KR20160058889A - 치환된 아미노피리미딘 화합물 및 이용 방법 - Google Patents

치환된 아미노피리미딘 화합물 및 이용 방법 Download PDF

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Publication number
KR20160058889A
KR20160058889A KR1020167010188A KR20167010188A KR20160058889A KR 20160058889 A KR20160058889 A KR 20160058889A KR 1020167010188 A KR1020167010188 A KR 1020167010188A KR 20167010188 A KR20167010188 A KR 20167010188A KR 20160058889 A KR20160058889 A KR 20160058889A
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South Korea
Prior art keywords
alkylene
heterocyclyl
alkyl
compound
cycloalkyl
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KR1020167010188A
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English (en)
Korean (ko)
Inventor
닝 시
량 왕
쭈핑 우
쉐진 펑
옌쥔 우
Original Assignee
칼리토르 사이언시즈, 엘엘씨
선샤인 레이크 파르마 컴퍼니 리미티드
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Publication of KR20160058889A publication Critical patent/KR20160058889A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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  • Health & Medical Sciences (AREA)
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  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Neurosurgery (AREA)
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  • Virology (AREA)
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  • Diabetes (AREA)
  • Hematology (AREA)
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  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
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KR1020167010188A 2013-09-22 2014-09-17 치환된 아미노피리미딘 화합물 및 이용 방법 Ceased KR20160058889A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361880974P 2013-09-22 2013-09-22
US61/880,974 2013-09-22
US201461983444P 2014-04-23 2014-04-23
US61/983,444 2014-04-23
PCT/US2014/055966 WO2015042077A1 (en) 2013-09-22 2014-09-17 Substituted aminopyrimidine compounds and methods of use

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KR20160058889A true KR20160058889A (ko) 2016-05-25

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KR1020167010190A Ceased KR20160060100A (ko) 2013-09-22 2014-09-17 치환된 아미노피리미딘 화합물 및 이용 방법

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US (4) US9657007B2 (https=)
EP (2) EP3046921A4 (https=)
JP (2) JP6494634B2 (https=)
KR (2) KR20160058889A (https=)
AU (2) AU2014321419B2 (https=)
BR (1) BR112016003229A8 (https=)
CA (2) CA2920059A1 (https=)
MX (2) MX2016003457A (https=)
MY (2) MY176421A (https=)
RU (2) RU2675105C9 (https=)
SG (2) SG11201600028YA (https=)
WO (3) WO2015042078A2 (https=)

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