patent/ES8106733A1/es not_active Expired
- 1980-10-01 NO NO802910A patent/NO802910L/no unknown
- 1980-10-01 IE IE2045/80A patent/IE50508B1/en unknown
- 1980-10-02 JP JP13823280A patent/JPS5659781A/ja active Pending
- 1980-10-02 PH PH24658A patent/PH17119A/en unknown
-
1981
- 1981-12-21 AR AR287880A patent/AR227953A1/es active
-
1983
- 1983-02-25 YU YU00458/83A patent/YU45883A/xx unknown
-
1985
- 1985-10-05 SG SG726/85A patent/SG72685G/en unknown
-
1986
- 1986-01-02 HK HK7/86A patent/HK786A/xx unknown
- 1986-12-30 MY MY395/86A patent/MY8600395A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL232294A1 (enExample) | 1982-03-29 |
| DE3061229D1 (en) | 1983-01-05 |
| JPS5659781A (en) | 1981-05-23 |
| HK786A (en) | 1986-01-10 |
| AR227953A1 (es) | 1982-12-30 |
| PL232295A1 (enExample) | 1982-03-29 |
| NZ194912A (en) | 1983-05-31 |
| EP0026644A1 (en) | 1981-04-08 |
| PH17119A (en) | 1984-06-01 |
| EP0026644B1 (en) | 1982-12-01 |
| CA1148941A (en) | 1983-06-28 |
| PT71856B (en) | 1981-07-09 |
| YU249080A (en) | 1983-06-30 |
| KR830003498A (ko) | 1983-06-21 |
| GR70283B (enExample) | 1982-09-03 |
| MY8600395A (en) | 1986-12-31 |
| ZA805665B (en) | 1981-09-30 |
| PT71856A (en) | 1980-10-01 |
| YU45883A (en) | 1983-12-31 |
| IE50508B1 (en) | 1986-04-30 |
| ES495554A0 (es) | 1981-09-01 |
| NO802910L (no) | 1981-04-03 |
| IL61031A0 (en) | 1980-11-30 |
| FI803015A7 (fi) | 1981-01-01 |
| PL129153B1 (en) | 1984-04-30 |
| SG72685G (en) | 1986-05-02 |
| IE802045L (en) | 1981-04-02 |
| AU534572B2 (en) | 1984-02-09 |
| DK415780A (da) | 1981-04-03 |
| ES8106733A1 (es) | 1981-09-01 |
| AU6283080A (en) | 1981-04-09 |
| US4385060A (en) | 1983-05-24 |
| PL227022A1 (enExample) | 1981-12-11 |
| HU182676B (en) | 1984-02-28 |
| PL129141B1 (en) | 1984-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19800930 |
|
| PG1501 | Laying open of application | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19840202 Patent event code: PE09021S01D |
|
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19840901 Patent event code: PE09021S01D |
|
| PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19850305 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19850626 |