KR20200070236A - 면역치료제로서의 pd1-특이적 키메라 항원 수용체 - Google Patents
면역치료제로서의 pd1-특이적 키메라 항원 수용체 Download PDFInfo
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- KR20200070236A KR20200070236A KR1020207009640A KR20207009640A KR20200070236A KR 20200070236 A KR20200070236 A KR 20200070236A KR 1020207009640 A KR1020207009640 A KR 1020207009640A KR 20207009640 A KR20207009640 A KR 20207009640A KR 20200070236 A KR20200070236 A KR 20200070236A
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022211376A1 (ko) * | 2021-04-01 | 2022-10-06 | 주식회사 이뮤노로지컬디자이닝랩 | 키메릭 항원 수용체(car)를 포함하는 형질전환된 항원 특이적 전문적 항원표출세포 및 이의 용도 |
| WO2022220433A1 (ko) * | 2021-04-16 | 2022-10-20 | 주식회사 이뮤노로지컬디자이닝랩 | Programmed death-ligand 1(pd-l1)에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20180019725A (ko) * | 2015-06-23 | 2018-02-26 | 메모리얼 슬로안-케터링 캔서 센터 | 신규의 피디 1 면역 조절제 |
| WO2019067504A1 (en) | 2017-09-26 | 2019-04-04 | Longwood University | SPECIFIC CHIMERIC ANTIGEN RECEPTOR AT PD-1 AS IMMUNOTHERAPY |
| KR20230010228A (ko) * | 2020-05-08 | 2023-01-18 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 자연 살해 세포를 표적으로 하는 키메라 항원 수용체 (cars) |
| CA3240185A1 (en) * | 2021-12-06 | 2023-06-15 | Vycellix, Inc. | Chimeric switch receptors in nk cells |
| EP4551246A1 (en) | 2022-07-05 | 2025-05-14 | Neomics Pharmaceuticals LLC | Chimeric antigen receptor comprising bcma nanobody linked to a chimeric intracellular signaling domain |
| CN118359727A (zh) * | 2023-01-17 | 2024-07-19 | 上海以慈生物科技有限公司 | 突变的pd1胞外域片段及含有该片段的car和nk细胞 |
| WO2025059162A1 (en) | 2023-09-11 | 2025-03-20 | Dana-Farber Cancer Institute, Inc. | Car-engager containing il-2 variants to enhance the functionality of car t cells |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| EA201490364A1 (ru) * | 2011-07-29 | 2014-08-29 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Костимулирующие рецепторы-переключатели |
| JP6788573B6 (ja) * | 2014-04-10 | 2020-12-16 | シアトル チルドレンズ ホスピタル, ディービーエー シアトル チルドレンズ リサーチ インスティテュート | メトトレキサートによる選択と組み合わせたSleeping Beautyトランスポゾンによる遺伝子改変T細胞の製造 |
| US10479975B2 (en) * | 2014-06-06 | 2019-11-19 | Bluebird Bio, Inc. | Methods of making T cell compositions |
| WO2016028896A1 (en) | 2014-08-19 | 2016-02-25 | Novartis Ag | Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment |
| BR122021000068A8 (pt) * | 2014-10-27 | 2023-05-02 | Hutchinson Fred Cancer Res | Composições e usos em métodos para estimular a eficácia de imunoterapia celular adotiva |
| EP3089761B1 (en) * | 2015-03-02 | 2019-06-12 | Innovative Cellular Therapeutics Co., Ltd. | Reducing immune tolerance induced by pd l1 |
| CN106350533B (zh) * | 2015-10-09 | 2020-07-17 | 上海宇研生物技术有限公司 | Anti-PD-L1-CAR-T及其制备方法和应用 |
| AU2016341966A1 (en) * | 2015-10-20 | 2018-05-10 | Kite Pharma, Inc. | Methods of preparing T cells for T cell therapy |
| CN106399255B (zh) * | 2016-04-13 | 2019-10-18 | 阿思科力(苏州)生物科技有限公司 | Pd-1 car-t细胞及其制备方法和应用 |
| IL320149A (en) | 2017-03-16 | 2025-06-01 | Alpine Immune Sciences Inc | Pd-l1 variant immunomodulatory proteins and uses thereof |
| WO2019067504A1 (en) | 2017-09-26 | 2019-04-04 | Longwood University | SPECIFIC CHIMERIC ANTIGEN RECEPTOR AT PD-1 AS IMMUNOTHERAPY |
| CN108384795A (zh) * | 2017-10-13 | 2018-08-10 | 江苏西迪尔生物技术有限公司 | 作用于tme免疫效应细胞的人工合成基因及验证方法和应用 |
-
2018
- 2018-09-26 WO PCT/US2018/052799 patent/WO2019067504A1/en not_active Ceased
- 2018-09-26 US US16/650,884 patent/US11559549B2/en active Active
- 2018-09-26 CN CN201880075793.XA patent/CN111433354A/zh active Pending
- 2018-09-26 AU AU2018339528A patent/AU2018339528A1/en not_active Abandoned
- 2018-09-26 EP EP18862531.3A patent/EP3688143A4/en not_active Withdrawn
- 2018-09-26 KR KR1020207009640A patent/KR20200070236A/ko not_active Ceased
- 2018-09-26 JP JP2020518645A patent/JP2020536531A/ja active Pending
- 2018-09-26 MX MX2020007357A patent/MX2020007357A/es unknown
- 2018-09-26 CA CA3077187A patent/CA3077187A1/en active Pending
-
2022
- 2022-12-29 US US18/147,879 patent/US20230293583A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022211376A1 (ko) * | 2021-04-01 | 2022-10-06 | 주식회사 이뮤노로지컬디자이닝랩 | 키메릭 항원 수용체(car)를 포함하는 형질전환된 항원 특이적 전문적 항원표출세포 및 이의 용도 |
| WO2022220433A1 (ko) * | 2021-04-16 | 2022-10-20 | 주식회사 이뮤노로지컬디자이닝랩 | Programmed death-ligand 1(pd-l1)에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111433354A (zh) | 2020-07-17 |
| WO2019067504A1 (en) | 2019-04-04 |
| CA3077187A1 (en) | 2019-04-04 |
| US20230293583A1 (en) | 2023-09-21 |
| JP2020536531A (ja) | 2020-12-17 |
| MX2020007357A (es) | 2021-08-11 |
| US11559549B2 (en) | 2023-01-24 |
| AU2018339528A1 (en) | 2020-04-16 |
| EP3688143A1 (en) | 2020-08-05 |
| US20200281974A1 (en) | 2020-09-10 |
| EP3688143A4 (en) | 2021-09-22 |
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