KR20160087898A - 항­감염 방법，조성물，및 장치 - Google Patents

항­감염 방법，조성물，및 장치 Download PDF

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Publication number
KR20160087898A
KR20160087898A KR1020167016606A KR20167016606A KR20160087898A KR 20160087898 A KR20160087898 A KR 20160087898A KR 1020167016606 A KR1020167016606 A KR 1020167016606A KR 20167016606 A KR20167016606 A KR 20167016606A KR 20160087898 A KR20160087898 A KR 20160087898A
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South Korea
Prior art keywords
epinaconazole
nail
formulation
treatment
weeks
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Ceased
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KR1020167016606A
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English (en)
Korean (ko)
Inventor
라드하크리쉬난 필라이
고든 도우
Original Assignee
다우 파마슈티컬 사이언시즈, 인코포레이티드
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Priority to KR1020237003019A priority Critical patent/KR102612453B1/ko
Publication of KR20160087898A publication Critical patent/KR20160087898A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00—Cutting
    • Y10T83/04—Processes
    • Y10T83/0405—With preparatory or simultaneous ancillary treatment of work
    • Y10T83/0443—By fluid application

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020167016606A 2013-11-22 2014-11-24 항­감염 방법，조성물，및 장치 Ceased KR20160087898A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237003019A KR102612453B1 (ko) 2013-11-22 2014-11-24 항­감염 방법，조성물，및 장치

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361907401P 2013-11-22 2013-11-22
US61/907,401 2013-11-22
PCT/US2014/067184 WO2015077729A2 (en) 2013-11-22 2014-11-24 Anti-infective methods, compositions, and devices

Related Child Applications (1)

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KR1020237003019A Division KR102612453B1 (ko) 2013-11-22 2014-11-24 항­감염 방법，조성물，및 장치

Publications (1)

Publication Number Publication Date
KR20160087898A true KR20160087898A (ko) 2016-07-22

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KR1020167016606A Ceased KR20160087898A (ko) 2013-11-22 2014-11-24 항­감염 방법，조성물，및 장치
KR1020237003019A Active KR102612453B1 (ko) 2013-11-22 2014-11-24 항­감염 방법，조성물，및 장치

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Country Status (7)

Country Link
US (4) US10245257B2 (enExample)
EP (1) EP3071295A4 (enExample)
JP (2) JP6611014B2 (enExample)
KR (2) KR20160087898A (enExample)
CN (2) CN112999223A (enExample)
CA (2) CA2931144C (enExample)
WO (1) WO2015077729A2 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020246654A1 (ko) * 2019-06-07 2020-12-10 주식회사 바이오빌리프 에피나코나졸을 함유하는 용액 형태의 국소 투여용 약학 조성물
KR102217617B1 (ko) 2020-08-14 2021-02-19 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
WO2021054532A3 (ko) * 2019-09-17 2021-05-14 주식회사 바이오빌리프 킬레이트화제를 포함하는 안정화된 에피나코나졸-함유 약학 조성물
WO2021054534A3 (ko) * 2019-09-17 2021-05-14 주식회사 바이오빌리프 킬레이트화제 및 항산화제의 조합을 포함하는 안정화된 에피나코나졸-함유 약학 조성물
WO2021054531A3 (ko) * 2019-09-17 2021-05-14 주식회사 바이오빌리프 항산화제를 포함하는 안정화된 에피나코나졸-함유 약학 조성물
WO2021054535A3 (ko) * 2019-09-17 2021-05-14 주식회사 바이오빌리프 킬레이트화제, 항산화제, 및 산의 조합을 포함하는 안정화된 에피나코나졸-함유 약학 조성물
WO2021054533A3 (ko) * 2019-09-17 2021-05-14 주식회사 바이오빌리프 산으로서 소르빈산을 포함하는 안정화된 에피나코나졸-함유 약학 조성물
WO2021054536A3 (ko) * 2019-09-17 2021-05-14 주식회사 바이오빌리프 에피나코나졸을 함유하는 안정화된 약학 조성물
KR20210117904A (ko) * 2020-03-19 2021-09-29 동아에스티 주식회사 에피나코나졸을 함유하는 국소 투여용 약학 조성물
WO2022035031A1 (ko) * 2020-08-14 2022-02-17 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
WO2023121421A1 (ko) * 2021-12-23 2023-06-29 신신제약 주식회사 에피나코나졸을 함유하는 조갑 진균증 치료용 조성물

Families Citing this family (11)

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CN105683184B (zh) 2013-10-03 2019-05-10 道尔医药科学公司 稳定的艾菲康唑组合物
CA2931144C (en) * 2013-11-22 2020-02-04 Dow Pharmaceutical Sciences, Inc. Anti-infective methods, compositions, and devices
CN106918672B (zh) * 2015-12-28 2021-02-09 中美华世通生物医药科技（武汉）有限公司 利用hplc测定艾氟康唑原料药及其制剂中有关物质的方法
WO2019088005A1 (ja) * 2017-10-30 2019-05-09 科研製薬株式会社 爪白癬治療用の外用製剤
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KR20220119363A (ko) * 2019-12-24 2022-08-29 가껭세이야꾸가부시기가이샤 에피나코나졸을 함유하는 의약
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US20230346101A1 (en) * 2022-04-29 2023-11-02 Distinct Dermatology Inc. Treatment of fungal nail infection

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WO2022035031A1 (ko) * 2020-08-14 2022-02-17 비엘엔에이치 주식회사 백선의 예방 또는 치료용 약학적 조성물
WO2023121421A1 (ko) * 2021-12-23 2023-06-29 신신제약 주식회사 에피나코나졸을 함유하는 조갑 진균증 치료용 조성물

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