KR20230083294A - 폴리펩타이드 접합체 및 사용 방법 - Google Patents
폴리펩타이드 접합체 및 사용 방법 Download PDFInfo
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- KR20230083294A KR20230083294A KR1020237013534A KR20237013534A KR20230083294A KR 20230083294 A KR20230083294 A KR 20230083294A KR 1020237013534 A KR1020237013534 A KR 1020237013534A KR 20237013534 A KR20237013534 A KR 20237013534A KR 20230083294 A KR20230083294 A KR 20230083294A
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- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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| CN2021099030 | 2021-06-09 | ||
| CNPCT/CN2021/099030 | 2021-06-09 | ||
| PCT/CN2021/122075 WO2022068920A1 (en) | 2020-09-30 | 2021-09-30 | Polypeptide conjugates and methods of uses |
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| EP (1) | EP4222176A4 (https=) |
| JP (1) | JP2023545684A (https=) |
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| CN114729060B (zh) * | 2020-09-30 | 2022-11-25 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
| WO2022159395A1 (en) | 2021-01-20 | 2022-07-28 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| MX2024003236A (es) | 2021-09-15 | 2024-06-19 | Viking Therapeutics Inc | Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos. |
| WO2023179796A1 (en) * | 2022-03-25 | 2023-09-28 | Beijing Ql Biopharmaceutical Co., Ltd. | Pharmaceutical compositions of polypeptide conjugates and methods of uses thereof |
| WO2023186003A1 (en) * | 2022-03-30 | 2023-10-05 | Beijing Ql Biopharmaceutical Co., Ltd. | Liquid pharmaceutical compositions of polypeptide conjugates and methods of uses thereof |
| EP4323413A4 (en) * | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
| WO2025185605A1 (en) * | 2024-03-05 | 2025-09-12 | Beijing Ql Biopharmaceutical Co., Ltd. | Polypeptide conjugates and methods of uses |
| WO2026008836A1 (en) * | 2024-07-05 | 2026-01-08 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
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| CN114729060B (zh) * | 2020-09-30 | 2022-11-25 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
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| EP4222176A1 (en) | 2023-08-09 |
| EP4222176A4 (en) | 2024-02-28 |
| JP2023545684A (ja) | 2023-10-31 |
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| CN114729060A (zh) | 2022-07-08 |
| US20220133856A1 (en) | 2022-05-05 |
| US11529394B2 (en) | 2022-12-20 |
| CN115925994B (zh) | 2023-09-22 |
| CA3193453A1 (en) | 2022-04-07 |
| CN115925995A (zh) | 2023-04-07 |
| US20240181016A1 (en) | 2024-06-06 |
| CN114729060B (zh) | 2022-11-25 |
| WO2022068920A1 (en) | 2022-04-07 |
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