KR20220025922A - 멀티플렉스 rna-가이드된 게놈 조작 - Google Patents

멀티플렉스 rna-가이드된 게놈 조작 Download PDF

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KR20220025922A
KR20220025922A KR1020227004950A KR20227004950A KR20220025922A KR 20220025922 A KR20220025922 A KR 20220025922A KR 1020227004950 A KR1020227004950 A KR 1020227004950A KR 20227004950 A KR20227004950 A KR 20227004950A KR 20220025922 A KR20220025922 A KR 20220025922A
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죠지 엠. 처치
제임스 디카를로
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프레지던트 앤드 펠로우즈 오브 하바드 칼리지
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]

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KR1020227004950A 2013-07-09 2014-07-08 멀티플렉스 rna-가이드된 게놈 조작 Ceased KR20220025922A (ko)

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KR1020237027175A KR20230122182A (ko) 2013-07-09 2014-07-08 멀티플렉스 rna-가이드된 게놈 조작

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361844168P 2013-07-09 2013-07-09
US61/844,168 2013-07-09
PCT/US2014/045691 WO2015006290A1 (en) 2013-07-09 2014-07-08 Multiplex rna-guided genome engineering
KR1020167003073A KR20160029112A (ko) 2013-07-09 2014-07-08 멀티플렉스 rna-가이드된 게놈 조작

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KR1020167003073A Ceased KR20160029112A (ko) 2013-07-09 2014-07-08 멀티플렉스 rna-가이드된 게놈 조작
KR1020237027175A Pending KR20230122182A (ko) 2013-07-09 2014-07-08 멀티플렉스 rna-가이드된 게놈 조작

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KR1020237027175A Pending KR20230122182A (ko) 2013-07-09 2014-07-08 멀티플렉스 rna-가이드된 게놈 조작

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US (2) US11459585B2 (enExample)
EP (2) EP4166669A1 (enExample)
JP (4) JP7120717B2 (enExample)
KR (3) KR20220025922A (enExample)
CN (2) CN116042726A (enExample)
AU (3) AU2014287393B2 (enExample)
CA (2) CA2917638C (enExample)
ES (1) ES2929143T3 (enExample)
IL (2) IL303973A (enExample)
RU (2) RU2706562C2 (enExample)
SG (3) SG10201913026TA (enExample)
WO (1) WO2015006290A1 (enExample)

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