KR20180065166A - Cosmetic composition for skin whitening containing pancratium maritimum extract and blue lotus extract - Google Patents

Abstract

The present invention relates to a skin-whitening cosmetic product. More specifically, the present invention relates to a skin-whitening cosmetic composition containing a sea daffodil (Pancratium maritimum) extract and a blue lotus (Nymphaea caerulea) extract. By containing both blue lotus and the sea daffodil extract exhibiting skin-whitening effects, the cosmetic composition whitens skin, and also alleviates skin irritation which is caused by sea daffodil in cosmetic products, thereby ensuring excellent formulation stability with little skin irritation.

Description

TECHNICAL FIELD [0001] The present invention relates to a cosmetic composition for skin whitening comprising an extract of sea daffodils and an extract of blue lotus as an active ingredient.

The present invention relates to a cosmetic composition, and more particularly, to a cosmetic composition for skin whitening comprising an extract of sea daffodils and an extract of blue lotus as an active ingredient.

It is the unequaled desire of all men to have white and fine skin. In general, the color of human skin, hair and eyes is determined by melanin, carotene and hemoglobin. In particular, melanin is the most important factor in determining skin color, and skin color is determined by the amount and nature of melanin and its degree of distribution. The pigment of human skin or hair protects skin and hair from the harmful effects of sunlight, especially ultraviolet rays. For example, people who lack these pigments are very susceptible to sunlight and are susceptible to burns, and the likelihood of developing skin cancer at a young age is high. Short wavelength ultraviolet (290-320 nm) and carcinogens are known to form harmful radicals, such as oxygen radicals, in the skin, and these oxygen radicals attack skin cells and aging skin.

In general, the darkening of the human skin is caused by the melanin pigment produced in the skin. Although it does not cause excessive production of melanin in the normal state, the skin is affected by external stimuli such as ultraviolet rays, environmental pollution, stress, hormones, , It causes hyperproduction of melanin pigment, which is not released out of the skin but remains in the skin, resulting in pigmentation.

The main function of melanin is to remove these harmful radicals to protect the skin from damage caused by it. Thus, a high amount of melanin means that it has an effective countermeasure to protect the skin from physical or chemical toxicants

On the other hand, in melanocytes in the human body, enzymes such as tyrosinase, TRP (tyrosinase related protein) -1 and TRP-2 exist, and tyrosine (L-tyrosine) (Cohen, T., et al. Nucleic Acids Res., 18: 2807-2808 (1990)); (Jackson, I. J., et al., EMBO J., 11: 327-535 (1992)). This enzymatic reaction takes place in the melanosome, the organelle within the pigmented cells, and melanosomes containing the newly produced melanin are distributed to adjacent keratinocytes through the dendrites of the pigmented cells, Make skin color appear.

Melanin absorbs the light energy of sunlight UV and protects the subcutaneous skin organs from UV damage. It also helps protect the skin from external harmful factors such as harmful oxygen and free radicals generated in the skin. It plays a role. However, abnormal production of melanin causes skin lesions such as vitiligo. On the other hand, when melanin is not completely eliminated due to over-synthesis or keratinization of melanin due to sunlight, hormonal changes, inflammation or medicines, In addition to streaking, pigmentation of the skin is deposited, forming spots and freckles, and it also causes skin cancer from such lesions. Therefore, in order to prevent such pigmentation phenomenon, it is necessary to inhibit a part of the melanin production process to reduce the production of melanin.

Free radicals occur in normal or pathological cell metabolism by external factors such as foreign substances or UV irradiation. When the human body is used the oxygen to the breathing and combustion, molecular and oxygen free radicals and reacts readily superoxide (· O ₂ ^-), hydrogen peroxide (H ₂ O _2), hydroxyl radical (· OH), peroxy radical (ROO ^- ) and other reactive oxygen species (ROS). These ROSs act as excellent oxidizing and nitrifying agents, damaging major constituents in the body such as lipids, proteins, nucleic acids and DNA, causing physiological disorders and, in severe cases, causing disease and loss of life. It is also known that reactive oxygen species attack the unsaturated fatty acid which is a constituent of cell membrane and cause peroxidation reaction, and thus, lipid peroxidation accumulated in vivo causes aging and various lesions.

