CA3078609A1 - The use of a benzoate containing composition to treat glycine encephalopathy - Google Patents
The use of a benzoate containing composition to treat glycine encephalopathy Download PDFInfo
- Publication number
- CA3078609A1 CA3078609A1 CA3078609A CA3078609A CA3078609A1 CA 3078609 A1 CA3078609 A1 CA 3078609A1 CA 3078609 A CA3078609 A CA 3078609A CA 3078609 A CA3078609 A CA 3078609A CA 3078609 A1 CA3078609 A1 CA 3078609A1
- Authority
- CA
- Canada
- Prior art keywords
- patient
- glyceryl
- formulation
- pharmaceutical composition
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762569251P | 2017-10-06 | 2017-10-06 | |
| US62/569,251 | 2017-10-06 | ||
| PCT/US2018/052879 WO2019070478A1 (en) | 2017-10-06 | 2018-09-26 | USE OF A BENZOATE-CONTAINING COMPOSITION FOR TREATING GLYCINIC ENCEPHALOPATHY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3078609A1 true CA3078609A1 (en) | 2019-04-11 |
Family
ID=65994915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3078609A Pending CA3078609A1 (en) | 2017-10-06 | 2018-09-26 | The use of a benzoate containing composition to treat glycine encephalopathy |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11304923B2 (https=) |
| EP (1) | EP3691630A4 (https=) |
| JP (1) | JP2020536098A (https=) |
| KR (1) | KR20200065012A (https=) |
| CN (1) | CN111212637A (https=) |
| AU (2) | AU2018345244A1 (https=) |
| BR (1) | BR112020005856A2 (https=) |
| CA (1) | CA3078609A1 (https=) |
| EA (1) | EA202090666A1 (https=) |
| WO (1) | WO2019070478A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020176432A1 (en) * | 2019-02-25 | 2020-09-03 | Rush University Medical Center | Compositions including cinnamic acid and methods of use thereof |
| AU2020315331A1 (en) | 2019-07-16 | 2022-02-03 | Rush University Medical Center | Use of a benzoate containing composition to treat neurodegenerative disorders |
| CN116390761A (zh) | 2020-10-28 | 2023-07-04 | 拉什大学医学中心 | 肉桂酸苄酯组合物在治疗甘氨酸脑病和尿素循环障碍中的应用 |
| CA3205005A1 (en) * | 2020-12-16 | 2022-06-23 | Rush University Medical Center | Administration of glycerol tribenzoate and glycerol phenylbutyrate for treatment of neurodegenerative and urea cycle disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2864161A1 (en) * | 2012-02-10 | 2013-08-15 | Whitehead Institute For Biomedical Research | Inhibition of the glycine cleavage system for treatment of cancer |
| JP6836905B2 (ja) * | 2014-01-17 | 2021-03-03 | ラッシュ・ユニバーシティ・メディカル・センター | 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用 |
-
2018
- 2018-09-26 EP EP18865150.9A patent/EP3691630A4/en active Pending
- 2018-09-26 KR KR1020207011606A patent/KR20200065012A/ko not_active Ceased
- 2018-09-26 EA EA202090666A patent/EA202090666A1/ru unknown
- 2018-09-26 WO PCT/US2018/052879 patent/WO2019070478A1/en not_active Ceased
- 2018-09-26 BR BR112020005856-4A patent/BR112020005856A2/pt not_active IP Right Cessation
- 2018-09-26 CN CN201880063022.9A patent/CN111212637A/zh active Pending
- 2018-09-26 JP JP2020519254A patent/JP2020536098A/ja active Pending
- 2018-09-26 AU AU2018345244A patent/AU2018345244A1/en not_active Abandoned
- 2018-09-26 CA CA3078609A patent/CA3078609A1/en active Pending
- 2018-09-26 US US16/648,422 patent/US11304923B2/en active Active
-
2022
- 2022-01-17 AU AU2022200277A patent/AU2022200277A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20200065012A (ko) | 2020-06-08 |
| CN111212637A (zh) | 2020-05-29 |
| EA202090666A1 (ru) | 2020-08-05 |
| US20200281884A1 (en) | 2020-09-10 |
| EP3691630A4 (en) | 2021-10-27 |
| US11304923B2 (en) | 2022-04-19 |
| AU2018345244A1 (en) | 2020-04-02 |
| BR112020005856A2 (pt) | 2020-09-29 |
| EP3691630A1 (en) | 2020-08-12 |
| AU2022200277A1 (en) | 2022-02-03 |
| JP2020536098A (ja) | 2020-12-10 |
| WO2019070478A1 (en) | 2019-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2022200277A1 (en) | The use of a benzoate containing composition to treat glycine encephalopathy | |
| US12478598B2 (en) | Compositions including cinnamic acid and methods of use thereof | |
| MXPA05002827A (es) | Formulaciones farmaceuticas de modafinil. | |
| EP3094616A1 (en) | The use of a benzoate containing composition in urea cycle disorders and neurodegenerativre disorders | |
| US20230255910A1 (en) | Use of a cinnamein composition for the treatment of glycine encephalopathy and urea cycle disorders | |
| US20240100008A1 (en) | Administration of glycerol tribenzoate and glycerol phenylbutyrate for treatment of neurodegenerative and urea cycle disorders | |
| US20240082184A1 (en) | Improved treatment for globoid cell leukodsytrophy or krabbe disease | |
| CA3104916C (en) | Pharmaceutical composition for preventing diabetes and use thereof | |
| US12514842B2 (en) | Use of a benzoate containing composition to treat neurodegenerative disorders | |
| HK40075156A (en) | Inhalation dosage forms of glycerol tribenzoate and/or glycerol dibenzoate for use in the treatment of huntington's disease | |
| HK40075156B (en) | Inhalation dosage forms of glycerol tribenzoate and/or glycerol dibenzoate for use in the treatment of huntington's disease | |
| CN107595863A (zh) | 一种用于降低血糖血脂的药物复方制剂及其用途 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20230921 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 6TH ANNIV.) - STANDARD Year of fee payment: 6 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20240920 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20240920 Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20240920 |
|
| D15 | Examination report completed |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT Effective date: 20241004 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20250203 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT Effective date: 20250220 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT Effective date: 20250523 |
|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20250523 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 7TH ANNIV.) - STANDARD Year of fee payment: 7 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250919 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250919 |
|
| D22 | Grant of ip right intended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D22-D128 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALLOWANCE REQUIREMENTS DETERMINED COMPLIANT Effective date: 20251220 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT Effective date: 20260127 |