KR20190083674A - 퀴놀린 화합물의 결정형 및 그의 제조 방법 - Google Patents

퀴놀린 화합물의 결정형 및 그의 제조 방법 Download PDF

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Publication number
KR20190083674A
KR20190083674A KR1020197019411A KR20197019411A KR20190083674A KR 20190083674 A KR20190083674 A KR 20190083674A KR 1020197019411 A KR1020197019411 A KR 1020197019411A KR 20197019411 A KR20197019411 A KR 20197019411A KR 20190083674 A KR20190083674 A KR 20190083674A
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South Korea
Prior art keywords
crystal
compound
crystal form
water
formula
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KR1020197019411A
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English (en)
Korean (ko)
Inventor
요시오 오하라
야스타카 다카다
히로오 마츠모토
아키히로 요시다
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닛산 가가쿠 가부시키가이샤
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34736450&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20190083674(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 닛산 가가쿠 가부시키가이샤 filed Critical 닛산 가가쿠 가부시키가이샤
Publication of KR20190083674A publication Critical patent/KR20190083674A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020197019411A 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법 Withdrawn KR20190083674A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2003-431788 2003-12-26
JP2003431788 2003-12-26
PCT/JP2004/019451 WO2005063711A1 (en) 2003-12-26 2004-12-17 Crystal form of quinoline compound and process for its production

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020187035028A Division KR20180132973A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020207003201A Division KR20200015826A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법

Publications (1)

Publication Number Publication Date
KR20190083674A true KR20190083674A (ko) 2019-07-12

Family

ID=34736450

Family Applications (11)

Application Number Title Priority Date Filing Date
KR1020197019411A Withdrawn KR20190083674A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020177001565A Withdrawn KR20170010111A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020167016139A Withdrawn KR20160075844A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020177023135A Withdrawn KR20170098976A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020207003201A Withdrawn KR20200015826A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020117002847A Ceased KR20110017936A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020187010082A Withdrawn KR20180040732A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020207032499A Ceased KR20200130510A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020067011877A Ceased KR20070001910A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020137001739A Withdrawn KR20130014643A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020187035028A Withdrawn KR20180132973A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법

Family Applications After (10)

Application Number Title Priority Date Filing Date
KR1020177001565A Withdrawn KR20170010111A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020167016139A Withdrawn KR20160075844A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020177023135A Withdrawn KR20170098976A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020207003201A Withdrawn KR20200015826A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020117002847A Ceased KR20110017936A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020187010082A Withdrawn KR20180040732A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020207032499A Ceased KR20200130510A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020067011877A Ceased KR20070001910A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020137001739A Withdrawn KR20130014643A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법
KR1020187035028A Withdrawn KR20180132973A (ko) 2003-12-26 2004-12-17 퀴놀린 화합물의 결정형 및 그의 제조 방법

Country Status (21)

Country Link
US (19) US20070112024A1 (enExample)
EP (1) EP1697326B1 (enExample)
JP (7) JP5186108B2 (enExample)
KR (11) KR20190083674A (enExample)
CN (2) CN1898211A (enExample)
AT (1) ATE518835T1 (enExample)
AU (2) AU2004309241A1 (enExample)
CA (1) CA2551050C (enExample)
CY (1) CY1112464T1 (enExample)
DK (1) DK1697326T3 (enExample)
ES (1) ES2367172T3 (enExample)
IL (1) IL176470A (enExample)
MX (1) MX338019B (enExample)
NZ (1) NZ548041A (enExample)
PL (1) PL1697326T3 (enExample)
PT (1) PT1697326E (enExample)
RU (1) RU2370489C2 (enExample)
SI (1) SI1697326T1 (enExample)
TW (1) TWI328006B (enExample)
WO (1) WO2005063711A1 (enExample)
ZA (1) ZA200605658B (enExample)