In the field of conventional cosmetics, inhibitors that inhibit tyrosinase activity such as kojic acid, arbutin, hydroquinone, vitamin C and derivatives thereof, licorice extract, etc. have been used as whitening ingredients . However, they have problems in stability within the formulation and their use is limited.

Korean Patent No. 10-0920896 discloses a cosmetic composition for skin whitening which simultaneously contains blue lotus and tetrahydrocurcumin.

Accordingly, the present inventors have made intensive efforts to overcome the problems of conventional skin whitening cosmetic compositions such as stability, side effects, and whitening effect of cosmetics. As a result, it has been found that the sea daffodil extract has excellent effect of inhibiting the activity of tyrosinase, And that the skin whitening effect was enhanced when used together with blue lotus, thereby completing the present invention.

The present invention relates to a skin whitening cosmetic composition containing an extract of sea daffodils and a blue lotus extract.

Preferably, the cosmetic composition has a decomposing effect on tyrosinase.

Preferably, the mixing weight ratio of the sea aniline extract to the blue lotus extract is from 4: 1 to 2: 5.

The present invention provides a cosmetic composition for skin whitening comprising an extract of sea daffodils and a blue lotus extract as an active ingredient. By using the sea daffodil extract and blue lotus extract of the present invention for the skin, the whitening effect increases synergistically, and the conventional skin cosmetic skin irritation is also reduced, so that it can be usefully used as a cosmetic composition for skin whitening.

As a result of research on various plant extracts to search for a substance having a skin whitening effect, the inventors found that an extract obtained from sea daffodil has a skin whitening effect and a whitening effect due to a synergy effect when it is used together with a blue lotus. .

Pancratium Maritimum , also known as Sea daffodil, is a type of bulbous plant that grows in the Black Sea and Mediterranean coasts of Portugal, Turkey, Israel and Syria. Sea daffodils are common on the beach and in the sand on the coast.

The sea daffodil extract of the present invention refers to an extract obtained from a variety of organs such as outposts, leaves, stems, roots, flowers and seeds of sea daffodils by a conventional method, and preferably refers to an extract obtained from leaves or flowers.

Blue lotus, blue lotus, Nymphaea caerulea ) is a perennial plant belonging to the water lily family. It is native to South Africa and is a wild herb with a leaf of about 30 cm in diameter. It grows much in the islands near South Asia and East Asia. Called the blue lotus, blue lotus, blue rhinoceros, etc., the name of the plant is due to the blossoming of blue flowers. It is said to contain antioxidants and antioxidants and to inhibit free radicals.

The blue lotus extract of the present invention is obtained by extracting from a variety of organs such as water lily and leaves, stems, roots, flowers and seeds of plants by an ordinary method, and preferably refers to an extract obtained from leaves or flowers.

The sea daffodil extract and blue lotus extract of the present invention can be prepared using conventional solvents according to conventional methods known in the art, that is, under the conditions of ordinary temperature and pressure, preferably (a) Water, anhydrous or hydrous lower alcohols having 1 to 4 carbon atoms (e.g., methanol, ethanol, propanol and butanol), propylene glycol, 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, (B) solvent extraction using a solvent selected from the group consisting of dichloromethane, chloroform, hexane and mixtures thereof, (b) supercritical extraction with carbon dioxide and supercritical extraction with high temperature, or (c) ultrasonic extraction.

