KR830006179A - 헤테로알킬렌비스 안트라퀴논 제조방법 - Google Patents

헤테로알킬렌비스 안트라퀴논 제조방법 Download PDF

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Publication number
KR830006179A
KR830006179A KR1019810002337A KR810002337A KR830006179A KR 830006179 A KR830006179 A KR 830006179A KR 1019810002337 A KR1019810002337 A KR 1019810002337A KR 810002337 A KR810002337 A KR 810002337A KR 830006179 A KR830006179 A KR 830006179A
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KR
South Korea
Prior art keywords
formula
iii
hydrogen
heteroalkylenebis
anthraquinone process
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Application number
KR1019810002337A
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English (en)
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KR840001309B1 (ko
Inventor
채드윅크 머독크 키이쓰
Original Assignee
죤 제이 헤이간
아메리칸 사이아나밋드 캄파니
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Application filed by 죤 제이 헤이간, 아메리칸 사이아나밋드 캄파니 filed Critical 죤 제이 헤이간
Publication of KR830006179A publication Critical patent/KR830006179A/ko
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Publication of KR840001309B1 publication Critical patent/KR840001309B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F5/00—Softening water; Preventing scale; Adding scale preventatives or scale removers to water, e.g. adding sequestering agents
    • C02F5/08—Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents
    • C02F5/10—Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents using organic substances
    • C02F5/12—Treatment of water with complexing chemicals or other solubilising agents for softening, scale prevention or scale removal, e.g. adding sequestering agents using organic substances containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/24—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/24—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • C07C225/26—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hydrology & Water Resources (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Environmental & Geological Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

헤테로알킬렌비스 안트라퀴논 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 일반식(가)의 류코 퀴니자린 약 2몰과 일반식(나)(NH2-A-NA2)의 헤테로알킬렌디아민을 비활성 용매중에서 약 5-50℃에서 축합시켜 일반식(다)의 1,1'-비스류코 중간체를 제조한 후 비활성 용매중에서 일반식(라)의 알킬렌디아민과 약 40-60℃에서 비활성분위기하에서 축합시켜 얻은 류코염기를 산화시키므로서 일반식(마)의 화합물을 제조하는 방법.
    (U와 V는 같거나 상이한 것으로서 각각 2-5의 정수)이고, R은 수소 및 히드록시, R1과 R2는 각각 질소원자에 대한 알파탄소가 히드록시기를 가지지 않는 탄소원자를 2-4개 가진 모노히드록시알킬, 탄소원자수가 1-4인 알킬 및 수소로 된 기이며, R3는 수소 또는 저급 알킬(C1-C3)임.
    (ⅱ) 일반식 (가)에서 R는 (ⅰ)에서 정의된 바와 같음.
    (ⅲ) 일반식 (나)에서 A는 (ⅰ)에서 정의된 바와 같음.
    (ⅳ) 일반식 (다)에서 R과 A는 (ⅰ)에서 정의된 바와 같음.
    (ⅴ) 일반식 (라)에서 R1과 R2및 Q는 (ⅰ)에서 정의된 바와 같음.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810002337A 1980-06-30 1981-06-29 헤테로알킬렌비스 안트라퀴논 제조방법 KR840001309B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/164,615 US4278605A (en) 1980-06-30 1980-06-30 Heteroalkylenebisanthraquinones
US164,615 1980-06-30
US164615 1998-10-01

Publications (2)

Publication Number Publication Date
KR830006179A true KR830006179A (ko) 1983-09-20
KR840001309B1 KR840001309B1 (ko) 1984-09-11

Family

ID=22595305

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002337A KR840001309B1 (ko) 1980-06-30 1981-06-29 헤테로알킬렌비스 안트라퀴논 제조방법

Country Status (7)

Country Link
US (1) US4278605A (ko)
EP (1) EP0042940B1 (ko)
JP (1) JPS5785345A (ko)
KR (1) KR840001309B1 (ko)
CA (1) CA1169057A (ko)
DE (1) DE3163961D1 (ko)
NZ (1) NZ197556A (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083683A1 (en) * 1981-10-26 1983-07-20 American Cyanamid Company Method of preparing 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones and pharmaceutical compositions containing them
DE3574932D1 (de) * 1984-02-27 1990-02-01 American Cyanamid Co Verwendung von 1,4 bisubstituierten anthrachinonen zur herstellung von immunsuppressiva.
GB8923075D0 (en) * 1989-10-13 1989-11-29 Patterson Laurence H Anti-cancer compounds
IT1237506B (it) * 1989-10-27 1993-06-08 Boehringer Biochemia Srl Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali
ATE169614T1 (de) * 1993-12-27 1998-08-15 Ciba Geigy Ag Ungesättigte aminoverbindungen zur verwendung als antikrebsmittel und als mittelgegen protozoen
GB2318349A (en) * 1996-10-15 1998-04-22 Gyre Ltd Biocidal composition for wet environment
US7851172B2 (en) * 2006-07-25 2010-12-14 University Of Kentucky Research Foundation Biomarkers of mild cognitive impairment and alzheimer's disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1028717B (de) * 1955-01-22 1958-04-24 Basf Ag Verfahren zur Herstellung von Anthrachinonfarbstoffen
FR1529724A (fr) * 1967-04-21 1968-06-21 Ugine Kuhlmann Nouveaux colorants anthraquinoniques et intermédiaires pour leur préparation
US4027021A (en) * 1974-08-23 1977-05-31 The Upjohn Company Interferon induction
DE2722507A1 (de) * 1977-05-18 1978-11-23 Allied Chem Anthrachinonderivate
US4197249A (en) * 1977-08-15 1980-04-08 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
SE445996B (sv) * 1977-08-15 1986-08-04 American Cyanamid Co Nya atrakinonderivat

Also Published As

Publication number Publication date
JPH0243728B2 (ko) 1990-10-01
JPS5785345A (en) 1982-05-28
EP0042940A1 (en) 1982-01-06
KR840001309B1 (ko) 1984-09-11
NZ197556A (en) 1983-09-30
DE3163961D1 (de) 1984-07-12
EP0042940B1 (en) 1984-06-06
CA1169057A (en) 1984-06-12
US4278605A (en) 1981-07-14

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