KR20180027576A - 면역 체크포인트 억제제를 사용하여 암을 치료하는 방법 - Google Patents

면역 체크포인트 억제제를 사용하여 암을 치료하는 방법 Download PDF

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KR20180027576A
KR20180027576A KR1020187003984A KR20187003984A KR20180027576A KR 20180027576 A KR20180027576 A KR 20180027576A KR 1020187003984 A KR1020187003984 A KR 1020187003984A KR 20187003984 A KR20187003984 A KR 20187003984A KR 20180027576 A KR20180027576 A KR 20180027576A
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antibody
antigen
hpv
binding portion
tumor
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Korean (ko)
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데메트리오스 마네카스
조셉 그로쏘
제프리 안데르손
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브리스톨-마이어스 스큅 컴퍼니
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56551000&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20180027576(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 브리스톨-마이어스 스큅 컴퍼니 filed Critical 브리스톨-마이어스 스큅 컴퍼니
Priority to KR1020257014642A priority Critical patent/KR20250065936A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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KR1020187003984A 2015-07-14 2016-07-14 면역 체크포인트 억제제를 사용하여 암을 치료하는 방법 Ceased KR20180027576A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257014642A KR20250065936A (ko) 2015-07-14 2016-07-14 면역 체크포인트 억제제를 사용하여 암을 치료하는 방법

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562192396P 2015-07-14 2015-07-14
US62/192,396 2015-07-14
PCT/US2016/042297 WO2017011666A1 (en) 2015-07-14 2016-07-14 Method of treating cancer using immune checkpoint inhibitor

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KR1020257014642A Division KR20250065936A (ko) 2015-07-14 2016-07-14 면역 체크포인트 억제제를 사용하여 암을 치료하는 방법

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KR20180027576A true KR20180027576A (ko) 2018-03-14

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KR1020187003984A Ceased KR20180027576A (ko) 2015-07-14 2016-07-14 면역 체크포인트 억제제를 사용하여 암을 치료하는 방법
KR1020257014642A Pending KR20250065936A (ko) 2015-07-14 2016-07-14 면역 체크포인트 억제제를 사용하여 암을 치료하는 방법

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US (3) US10544224B2 (cg-RX-API-DMAC7.html)
EP (2) EP3858859B1 (cg-RX-API-DMAC7.html)
JP (3) JP2018522887A (cg-RX-API-DMAC7.html)
KR (2) KR20180027576A (cg-RX-API-DMAC7.html)
CN (1) CN107922502A (cg-RX-API-DMAC7.html)
CY (1) CY1123993T1 (cg-RX-API-DMAC7.html)
DK (2) DK3322731T3 (cg-RX-API-DMAC7.html)
ES (1) ES2855798T3 (cg-RX-API-DMAC7.html)
FI (1) FI3858859T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20210399T1 (cg-RX-API-DMAC7.html)
HU (1) HUE053966T2 (cg-RX-API-DMAC7.html)
LT (1) LT3322731T (cg-RX-API-DMAC7.html)
PL (1) PL3322731T3 (cg-RX-API-DMAC7.html)
PT (1) PT3322731T (cg-RX-API-DMAC7.html)
RS (1) RS61532B1 (cg-RX-API-DMAC7.html)
SI (1) SI3322731T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202100131T1 (cg-RX-API-DMAC7.html)
WO (1) WO2017011666A1 (cg-RX-API-DMAC7.html)

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WO2021118321A1 (ko) * 2019-12-13 2021-06-17 삼성바이오에피스 주식회사 안정한 항-pd-1 항체 약제학적 제제
KR20210100539A (ko) 2020-02-06 2021-08-17 영남대학교 산학협력단 면역 체크포인트 억제제 및 ampk 활성화제를 유효성분으로 함유하는 암질환 예방 또는 치료용 조성물
KR20240013352A (ko) 2022-07-22 2024-01-30 가톨릭대학교 산학협력단 디옥시시코닌 또는 그의 약제학적으로 허용가능한 염을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물
KR20240101085A (ko) * 2022-12-23 2024-07-02 가톨릭대학교 산학협력단 켈레리트린 클로라이드 또는 그의 약제학적으로 허용가능한 염을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물

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WO2017157882A1 (en) 2016-03-14 2017-09-21 Université Catholique de Louvain Serine biosynthetic pathway inhibitors
EP3484478B1 (en) * 2016-07-15 2025-11-05 Viracta Subsidiary, Inc. Histone deacetylase inhibitors for use in immunotherapy
US11274154B2 (en) * 2016-10-06 2022-03-15 Pfizer Inc. Dosing regimen of avelumab for the treatment of cancer
EP3551225A1 (en) 2016-12-07 2019-10-16 Agenus Inc. Antibodies and methods of use thereof
MD3551660T2 (ro) 2016-12-07 2024-03-31 Agenus Inc Anticorpi anti-CTLA-4 și procedee de utilizare a acestora
US11168144B2 (en) 2017-06-01 2021-11-09 Cytomx Therapeutics, Inc. Activatable anti-PDL1 antibodies, and methods of use thereof
WO2018226529A1 (en) * 2017-06-05 2018-12-13 The Regents Of The University Of Michigan Complexes for delivery of antigenic peptides
TW201932839A (zh) * 2018-01-12 2019-08-16 美商格瑞爾公司 用於分析病毒核酸之方法
MA51844A (fr) * 2018-02-13 2021-05-19 Merck Sharp & Dohme Méthodes de traitement du cancer avec des anticorps anti pd-1 et des anticorps anti ctla4
WO2019175328A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4pathwayactivationandusethereoffortreatingcancer
EP3774911A1 (en) * 2018-03-30 2021-02-17 Bristol-Myers Squibb Company Methods of treating tumor
EP3801501A4 (en) 2018-06-06 2022-03-23 The Regents of the University of California ESTROGEN RECEPTOR INHIBITORS AND THEIR USES
US20210255168A1 (en) * 2018-06-13 2021-08-19 King Faisal Specialist Hospital & Research Centre A method of precision cancer therapy
CN114340679A (zh) * 2018-10-31 2022-04-12 基因泰克公司 用于治疗对pd-1/pd-l1信号传导抑制剂无应答的癌症的方法和药物
WO2020156500A1 (zh) * 2019-01-31 2020-08-06 正大天晴药业集团股份有限公司 抗pd-l1抗体治疗头颈癌的用途
CA3162311A1 (en) * 2019-12-20 2021-06-24 Philip E. Brandish Methods for treating cancer using a combination of a pd-1 antagonist, an ilt4 antagonist, and chemotherapeutic agents

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KR20240101085A (ko) * 2022-12-23 2024-07-02 가톨릭대학교 산학협력단 켈레리트린 클로라이드 또는 그의 약제학적으로 허용가능한 염을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물

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