In the present invention, a solvent extraction method using an extraction solvent is preferably used. In the present invention, the sea daffodil extract and the blue lotus extract can be used in various extraction solvents, for example, water, anhydrous or lower alcohols having 1 to 4 carbon atoms (e.g., methanol, ethanol, propanol and butanol), propylene glycol, Can be obtained by using at least one extraction solvent selected from the group consisting of 3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform, hexane and mixtures thereof, Is obtained by using ethanol, 70% (v / v) ethanol or water, and most preferably by using 70% (v / v) ethanol.

It is apparent to those skilled in the art that the extract of sea daffodils and blue lotus extract of the present invention can obtain an extract having substantially the same effect not only by the above-mentioned extraction solvent but also by other extraction solvent. In addition, the sea daffodil extract and blue lotus extract of the present invention include extracts obtained by the conventional extraction and fermentation as well as the extracts obtained by the above-mentioned extraction solvent. For example, decompression by carbon dioxide, extraction by supercritical extraction with high temperature, extraction by extraction using ultrasound, separation by ultrafiltration membrane with constant molecular weight cutoff value, various chromatography (size, charge, hydrophobic or affinity And the active fraction obtained through various purification and extraction methods, such as those extracted by fermentation products using natural or various microorganisms, are also included in the extract of the present invention. Further, the present invention provides a cosmetic composition characterized in that the above extract is obtained by liquid-freezing obtained by cold-pressing and heating filtration at room temperature, and further by concentrating or lyophilizing the solvent under reduced pressure.

The supercritical fluid extraction refers to supercritical fluid extraction. Generally, the supercritical fluid is extracted from the liquid and the gas when the gas reaches the critical point at high temperature and high pressure. Gas properties and has chemically similar polarity to nonpolar solvents. Due to these properties, supercritical fluids have been used to extract lipophilic substances (J. Chromatogr. A. 1998; 479: 200-205). Carbon dioxide is a supercritical fluid with both liquid and gaseous nature, with the operation of supercritical fluid equipment reaching its critical pressure and temperature, resulting in increased solubility in fat-soluble solutes. When supercritical carbon dioxide passes through an extraction vessel containing a certain amount of sample, the lipophilic substance contained in the sample is extracted into supercritical carbon dioxide. When the supernatant carbon dioxide containing a small amount of cosolvent is passed through the sample remaining in the extraction vessel after extracting the lipid-soluble substance, components that were not extracted by pure supercritical carbon dioxide can be extracted.

The supercritical fluid used in the supercritical extraction method of the present invention can effectively extract an active ingredient by using a mixed fluid in which a cosolvent is further mixed with supercritical carbon dioxide or carbon dioxide. These co-solvents may be used alone or in admixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, hexane and diethyl ether. Most of the extracted samples contain carbon dioxide. Since the carbon dioxide is volatilized into air at room temperature, the extract obtained by the above method can be used as a cosmetic composition, and the cosolvent can be removed by a reduced pressure evaporator.

In addition, the ultrasonic extraction method is an extraction method using energy generated by ultrasonic vibration. Ultrasonic waves can destroy an insoluble solvent contained in a sample in a water-soluble solvent. Due to the high local temperature, Since the kinetic energy of the reactant particles is increased, sufficient energy required for the reaction is obtained. By inducing the high pressure by the shock effect of the ultrasonic energy, the mixing effect of the substance contained in the sample and the solvent is enhanced, thereby increasing the extraction efficiency. As the extraction solvent which can be used for the ultrasonic extraction method, one or a mixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, hexane and diethyl ether can be used. The extracted sample is recovered by vacuum filtration, and the filtrate is recovered, and the extract is removed by a vacuum evaporator and freeze-dried to obtain an extract.

The sea daffodil extract and blue lotus extract according to the present invention also include fermented extracts. The fermented extract of sea daffodil and the blue lotus fermented extract can be prepared as follows. After finely crushing the sample to a size of about 100 to 500 mesh, 1 to 50 g / L of a conventional microorganism culture solution is added, and microorganisms such as yeast or lactic acid bacteria are added in an amount of 10,000 to 100,000 cfu / L. The culture temperature is 30 to 37 ° C. The pH is 5 to 7 and aerobic or anaerobic conditions are maintained for about 5 to 10 days. Which can be obtained through aging and filtration.

