KR20220004053A - 항-cgrp 항체를 사용하는 두통의 치료 - Google Patents

항-cgrp 항체를 사용하는 두통의 치료 Download PDF

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Publication number
KR20220004053A
KR20220004053A KR1020217035290A KR20217035290A KR20220004053A KR 20220004053 A KR20220004053 A KR 20220004053A KR 1020217035290 A KR1020217035290 A KR 1020217035290A KR 20217035290 A KR20217035290 A KR 20217035290A KR 20220004053 A KR20220004053 A KR 20220004053A
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Prior art keywords
administration
seq
migraine
hours
antibody
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Pending
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KR1020217035290A
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Korean (ko)
Inventor
로저 케이 케이디
제프리 티 엘 스미스
조셉 허먼
바바라 쉐플러
라하르 메타
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하. 룬드벡 아크티에셀스카브
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Priority claimed from PCT/US2020/012781 external-priority patent/WO2020146527A1/en
Application filed by 하. 룬드벡 아크티에셀스카브 filed Critical 하. 룬드벡 아크티에셀스카브
Publication of KR20220004053A publication Critical patent/KR20220004053A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020217035290A 2019-05-02 2020-02-18 항-cgrp 항체를 사용하는 두통의 치료 Pending KR20220004053A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962842162P 2019-05-02 2019-05-02
US62/842,162 2019-05-02
US201962872989P 2019-07-11 2019-07-11
US62/872,989 2019-07-11
PCT/US2020/012781 WO2020146527A1 (en) 2019-01-08 2020-01-08 Acute treatment and rapid treatment of headache using anti-cgrp antibodies
USPCT/US2020/012781 2020-01-08
PCT/US2020/018702 WO2020222892A1 (en) 2019-05-02 2020-02-18 Treatment of headache using anti-cgrp antibodies

Publications (1)

Publication Number Publication Date
KR20220004053A true KR20220004053A (ko) 2022-01-11

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217035290A Pending KR20220004053A (ko) 2019-05-02 2020-02-18 항-cgrp 항체를 사용하는 두통의 치료

Country Status (20)

Country Link
US (1) US12630614B2 (cg-RX-API-DMAC10.html)
EP (1) EP3962522A4 (cg-RX-API-DMAC10.html)
JP (2) JP2022533030A (cg-RX-API-DMAC10.html)
KR (1) KR20220004053A (cg-RX-API-DMAC10.html)
CN (1) CN113811326A (cg-RX-API-DMAC10.html)
AU (2) AU2020267107B2 (cg-RX-API-DMAC10.html)
BR (1) BR112020027063A2 (cg-RX-API-DMAC10.html)
CA (1) CA3133571A1 (cg-RX-API-DMAC10.html)
CL (1) CL2021002866A1 (cg-RX-API-DMAC10.html)
DO (1) DOP2021000215A (cg-RX-API-DMAC10.html)
EA (1) EA202192865A1 (cg-RX-API-DMAC10.html)
GE (2) GEAP202515803A (cg-RX-API-DMAC10.html)
IL (1) IL287759A (cg-RX-API-DMAC10.html)
JO (1) JOP20210247A1 (cg-RX-API-DMAC10.html)
MA (1) MA55815A (cg-RX-API-DMAC10.html)
MX (1) MX2021013426A (cg-RX-API-DMAC10.html)
PH (1) PH12021552422A1 (cg-RX-API-DMAC10.html)
SG (1) SG11202110637RA (cg-RX-API-DMAC10.html)
WO (1) WO2020222892A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA202106627B (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEAP202515803A (en) 2019-05-02 2025-06-10 H Lundbeck As Treatment of headache using anti-cgrp antibodies
CN117813325A (zh) * 2021-08-27 2024-04-02 H.隆德贝克有限公司 使用抗cgrp抗体治疗丛集性头痛
MX2024002340A (es) 2021-09-15 2024-03-07 H Lundbeck As Metodos de administracion y seleccion de anticuerpos anti-cgrp.

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JP2022533030A (ja) 2022-07-21
IL287759A (en) 2022-01-01
ZA202106627B (en) 2025-12-17
EA202192865A1 (ru) 2022-02-14
PH12021552422A1 (en) 2022-07-11
US20220251178A1 (en) 2022-08-11
CA3133571A1 (en) 2020-11-05
MX2021013426A (es) 2021-12-10
GEAP202515803A (en) 2025-06-10
CN113811326A (zh) 2021-12-17
DOP2021000215A (es) 2021-11-21
US12630614B2 (en) 2026-05-19
SG11202110637RA (en) 2021-10-28
GEP20257803B (en) 2025-10-10
AU2026202964A1 (en) 2026-05-07
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