KR20160092991A - Irak 억제제 및 이의 용도 - Google Patents

Irak 억제제 및 이의 용도 Download PDF

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Publication number
KR20160092991A
KR20160092991A KR1020167011026A KR20167011026A KR20160092991A KR 20160092991 A KR20160092991 A KR 20160092991A KR 1020167011026 A KR1020167011026 A KR 1020167011026A KR 20167011026 A KR20167011026 A KR 20167011026A KR 20160092991 A KR20160092991 A KR 20160092991A
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Prior art keywords
disease
compound
compounds
ring
irak
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Korean (ko)
Inventor
도나 엘. 로메로
크레이그 이. 매세이
쇼네시 로빈슨
제레미 로버트 그린우드
제럴딘 해리먼
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님버스 아이리스 인코포레이티드
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Publication of KR20160092991A publication Critical patent/KR20160092991A/ko
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
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  • Pharmacology & Pharmacy (AREA)
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  • Obesity (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
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KR1020167011026A 2013-09-27 2014-09-25 Irak 억제제 및 이의 용도 Withdrawn KR20160092991A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361883497P 2013-09-27 2013-09-27
US61/883,497 2013-09-27
PCT/US2014/057444 WO2015048281A1 (en) 2013-09-27 2014-09-25 Irak inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
KR20160092991A true KR20160092991A (ko) 2016-08-05

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KR1020167011026A Withdrawn KR20160092991A (ko) 2013-09-27 2014-09-25 Irak 억제제 및 이의 용도

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US (2) US9518065B2 (https=)
EP (1) EP3049086A4 (https=)
JP (1) JP2016531870A (https=)
KR (1) KR20160092991A (https=)
CN (1) CN106232122A (https=)
BR (1) BR112016006319A2 (https=)
CA (1) CA2925211A1 (https=)
MX (1) MX2016003843A (https=)
RU (1) RU2016110852A (https=)
TW (1) TW201522349A (https=)
WO (1) WO2015048281A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017004133A1 (en) * 2015-06-29 2017-01-05 Nimbus Iris, Inc. Irak inhibitors and uses thereof
MX384172B (es) * 2015-08-04 2025-03-14 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Derivados de pirazol pirimidina y sus usos.
JP6994454B2 (ja) 2015-08-04 2022-01-14 ライジェル ファーマシューティカルズ, インコーポレイテッド ベンズアゾール化合物ならびに該化合物の作製方法および使用方法
KR102048719B1 (ko) * 2015-08-13 2019-11-26 베이징 한미 파마슈티컬 컴퍼니 리미티드 Irak4억제제 및 이의 용도
KR102110573B1 (ko) * 2015-08-13 2020-05-13 베이징 한미 파마슈티컬 컴퍼니 리미티드 Irak4억제제 및 이의 용도
GB201518456D0 (en) * 2015-10-19 2015-12-02 Galapagos Nv Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory, autoimmune and/or proliferative diseases
SG10201508795XA (en) * 2015-10-23 2017-05-30 Agency Science Tech & Res Method for treating cancer
WO2017205766A1 (en) * 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
WO2017205762A1 (en) * 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
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