According to the present invention, the sea dandelion extract is contained in an amount of 0.0001 to 50.0% by weight based on the total weight of the cosmetic composition, more preferably, the sea dandelion extract is contained in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic composition . When the content of the extract is less than 0.0001% by weight, the effect of improving the skin is not exhibited. When the content of the extract is more than 50.0% by weight, the degree of improvement of the skin against the increase of the content is insignificant, It is not even.

According to the present invention, the blue lotus extract is contained in an amount of 0.0001 to 50.0% by weight based on the total weight of the cosmetic composition relative to the total weight of the cosmetic composition, and more preferably, 10% by weight. When the content of the extract is less than 0.0001% by weight, the effect of improving the skin is not exhibited. When the content of the extract is more than 50.0% by weight, the degree of improvement of the skin against the increase of the content is insignificant, It is not even.

The blend weight ratio of the sea daffodil extract to the blue lotus extract may be 4: 1 to 2: 5, but is not limited thereto. When the blend weight ratio of the sea daffodil extract and the blue lotus extract is out of the above range, the synergistic effect obtained by mixing the respective extracts is relatively low.

The ingredients contained in the cosmetic composition of the present invention may contain, as an active ingredient, the ingredients commonly used in cosmetic compositions in addition to the above-mentioned effective ingredients, and may contain conventional ingredients such as antioxidants, stabilizers, solubilizers, vitamins, Supplements, and carriers.

The cosmetic composition of the present invention can be prepared into any of the formulations conventionally produced in the art and can be used in the form of solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, , Oil, powdered foundation, emulsion foundation, wax foundation, pack, massage cream and spray, but is not limited thereto. More specifically, it can be manufactured in the form of a soft lotion, a nutritional lotion, a nutritional cream, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray or a powder.

When the formulation of the present invention is a paste, cream or gel, an animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component .

When the formulation of the present invention is a solution or an emulsion, a solvent, a dissolving agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters.

In the case where the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used. When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, / Propane or dimethyl ether.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide ether Alkylamido betaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.

When the cosmetic composition of the present invention is a soap, a surfactant-containing cleansing formulation or a surfactant-free cleansing formulation, it may be applied to the skin and then wiped off, washed or rinsed with water. The surfactant-containing cleansing formulation may be a cleansing foam, a cleansing water, a cleansing towel and a cleansing pack. The surfactant-free cleansing formulation may be a cleansing cream, , Cleansing lotion, cleansing water and cleansing gel, but is not limited thereto.

On the other hand, the cosmetic process of the present invention refers to all cosmetic processes using the cosmetic composition of the present invention. That is, all methods known in the art using a cosmetic composition belong to the cosmetic method of the present invention. The cosmetic composition of the present invention may be used alone or in combination, or may be used in combination with other cosmetic compositions other than the present invention. The cosmetic composition according to the present invention may be used according to a conventional method of use, and may be used in a number of times depending on the skin condition or taste of the user.

By using the sea daffodil extract and blue lotus extract of the present invention for the skin, the whitening effect increases synergistically, and the conventional skin cosmetic skin irritation is also reduced, so that it can be usefully used as a cosmetic composition for skin whitening.

These embodiments are only for describing the present invention in more detail, and the scope of the present invention is not limited by these embodiments in accordance with the gist of the present invention.

[ Manufacturing example  One] Sea daffodils  Extract preparation

The shamed sea daffodil was refluxed three times for 5 hours with 70% (v / v) ethanol aqueous solution, cold-frozen, and filtered through Whatman # 4 filter paper. The filtered extract was concentrated under reduced pressure and freeze-dried at 50 DEG C or lower.

