DK0984980T3 - 20-aralkyl-5alfa-pregnan-derivater - Google Patents

20-aralkyl-5alfa-pregnan-derivater

Info

Publication number
DK0984980T3
DK0984980T3 DK98924316T DK98924316T DK0984980T3 DK 0984980 T3 DK0984980 T3 DK 0984980T3 DK 98924316 T DK98924316 T DK 98924316T DK 98924316 T DK98924316 T DK 98924316T DK 0984980 T3 DK0984980 T3 DK 0984980T3
Authority
DK
Denmark
Prior art keywords
alkyl
alkoxy
hydroxy
halogen
independently hydrogen
Prior art date
Application number
DK98924316T
Other languages
English (en)
Inventor
Johannes Antonius Jos Leemhuis
Der Louw Jaap Van
Marinus Bernard Groen
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK0984980T3 publication Critical patent/DK0984980T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK98924316T 1997-05-16 1998-05-11 20-aralkyl-5alfa-pregnan-derivater DK0984980T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201474 1997-05-16
PCT/EP1998/002989 WO1998052965A1 (en) 1997-05-16 1998-05-11 20-ARALKYL-5α-PREGNANE DERIVATIVES

Publications (1)

Publication Number Publication Date
DK0984980T3 true DK0984980T3 (da) 2003-03-17

Family

ID=8228325

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98924316T DK0984980T3 (da) 1997-05-16 1998-05-11 20-aralkyl-5alfa-pregnan-derivater

Country Status (17)

Country Link
US (1) US6177420B1 (da)
EP (1) EP0984980B1 (da)
JP (1) JP2001526673A (da)
KR (1) KR20010012643A (da)
CN (1) CN1260802A (da)
AT (1) ATE229032T1 (da)
AU (1) AU726016B2 (da)
BR (1) BR9808803A (da)
CA (1) CA2289675A1 (da)
DE (1) DE69809905T2 (da)
DK (1) DK0984980T3 (da)
ES (1) ES2189173T3 (da)
HU (1) HUP0002331A3 (da)
NO (1) NO995590L (da)
PL (1) PL337008A1 (da)
TR (1) TR199902793T2 (da)
WO (1) WO1998052965A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1042353B1 (en) 1997-12-18 2002-07-17 Akzo Nobel N.V. 17beta-aryl (arylmethyl) oxy(thio)alkyl -androstane derivatives
PL344155A1 (en) * 1998-05-13 2001-10-08 Novo Nordisk As Meiosis regulating compounds
EP1087988A1 (en) * 1998-06-19 2001-04-04 Novo Nordisk A/S Meiosis regulating compounds
ATE392899T1 (de) * 1999-03-02 2008-05-15 Organon Nv (androst-5-en-17beta-yl)alkyl sulfoxide und sulfone und deren verwendung zur kontrolle der fruchtbarkeit
AU5209600A (en) * 1999-04-06 2000-10-23 Akzo Nobel N.V. Orally active androgens
EP1127890A1 (en) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments
US6988613B2 (en) * 2001-02-06 2006-01-24 Novo Nordisk A/S Composition for IVF
US9532994B2 (en) 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
CA2553815A1 (en) 2004-01-15 2005-08-04 Warner Chilcott Company, Inc. Di-steroidal prodrugs of estradiol
MXPA06007851A (es) 2004-01-15 2007-01-31 Warner Chilcott Co Inc Profarmacos di-esteroidales de etinil estradiol.
EP1910401A2 (en) 2005-07-12 2008-04-16 Warner Chilcott Company, Inc. 3-ester prodrugs of ethynylestradiol
EP1993558B1 (en) 2006-02-27 2014-07-30 The Regents of The University of California Oxysterol compounds and the hedgehog pathway
AU2008331808B2 (en) 2007-03-16 2014-08-21 The Regents Of The University Of California Oxysterols for activation of hedgehog signaling, osteoinduction, antiadipogenesis, and Wnt signaling
CA2872751A1 (en) 2012-05-07 2013-11-14 The Regents Of The University Of California Oxysterol analogue oxy133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
CN105263500A (zh) 2013-05-02 2016-01-20 加利福尼亚大学董事会 骨选择性成骨性氧固醇-骨靶向剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
WO1996027658A1 (en) * 1995-03-06 1996-09-12 Novo Nordisk A/S Stimulation of meiosis
CN1191543A (zh) 1995-06-23 1998-08-26 诺沃挪第克公司 减数分裂调控化合物

Also Published As

Publication number Publication date
ES2189173T3 (es) 2003-07-01
HUP0002331A3 (en) 2001-05-28
CA2289675A1 (en) 1998-11-26
AU726016B2 (en) 2000-10-26
DE69809905D1 (de) 2003-01-16
ATE229032T1 (de) 2002-12-15
JP2001526673A (ja) 2001-12-18
NO995590L (no) 2000-01-11
BR9808803A (pt) 2000-07-18
NO995590D0 (no) 1999-11-15
TR199902793T2 (xx) 2000-06-21
DE69809905T2 (de) 2003-08-28
WO1998052965A1 (en) 1998-11-26
HUP0002331A2 (hu) 2000-12-28
AU7654998A (en) 1998-12-11
EP0984980B1 (en) 2002-12-04
US6177420B1 (en) 2001-01-23
EP0984980A1 (en) 2000-03-15
CN1260802A (zh) 2000-07-19
KR20010012643A (ko) 2001-02-26
PL337008A1 (en) 2000-07-31

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