KR20210113273A - HIF-2 알파 (EPAS1)의 발현을 억제하기 위한 RNAi 작용제, 그의 조성물, 및 사용 방법 - Google Patents

HIF-2 알파 (EPAS1)의 발현을 억제하기 위한 RNAi 작용제, 그의 조성물, 및 사용 방법 Download PDF

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KR20210113273A
KR20210113273A KR1020217024646A KR20217024646A KR20210113273A KR 20210113273 A KR20210113273 A KR 20210113273A KR 1020217024646 A KR1020217024646 A KR 1020217024646A KR 20217024646 A KR20217024646 A KR 20217024646A KR 20210113273 A KR20210113273 A KR 20210113273A
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rnai agent
sense strand
nucleotides
hif
alpha
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전 리
동쉬 수
앤쏘니 니콜라스
루이 주
제프리 칼슨
소 웡
샤오카이 리
에리히 알텐호퍼
매튜 파울러-워터스
보 천
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애로우헤드 파마슈티컬스 인코포레이티드
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KR1020217024646A 2019-01-09 2020-01-08 HIF-2 알파 (EPAS1)의 발현을 억제하기 위한 RNAi 작용제, 그의 조성물, 및 사용 방법 Ceased KR20210113273A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962790360P 2019-01-09 2019-01-09
US62/790,360 2019-01-09
US201962827564P 2019-04-01 2019-04-01
US62/827,564 2019-04-01
US201962839381P 2019-04-26 2019-04-26
US62/839,381 2019-04-26
PCT/US2020/012775 WO2020146521A2 (en) 2019-01-09 2020-01-08 Rnai agents for inhibiting expression of hif-2 alpha (epas1), compositions thereof, and methods of use

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KR20210113273A true KR20210113273A (ko) 2021-09-15

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US (1) US12221610B2 (https=)
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KR (1) KR20210113273A (https=)
CN (1) CN113613661B (https=)
AU (1) AU2020207050A1 (https=)
BR (1) BR112021013362A2 (https=)
CA (1) CA3120580A1 (https=)
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CN116323633A (zh) * 2020-09-11 2023-06-23 箭头药业股份有限公司 骨骼肌递送平台及使用方法
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CN115105607B (zh) * 2021-03-22 2024-12-20 成都科岭源医药技术有限公司 一种用于adc的双药-接头的制备方法及其用途
CN113304274B (zh) * 2021-04-23 2025-03-04 天津全和诚生物技术有限公司 缀合物及其制备方法和用途
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