[ Manufacturing example  2] Blue Lotus  Extract preparation

The shaded blue lotus was refluxed three times for 5 hours with 70% (v / v) aqueous ethanol solution, cooled down, and filtered through Whatman # 4 filter paper. The filtered extract was concentrated under reduced pressure and freeze-dried at 50 DEG C or lower.

[ Test Example  One] Sea Daffodil Extract and Blue Lotus  Extract Tyrosinase  Active inhibition measure

Tyrosinase was isolated and purified from mushroom and purchased from Sigma (USA). As a substrate, L-tyrosine (Sigma) was dissolved in 0.05 M sodium phosphate buffer solution (pH 6.8) to prepare a 0.1 mg / ml solution. The test substance was dissolved in a 0.05 M sodium phosphate buffer solution (pH 6.8) adjusted to an appropriate concentration and then used. The sea daffodil extract was used in Preparation Example 1, and the blue lotus extract was used in Preparation Example 2. 0.5 ml of L-tyrosine solution was placed in a test tube, 0.5 ml of the sample solution was added thereto, and the mixture was allowed to stand at 37 DEG C for 10 minutes. Then, 0.5 ml of 200 units / ml tyrosinase was added to each sample solution, and the mixture was reacted at 37 ° C for 10 minutes. The reaction tube was placed on ice to quench the reaction, and the absorbance at 475 nm was measured with a spectrophotometer. As a control group, 0.5 ml of a buffer solution was used instead of the sample solution.

The inhibition rate of tyrosinase activity of each sample liquid was calculated according to the following equation (1), and the experimental results are shown in Tables 1 to 3 below.

Sea Daffodil Extract (㎍ / mL) Inhibition rate of enzyme activity (%) 5 3.5 10 10.2 20 16.4 50 30.9 100 41.1 200 67.8

Blue Lotus extract (/ / mL) Inhibition rate of enzyme activity (%) 5 3.2 10 5.7 20 8.4 50 12.3 100 19.6 200 20.9

Sea Daffodil Extract (㎍ / mL) Blue Lotus Extract (/ / mL) Inhibition rate of enzyme activity (%) 20 0 16.4 20 5 27.6 20 10 34.8 20 20 51.9

As can be seen from Tables 1 and 2, it was confirmed that the effect of inhibiting the tyrosinase activity and the enzyme activity of blue lotus was relatively low. However, as shown in Table 3, it can be seen that when the sea daffodil extract and the blue lotus extract were used simultaneously, the inhibition rate of the enzyme activity was significantly increased as compared with the case of using each.

[ Example  And Comparative example  Produce]

In order to confirm the whitening effect of the sea daffodil extract and the blue lotus extract, a whitening lotion was prepared according to the composition shown in Table 4 below.

(Unit: wt%) ingredient Comparative Example
One Comparative Example
2 Comparative Example
3 Comparative Example
4 Comparative Example
5 Comparative Example
6 Comparative Example
7 Comparative Example
8 Comparative Example
9 Example
One Example
2 Example
3 Example
4 Sea daffodils
The extract (Preparation Example 1) - 0.5 1.0 2.0 5.0 - - - - 2.0 2.0 2.0 2.0 Blue Lotus
The extract (Preparation Example 2) 0.5 1.0 2.0 5.0 0.5 1.0 2.0 5.0 EDTA-2Na 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 Cetostearyl alcohol 2 2 2 2 2 2 2 2 2 2 2 2 2 Glyceryl stearate 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 Microcrystalline 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 Squalane 5 5 5 5 5 5 5 5 5 5 5 5 5 Liquid paraffin 3 3 3 3 3 3 3 3 3 3 3 3 3 Trioctanoin 5 5 5 5 5 5 5 5 5 5 5 5 5 Polysorbate 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 Sorbitan stearate 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Tocopheryl acetate 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 Cyclomethicone 3 3 3 3 3 3 3 3 3 3 3 3 3 BHT 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Incense, preservative Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount

[ Test Example  2] Sea daffodils  The extract and Blue Lotus  Measurement of whitening effect of extract