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WO2004072040A1 (en) 2003-02-12 2004-08-26 Ciba Specialty Chemicals Holding Inc. Crystalline forms of pitavastatin calcium
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
US7801272B2 (en) * 2007-09-28 2010-09-21 Rigaku Corporation X-ray diffraction apparatus and X-ray diffraction method
US20120022102A1 (en) * 2010-01-20 2012-01-26 Cadila Healthcare Limited Method for preparation of pitavastatin and its pharmaceutical acceptable salts thereof
KR101158517B1 (ko) 2010-04-29 2012-06-21 동방에프티엘(주) 고 순도 피타바스타틴 칼슘염 결정형 ａ의 제조방법
JP2013536219A (ja) * 2010-08-25 2013-09-19 カディラ・ヘルスケア・リミテッド ピタバスタチンカルシウムおよびその調製方法
WO2012063254A1 (en) 2010-11-12 2012-05-18 Hetero Research Foundation Novel polymorphs of pitavastatin calcium
RU2452939C1 (ru) * 2011-01-18 2012-06-10 Закрытое акционерное общество "Научные приборы" Рентгенодифракционный способ идентификации партий фармацевтической продукции
ITMI20111475A1 (it) * 2011-08-02 2013-02-03 Dipharma Francis Srl Forme cristalline di pitavastatina sale di calcio
WO2013037838A1 (en) 2011-09-12 2013-03-21 Farma Grs, D.O.O. Polymorphic form of pitavastatin calcium
WO2013098773A1 (en) * 2011-12-28 2013-07-04 Dr. Reddy's Laboratories Limited Crystalline forms of pitavastatin calcium
JP5190159B1 (ja) * 2012-08-08 2013-04-24 興和株式会社 医薬
CN104507949B (zh) * 2012-09-27 2017-07-28 日产化学工业株式会社 高纯度的含氮杂环化合物的制造方法
JP2014034574A (ja) * 2013-01-25 2014-02-24 Kowa Company Ltd 医薬
EP2970128B1 (en) * 2013-03-15 2019-12-04 Asieris Pharmaceutical Technologies Co., Ltd. Base addition salts of nitroxoline and uses thereof
CN105213319A (zh) * 2015-09-17 2016-01-06 青岛华之草医药科技有限公司 一种降血脂药物匹伐他汀钙组合物干混悬剂
JP2016222714A (ja) * 2016-09-20 2016-12-28 興和株式会社 医薬
TW202200547A (zh) * 2020-03-13 2022-01-01 印度商卡地拉保健有限公司 喹啉酮化合物的新穎鹽類
EP4308089A4 (en) * 2021-03-19 2025-02-26 Zydus Lifesciences Limited QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THEIR PREPARATION

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TWI328006B (en) 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production

Also Published As

Publication number Publication date
JP2016029102A (ja) 2016-03-03
US20210053923A1 (en) 2021-02-25
US20180072676A1 (en) 2018-03-15
KR20180132973A (ko) 2018-12-12
RU2006127044A (ru) 2008-02-10
KR20170098976A (ko) 2017-08-30
IL176470A0 (en) 2006-10-05
KR20110017936A (ko) 2011-02-22
AU2011213742C1 (en) 2017-04-06
CY1112464T1 (el) 2015-12-09
AU2011213742B2 (en) 2014-05-15
WO2005063711A1 (en) 2005-07-14
KR20180040732A (ko) 2018-04-20
JP2018052988A (ja) 2018-04-05
KR20130014643A (ko) 2013-02-07
NZ548041A (en) 2010-04-30
US20090176987A1 (en) 2009-07-09
KR20200015826A (ko) 2020-02-12
PT1697326E (pt) 2011-09-12
EP1697326A1 (en) 2006-09-06
HK1095328A1 (en) 2007-05-04
US20200216395A1 (en) 2020-07-09
US20130204000A1 (en) 2013-08-08
US20120245200A1 (en) 2012-09-27
ES2367172T3 (es) 2011-10-31
MX338019B (es) 2016-03-29
CN1898211A (zh) 2007-01-17
IL176470A (en) 2011-10-31
US20140058109A1 (en) 2014-02-27
JP2012072175A (ja) 2012-04-12
US20220177433A1 (en) 2022-06-09
CA2551050C (en) 2020-06-02
RU2370489C2 (ru) 2009-10-20
JP5186108B2 (ja) 2013-04-17
US20170226061A1 (en) 2017-08-10
US20190367458A1 (en) 2019-12-05
KR20170010111A (ko) 2017-01-25
US20110082298A1 (en) 2011-04-07
US20230322679A1 (en) 2023-10-12
ZA200605658B (en) 2007-11-28
JP2013136640A (ja) 2013-07-11
JP2017061536A (ja) 2017-03-30
ATE518835T1 (de) 2011-08-15
JP2014205719A (ja) 2014-10-30
TW200530186A (en) 2005-09-16
JP2007516952A (ja) 2007-06-28
KR20070001910A (ko) 2007-01-04
DK1697326T3 (da) 2011-09-19
US20190152916A1 (en) 2019-05-23
JP5267643B2 (ja) 2013-08-21
KR20160075844A (ko) 2016-06-29
CN102321019A (zh) 2012-01-18
US20110319624A1 (en) 2011-12-29
EP1697326B1 (en) 2011-08-03
KR20200130510A (ko) 2020-11-18
US20180297956A1 (en) 2018-10-18
SI1697326T1 (sl) 2011-11-30
CN102321019B (zh) 2016-06-08
US20140206719A1 (en) 2014-07-24
PL1697326T3 (pl) 2011-12-30
AU2011213742A1 (en) 2011-09-08
US20070112024A1 (en) 2007-05-17
TWI328006B (en) 2010-08-01
AU2004309241A1 (en) 2005-07-14
CA2551050A1 (en) 2005-07-14
US20150158816A1 (en) 2015-06-11
US20240294476A1 (en) 2024-09-05

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