ATE169614T1 - Ungesättigte aminoverbindungen zur verwendung als antikrebsmittel und als mittelgegen protozoen - Google Patents

Ungesättigte aminoverbindungen zur verwendung als antikrebsmittel und als mittelgegen protozoen

Info

Publication number
ATE169614T1
ATE169614T1 AT95903819T AT95903819T ATE169614T1 AT E169614 T1 ATE169614 T1 AT E169614T1 AT 95903819 T AT95903819 T AT 95903819T AT 95903819 T AT95903819 T AT 95903819T AT E169614 T1 ATE169614 T1 AT E169614T1
Authority
AT
Austria
Prior art keywords
pct
carbon atom
bonding
nitrogen
anticancer
Prior art date
Application number
AT95903819T
Other languages
English (en)
Inventor
Joerg Frei
Jaroslav Stanek
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of ATE169614T1 publication Critical patent/ATE169614T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/22Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/23Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton the carbon skeleton containing carbon-to-carbon triple bonds

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
AT95903819T 1993-12-27 1994-12-14 Ungesättigte aminoverbindungen zur verwendung als antikrebsmittel und als mittelgegen protozoen ATE169614T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH387693 1993-12-27

Publications (1)

Publication Number Publication Date
ATE169614T1 true ATE169614T1 (de) 1998-08-15

Family

ID=4265390

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95903819T ATE169614T1 (de) 1993-12-27 1994-12-14 Ungesättigte aminoverbindungen zur verwendung als antikrebsmittel und als mittelgegen protozoen

Country Status (13)

Country Link
US (1) US5627215A (de)
EP (1) EP0686143B1 (de)
JP (1) JPH08507548A (de)
CN (1) CN1121707A (de)
AT (1) ATE169614T1 (de)
AU (1) AU690618B2 (de)
BR (1) BR9405892A (de)
CA (1) CA2155095A1 (de)
DE (1) DE69412467T2 (de)
DK (1) DK0686143T3 (de)
ES (1) ES2119371T3 (de)
NZ (1) NZ277503A (de)
WO (1) WO1995018091A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184232B1 (en) * 1986-12-02 2001-02-06 University Of Florida Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
DE69711413T2 (de) * 1996-10-18 2002-07-18 Wisconsin Alumni Research Foundation, Madison In ihrer konformation eingeschränkte polyamine und ihre verwendung als antineoplastische mittel
US5889061A (en) * 1997-10-15 1999-03-30 Wisconsin Alumni Research Foundation Conformationally restricted polyamines
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
AU4679900A (en) * 1999-04-30 2000-11-17 Slil Biomedical Corporation Conformationally restricted polyamine analogs as disease therapies
JP2002543163A (ja) * 1999-04-30 2002-12-17 スリル バイオメディカル コーポレイション 癌および前立腺疾患のための治療としての結合体
JP2004513136A (ja) * 2000-11-08 2004-04-30 スリル バイオメディカル コーポレーション 抗癌剤として有用な新規ポリアミンアナログ−アミノ酸結合体
EP1436246A1 (de) 2001-10-16 2004-07-14 SLIL Biomedical Corporation Oligoamin-verbindungen und ihre derivate für die krebstherapie
EP1453787A1 (de) 2001-12-07 2004-09-08 SLIL Biomedical Corporation Zykloalkyl-substituierte polyamine zur krebstherapie und verfahren zur deren herstellung
AU2003210883A1 (en) * 2002-02-07 2003-09-02 Wisconsin Alumni Research Foundation Polyamine compounds and compositions for use in conjunction with cancer therapy
WO2005014524A2 (en) * 2003-08-07 2005-02-17 Wisconsin Alumni Research Foundation Amino thiol compounds and compositions for use in conjunction with cancer therapy
KR101050328B1 (ko) 2004-08-31 2011-07-19 엘지디스플레이 주식회사 램프 및 이를 구비한 백라이트 구동장치
BRPI0614805A2 (pt) * 2005-08-10 2011-04-12 Univ Johns Hopkins poliaminas úteis como produtos terapêuticos antiparasìticos e anticáncer e como inibidores de demetilase lisina-especìficos
WO2011097317A1 (en) * 2010-02-02 2011-08-11 Progen Pharmaceuticals, Inc. Use of n1,n4-bis[3-(ethylamino)propyl]-2-butene-1,4-diamine compounds in combination with epigenetic-acting pharmaceuticals for enhanced cancer therapy
CN102212013A (zh) * 2011-03-30 2011-10-12 广东中科药物研究有限公司 一种多胺化合物及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2991290A (en) * 1957-03-20 1961-07-04 Us Vitamin Corp Nu-alkylamino-alpha-hydroxy-alkanoic acid amides
US4278605A (en) * 1980-06-30 1981-07-14 American Cyanamid Company Heteroalkylenebisanthraquinones
CA1305425C (en) * 1986-12-02 1992-07-21 Raymond J. Bergeron Anti-neoplastic spermine derivative
US5091576A (en) * 1986-12-02 1992-02-25 University Of Florida Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
NZ223340A (en) * 1987-02-03 1991-03-26 Merrell Dow Pharma Polyamine derivatives and pharmaceutical compositions
US4935449A (en) * 1988-08-04 1990-06-19 Merrell Dow Pharmaceuticals Inc. N-2,3-butadienyl tri- and tetraaminoalkane derivatives
JPH02118405A (ja) * 1988-10-27 1990-05-02 Nec Yamagata Ltd 微小寸法測定装置
GB9115375D0 (en) * 1991-07-17 1991-09-04 Salutar Inc Compounds

Also Published As

Publication number Publication date
EP0686143A1 (de) 1995-12-13
US5627215A (en) 1997-05-06
WO1995018091A1 (en) 1995-07-06
EP0686143B1 (de) 1998-08-12
BR9405892A (pt) 1995-12-12
AU1274495A (en) 1995-07-17
DE69412467D1 (de) 1998-09-17
ES2119371T3 (es) 1998-10-01
NZ277503A (en) 1997-07-27
DK0686143T3 (da) 1999-05-17
CA2155095A1 (en) 1995-07-06
JPH08507548A (ja) 1996-08-13
CN1121707A (zh) 1996-05-01
DE69412467T2 (de) 1999-01-28
AU690618B2 (en) 1998-04-30

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee