CN114681468A - 利用25-羟基维生素d的辅助疗法 - Google Patents

利用25-羟基维生素d的辅助疗法 Download PDF

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Publication number
CN114681468A
CN114681468A CN202210347507.9A CN202210347507A CN114681468A CN 114681468 A CN114681468 A CN 114681468A CN 202210347507 A CN202210347507 A CN 202210347507A CN 114681468 A CN114681468 A CN 114681468A
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Prior art keywords
hydroxyvitamin
patient
cancer
agent
hypocalcemia
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Pending
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CN202210347507.9A
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Chinese (zh)
Inventor
马丁·P·佩特科维奇
乔尔·Z·梅尔尼克
杰伊·A·怀特
萨米尔·P·塔巴什
查理斯·W·比绍夫
苏珊·H·皮尔斯
斯蒂芬·A·斯特拉格内尔
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Opko Ireland Global Holdings Ltd
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Opko Ireland Global Holdings Ltd
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Application filed by Opko Ireland Global Holdings Ltd filed Critical Opko Ireland Global Holdings Ltd
Publication of CN114681468A publication Critical patent/CN114681468A/zh
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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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CN202210347507.9A 2014-08-07 2015-08-06 利用25-羟基维生素d的辅助疗法 Pending CN114681468A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462034604P 2014-08-07 2014-08-07
US62/034,604 2014-08-07
CN201580047452.8A CN106604733A (zh) 2014-08-07 2015-08-06 利用25‑羟基维生素d的辅助疗法
PCT/EP2015/068219 WO2016020508A2 (en) 2014-08-07 2015-08-06 Adjunctive therapy with 25-hydroxyvitamin d

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580047452.8A Division CN106604733A (zh) 2014-08-07 2015-08-06 利用25‑羟基维生素d的辅助疗法

Publications (1)

Publication Number Publication Date
CN114681468A true CN114681468A (zh) 2022-07-01

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ID=53783233

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Application Number Title Priority Date Filing Date
CN202210347507.9A Pending CN114681468A (zh) 2014-08-07 2015-08-06 利用25-羟基维生素d的辅助疗法
CN201580047452.8A Pending CN106604733A (zh) 2014-08-07 2015-08-06 利用25‑羟基维生素d的辅助疗法

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CN201580047452.8A Pending CN106604733A (zh) 2014-08-07 2015-08-06 利用25‑羟基维生素d的辅助疗法

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US (2) US20180085381A1 (enExample)
EP (1) EP3193925A2 (enExample)
JP (5) JP2017523220A (enExample)
KR (2) KR20170047265A (enExample)
CN (2) CN114681468A (enExample)
AU (2) AU2015298858A1 (enExample)
BR (1) BR112017002526A2 (enExample)
CA (1) CA2957240A1 (enExample)
CL (1) CL2017000317A1 (enExample)
CO (2) CO2018004206A2 (enExample)
CR (2) CR20210577A (enExample)
EA (1) EA201790332A1 (enExample)
EC (1) ECSP17014159A (enExample)
IL (1) IL250462A0 (enExample)
MX (1) MX2017001751A (enExample)
MY (1) MY203284A (enExample)
PE (1) PE20170392A1 (enExample)
PH (2) PH12017500228A1 (enExample)
SG (2) SG11201700858RA (enExample)
TW (2) TWI778934B (enExample)
WO (1) WO2016020508A2 (enExample)

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SI1993559T1 (sl) 2006-02-03 2017-01-31 Opko Renal, Llc Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3
PT2679228T (pt) 2006-06-21 2018-04-16 Opko Ireland Global Holdings Ltd Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d
CN104257667B (zh) 2007-04-25 2019-06-04 欧普科Ip 控股Ii 有限公司 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的方法和组合物
KR101959952B1 (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
ES2783980T3 (es) 2010-03-29 2020-09-21 Opko Ireland Global Holdings Ltd Métodos y composiciones para la reducción de niveles de paratiroides
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US10220047B2 (en) * 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
MY198547A (en) 2016-03-28 2023-09-04 Opko Ireland Global Holdings Ltd Methods of vitamin d treatment
ES2893753T3 (es) * 2016-05-20 2022-02-10 Christoph Karl Composiciones farmacéuticas con ácido zoledrónico, calcio y vitamina D, adecuadas para el tratamiento y/o la profilaxis de enfermedades del metabolismo óseo y de efectos secundarios inducidos por la terapia, tales como hipocalcemias
DE202017007721U1 (de) * 2016-05-20 2025-02-11 Christoph Karl Pharmazeutische Zusammensetzungen mit Anti-RANKL-Antikörpern, Kalzium und Vitamin D, geeignet zur Behandlung und/oder Prophylaxe von Erkrankungen des Knochenstoffwechsels und von therapiebedingten Nebenwirkungen wie Hypokalzämien
CN108519448B (zh) * 2018-04-04 2021-04-13 北京市心肺血管疾病研究所 25-羟基维生素d在制备大动脉炎患者疾病活动性评判试剂盒中的应用
KR20210054539A (ko) 2018-08-31 2021-05-13 옵코 아일랜드 글로벌 홀딩스 리미티드 비타민 d의 소아용 투여 형태, 이의 제조 및 사용
WO2021205225A1 (en) * 2020-04-06 2021-10-14 Eirgen Pharma Ltd. 25-hydroxyvitamin d for the treatment of sars-cov-2 infection
WO2025094144A1 (en) 2023-11-02 2025-05-08 Eirgen Pharma Ltd. Controlling loss of kidney function

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