KR20170040805A - 히스톤 데메틸라제를 억제하기 위한 화합물 및 방법 - Google Patents

히스톤 데메틸라제를 억제하기 위한 화합물 및 방법 Download PDF

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KR20170040805A
KR20170040805A KR1020177006855A KR20177006855A KR20170040805A KR 20170040805 A KR20170040805 A KR 20170040805A KR 1020177006855 A KR1020177006855 A KR 1020177006855A KR 20177006855 A KR20177006855 A KR 20177006855A KR 20170040805 A KR20170040805 A KR 20170040805A
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South Korea
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alkyl
cycloalkyl
aryl
heteroaryl
alkenyl
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Korean (ko)
Inventor
토마스 뵈센
마크 라벨
잉 양
니르자 사라스와트
다스타기리 두데쿨라
시릴 존 쿡
람크리시나 레디 바키티
루이 장
파르만 울라
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길리애드 사이언시즈, 인코포레이티드
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Publication of KR20170040805A publication Critical patent/KR20170040805A/ko
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
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KR1020177006855A 2014-08-27 2015-08-26 히스톤 데메틸라제를 억제하기 위한 화합물 및 방법 Withdrawn KR20170040805A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462042717P 2014-08-27 2014-08-27
US62/042,717 2014-08-27
PCT/US2015/046921 WO2016033169A1 (en) 2014-08-27 2015-08-26 Compounds and methods for inhibiting histone demethylases

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US (1) US9802941B2 (OSRAM)
EP (1) EP3186238A1 (OSRAM)
JP (1) JP2017526675A (OSRAM)
KR (1) KR20170040805A (OSRAM)
CN (1) CN107074807A (OSRAM)
AR (1) AR101692A1 (OSRAM)
AU (1) AU2015306662A1 (OSRAM)
BR (1) BR112017003442A2 (OSRAM)
CA (1) CA2957947A1 (OSRAM)
EA (1) EA201790154A1 (OSRAM)
IL (1) IL250355A0 (OSRAM)
MA (1) MA40470A (OSRAM)
MX (1) MX2017002451A (OSRAM)
SG (1) SG11201701182VA (OSRAM)
TW (1) TW201625536A (OSRAM)
WO (1) WO2016033169A1 (OSRAM)

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WO2017198785A1 (en) * 2016-05-18 2017-11-23 Ieo - Istituto Europeo Di Oncologia S.R.L. Oxime derivatives useful as inhibitors of histone demethylase kdm4c
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