KR20200065012A - 글리신 뇌병증 치료를 위한 벤조에이트 함유 조성물의 사용 - Google Patents

글리신 뇌병증 치료를 위한 벤조에이트 함유 조성물의 사용 Download PDF

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Publication number
KR20200065012A
KR20200065012A KR1020207011606A KR20207011606A KR20200065012A KR 20200065012 A KR20200065012 A KR 20200065012A KR 1020207011606 A KR1020207011606 A KR 1020207011606A KR 20207011606 A KR20207011606 A KR 20207011606A KR 20200065012 A KR20200065012 A KR 20200065012A
Authority
KR
South Korea
Prior art keywords
way
glyceryl
patient
pharmaceutical composition
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020207011606A
Other languages
English (en)
Korean (ko)
Inventor
칼리파다 파한
Original Assignee
러쉬 유니버시티 메디컬 센터
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 러쉬 유니버시티 메디컬 센터 filed Critical 러쉬 유니버시티 메디컬 센터
Publication of KR20200065012A publication Critical patent/KR20200065012A/ko
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020207011606A 2017-10-06 2018-09-26 글리신 뇌병증 치료를 위한 벤조에이트 함유 조성물의 사용 Ceased KR20200065012A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762569251P 2017-10-06 2017-10-06
US62/569,251 2017-10-06
PCT/US2018/052879 WO2019070478A1 (en) 2017-10-06 2018-09-26 USE OF A BENZOATE-CONTAINING COMPOSITION FOR TREATING GLYCINIC ENCEPHALOPATHY

Publications (1)

Publication Number Publication Date
KR20200065012A true KR20200065012A (ko) 2020-06-08

Family

ID=65994915

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207011606A Ceased KR20200065012A (ko) 2017-10-06 2018-09-26 글리신 뇌병증 치료를 위한 벤조에이트 함유 조성물의 사용

Country Status (10)

Country Link
US (1) US11304923B2 (https=)
EP (1) EP3691630A4 (https=)
JP (1) JP2020536098A (https=)
KR (1) KR20200065012A (https=)
CN (1) CN111212637A (https=)
AU (2) AU2018345244A1 (https=)
BR (1) BR112020005856A2 (https=)
CA (1) CA3078609A1 (https=)
EA (1) EA202090666A1 (https=)
WO (1) WO2019070478A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020176432A1 (en) * 2019-02-25 2020-09-03 Rush University Medical Center Compositions including cinnamic acid and methods of use thereof
AU2020315331A1 (en) 2019-07-16 2022-02-03 Rush University Medical Center Use of a benzoate containing composition to treat neurodegenerative disorders
CN116390761A (zh) 2020-10-28 2023-07-04 拉什大学医学中心 肉桂酸苄酯组合物在治疗甘氨酸脑病和尿素循环障碍中的应用
CA3205005A1 (en) * 2020-12-16 2022-06-23 Rush University Medical Center Administration of glycerol tribenzoate and glycerol phenylbutyrate for treatment of neurodegenerative and urea cycle disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2864161A1 (en) * 2012-02-10 2013-08-15 Whitehead Institute For Biomedical Research Inhibition of the glycine cleavage system for treatment of cancer
JP6836905B2 (ja) * 2014-01-17 2021-03-03 ラッシュ・ユニバーシティ・メディカル・センター 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用

Also Published As

Publication number Publication date
CN111212637A (zh) 2020-05-29
EA202090666A1 (ru) 2020-08-05
US20200281884A1 (en) 2020-09-10
EP3691630A4 (en) 2021-10-27
US11304923B2 (en) 2022-04-19
CA3078609A1 (en) 2019-04-11
AU2018345244A1 (en) 2020-04-02
BR112020005856A2 (pt) 2020-09-29
EP3691630A1 (en) 2020-08-12
AU2022200277A1 (en) 2022-02-03
JP2020536098A (ja) 2020-12-10
WO2019070478A1 (en) 2019-04-11

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