KR20170047265A - 25-하이드록시비타민 d를 이용한 보조요법 - Google Patents

25-하이드록시비타민 d를 이용한 보조요법 Download PDF

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KR20170047265A
KR20170047265A KR1020177006349A KR20177006349A KR20170047265A KR 20170047265 A KR20170047265 A KR 20170047265A KR 1020177006349 A KR1020177006349 A KR 1020177006349A KR 20177006349 A KR20177006349 A KR 20177006349A KR 20170047265 A KR20170047265 A KR 20170047265A
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South Korea
Prior art keywords
hydroxyvitamin
patient
effective amount
hypocalcemia
bone
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Korean (ko)
Inventor
피. 마틴 펫코비치
조엘 지. 멜닉
제이 에이. 화이트
사미르 피. 타바쉬
찰스 더블유. 비숍
수잔 에이취. 피얼스
스테픈 에이. 스트러그넬
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옵코 아일랜드 글로벌 홀딩스 리미티드
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Application filed by 옵코 아일랜드 글로벌 홀딩스 리미티드 filed Critical 옵코 아일랜드 글로벌 홀딩스 리미티드
Publication of KR20170047265A publication Critical patent/KR20170047265A/ko
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
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    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
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    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
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  • Inorganic Chemistry (AREA)
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  • Molecular Biology (AREA)
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  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020177006349A 2014-08-07 2015-08-06 25-하이드록시비타민 d를 이용한 보조요법 Ceased KR20170047265A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462034604P 2014-08-07 2014-08-07
US62/034,604 2014-08-07
PCT/EP2015/068219 WO2016020508A2 (en) 2014-08-07 2015-08-06 Adjunctive therapy with 25-hydroxyvitamin d

Publications (1)

Publication Number Publication Date
KR20170047265A true KR20170047265A (ko) 2017-05-04

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Application Number Title Priority Date Filing Date
KR1020177006349A Ceased KR20170047265A (ko) 2014-08-07 2015-08-06 25-하이드록시비타민 d를 이용한 보조요법
KR1020187011558A Active KR102677359B1 (ko) 2014-08-07 2016-02-10 25-하이드록시비타민 d를 이용한 보조요법 및 그 용품

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KR1020187011558A Active KR102677359B1 (ko) 2014-08-07 2016-02-10 25-하이드록시비타민 d를 이용한 보조요법 및 그 용품

Country Status (21)

Country Link
US (2) US20180085381A1 (enExample)
EP (1) EP3193925A2 (enExample)
JP (5) JP2017523220A (enExample)
KR (2) KR20170047265A (enExample)
CN (2) CN114681468A (enExample)
AU (2) AU2015298858A1 (enExample)
BR (1) BR112017002526A2 (enExample)
CA (1) CA2957240A1 (enExample)
CL (1) CL2017000317A1 (enExample)
CO (2) CO2018004206A2 (enExample)
CR (2) CR20170085A (enExample)
EA (1) EA201790332A1 (enExample)
EC (1) ECSP17014159A (enExample)
IL (1) IL250462A0 (enExample)
MX (1) MX2017001751A (enExample)
MY (1) MY203284A (enExample)
PE (1) PE20170392A1 (enExample)
PH (2) PH12017500228A1 (enExample)
SG (2) SG11201700858RA (enExample)
TW (2) TWI778934B (enExample)
WO (1) WO2016020508A2 (enExample)

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PL2679228T3 (pl) 2006-06-21 2018-07-31 Opko Ireland Global Holdings, Ltd. Terapia z użyciem środka do uzupełniania witaminy D i środka do zastępowania hormonami witaminy D
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 d 부족 및 결핍의 치료 방법
SI2481400T1 (sl) 2007-04-25 2014-11-28 Opko IP Holdings II, Inc. Nadzorovano oralno sproščanje sestavkov, ki vsebujejo spojino vitamina D in voskasti nosilec
EP3636280B1 (en) 2010-03-29 2025-05-14 EirGen Pharma Ltd. Methods and compositions for reducing parathyroid levels
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US10220047B2 (en) * 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
SG10201913863TA (en) 2016-03-28 2020-03-30 Opko Ireland Global Holdings Limited Methods of vitamin d treatment
PT3246032T (pt) * 2016-05-20 2021-10-18 Christoph Karl Composições farmacêuticas com ácido zoledrónico, cálcio e vitamina d adequadas para tratamento e/ou profilaxia de doenças do metabolismo ósseo e de efeitos secundários relacionados com terapia, como hipocalcemias
US20190290756A1 (en) * 2016-05-20 2019-09-26 Christoph Karl Pharmaceutical compositions with anti-rankl antibodies, calcium and vitamin d
CN108519448B (zh) * 2018-04-04 2021-04-13 北京市心肺血管疾病研究所 25-羟基维生素d在制备大动脉炎患者疾病活动性评判试剂盒中的应用
MY210476A (en) 2018-08-31 2025-09-24 Opko Ireland Global Holdings Ltd Vitamin d pediatric dosage forms, methods of making and using
CA3176559A1 (en) * 2020-04-06 2021-10-14 Eirgen Pharma Ltd. 25-hydroxyvitamin d for the treatment of sars-cov-2 infection
WO2025094144A1 (en) 2023-11-02 2025-05-08 Eirgen Pharma Ltd. Controlling loss of kidney function

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