The whitening effect of each of the cosmetics of Comparative Examples 1 to 9 and Examples 1 to 4 was measured for 39 women aged 26 to 45 years whose skin color was dark. Ten sections of the subject's arms were displayed in 1 cm square, each cosmetic material was applied, and the remaining one was used as a control group. The cosmetic was applied twice a day for 2 months. The skin color (L value) was measured after a lapse of 2 months using a measuring device, Minolta CR 300, and the degree of change in skin color was calculated using the following equation (2).

division Comparative Example
One Comparative Example
2 Comparative Example
3 Comparative Example
4 Comparative Example
5 Comparative Example
6 Comparative Example
7 Comparative Example
8 Comparative Example
9 Example
One Example
2 Example
3 Example
4 DELTA L value 0.53 2.98 3.03 3.13 3.22 0.93 1.01 1.03 1.01 3.66 3.71 3.78 3.85

As can be seen from the results of Table 5, in which the skin effect of each composition of Comparative Examples 1 to 9 and Examples 1 to 4 was measured, when compared with Comparative Example 1 in which no extract was contained, , The ΔL value was increased in proportion to the addition of the concentration, and in particular, when used together with the blue lotus, the ΔL value was increased compared with the case of using alone, thereby confirming that the whitening enhancing effect was obtained.

[ Test Example  3] Sea daffodil extract Blue Lotus  Skin irritation test of extract

To test the skin irritation of each of the cosmetics of the comparative examples and the examples prepared above, a patch test was conducted on 20 healthy male and female adults using a Hayes test chamber. The test site was wiped with 70% ethanol and dried. Then, a chamber (Finn chamber, 100 × 10, EPITEST, Finland) in which 15 μg of the prepared test substance was dropped was hermetically sealed to the inside of the forearm of the test subject. After 24 hours of exposure, the patches were removed and marked with the marking pen. (8MC-150, DAZOR, United States of America) at 1 hour and 24 hours (24 hours, 48 hours, including 1 hour and 24 hours after removal of the patches) Respectively. The skin response was determined according to the provisions of the International Contact Dermatitis Research Group (ICDRG) (Table 6), and the average skin response was calculated according to the following equation (3), and the results are shown in Table 7 below.

sign score Evaluation standard - 0.0 Non-reactive, normal skin ± 0.5 Faint or mild erythema + 1.0 The border is clear but weak erythema, ++ 2.0 Clear erythema, papules and small follicles +++ 3.0 Severe erythema and vesicle formation ++++ 6.0 Algebraic formation

Test substance 24 hours 48 hours Mean skin response (n = 20) ? + ++ ? + ++ Comparative Example 1 1 1 - One - - 0.48 Comparative Example 2 - - - - - - 0.17 Comparative Example 3 - - - - - - 0.18 Comparative Example 4 - - - - - - 0.15 Comparative Example 5 - - - - - - 0.18 Comparative Example 6 - - - - - - 0.17 Comparative Example 7 - - - - - - 0.16 Comparative Example 8 - - - - - - 0.17 Comparative Example 9 - - - - - - 0.16 Example 1 - - - - - - 0.17 Example 2 - - - - - - 0.16 Example 3 - - - - - - 0.17 Example 4 - - - - - - 0.16

From the results of Table 7, it was confirmed that the use of the example containing the sea daffodil extract and the blue lotus extract showed a superior stimulation relaxation effect as compared with the comparative example.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the same is by way of illustration and example only and is not to be construed as limiting the scope of the present invention. It is therefore intended that the scope of the invention be defined by the claims appended hereto and their equivalents.

Claims (3)

A cosmetic composition for skin whitening comprising an extract of sea daffodils and a blue lotus extract. The cosmetic composition according to claim 1, wherein the cosmetic composition has a decomposing effect of tyrosinase. The cosmetic composition according to claim 1, wherein the mixing ratio of the sea aniline extract and the blue lotus extract is 4: 1 to 2: 5.