KR20150129011A - 고체상 펩티드 합성 방법 및 연관 시스템 - Google Patents

고체상 펩티드 합성 방법 및 연관 시스템 Download PDF

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KR20150129011A
KR20150129011A KR1020157029308A KR20157029308A KR20150129011A KR 20150129011 A KR20150129011 A KR 20150129011A KR 1020157029308 A KR1020157029308 A KR 1020157029308A KR 20157029308 A KR20157029308 A KR 20157029308A KR 20150129011 A KR20150129011 A KR 20150129011A
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amino acid
peptide
immobilized peptide
immobilized
solid support
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Korean (ko)
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마크 데이빗 사이먼
브래들리 엘. 펜텔루트
앤드리어 아다모
패트릭 루이스 헤이더
클라브스 에프. 젠슨
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메사추세츠 인스티튜트 오브 테크놀로지
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053—Details of the reactor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
KR1020157029308A 2013-03-15 2014-02-24 고체상 펩티드 합성 방법 및 연관 시스템 Withdrawn KR20150129011A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/833,745 2013-03-15
US13/833,745 US9169287B2 (en) 2013-03-15 2013-03-15 Solid phase peptide synthesis processes and associated systems
PCT/US2014/017970 WO2014149387A2 (en) 2013-03-15 2014-02-24 Solid phase peptide synthesis processes and associated systems

Publications (1)

Publication Number Publication Date
KR20150129011A true KR20150129011A (ko) 2015-11-18

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Family Applications (1)

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KR1020157029308A Withdrawn KR20150129011A (ko) 2013-03-15 2014-02-24 고체상 펩티드 합성 방법 및 연관 시스템

Country Status (10)

Country Link
US (9) US9169287B2 (enExample)
EP (2) EP2970374B1 (enExample)
JP (4) JP6423849B2 (enExample)
KR (1) KR20150129011A (enExample)
CN (2) CN110885355A (enExample)
AU (1) AU2014238203B2 (enExample)
CA (1) CA2904355A1 (enExample)
DK (1) DK2970374T3 (enExample)
SG (2) SG11201507527WA (enExample)
WO (1) WO2014149387A2 (enExample)

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CN108290923A (zh) 2015-09-17 2018-07-17 麻省理工学院 用于固相肽合成的方法和系统
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CN112111001B (zh) * 2019-06-19 2021-10-29 翰宇药业（武汉）有限公司 胸腺肽Tα-1的合成方法
CN110343147B (zh) * 2019-08-22 2021-07-02 凯莱英医药集团（天津）股份有限公司 艾替班特的合成方法
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EP4247830A1 (en) * 2020-11-17 2023-09-27 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Extremely fast solid phase synthesis
US20220165359A1 (en) 2020-11-23 2022-05-26 Peptilogics, Inc. Generating anti-infective design spaces for selecting drug candidates
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US11512345B1 (en) 2021-05-07 2022-11-29 Peptilogics, Inc. Methods and apparatuses for generating peptides by synthesizing a portion of a design space to identify peptides having non-canonical amino acids
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WO2025071365A1 (ko) * 2023-09-27 2025-04-03 에스피투티엑스주식회사 흐름 반응기 및 이를 포함하는 생물학적 고분자 합성 시스템
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AU2014238203A1 (en) 2015-10-15
EP2970374A2 (en) 2016-01-20
US20210188899A1 (en) 2021-06-24
US9868759B2 (en) 2018-01-16
US10889613B2 (en) 2021-01-12
SG10201801611SA (en) 2018-04-27
US20160102118A1 (en) 2016-04-14
DK2970374T3 (da) 2020-02-10
JP7323275B2 (ja) 2023-08-08
EP3626726A3 (en) 2020-07-29
US11878996B2 (en) 2024-01-23
CA2904355A1 (en) 2014-09-25
US20180066012A1 (en) 2018-03-08
WO2014149387A3 (en) 2014-11-27
US20180057525A1 (en) 2018-03-01
CN105164145B (zh) 2019-12-13
CN105164145A (zh) 2015-12-16
JP2019023226A (ja) 2019-02-14
JP2016515114A (ja) 2016-05-26
JP6423849B2 (ja) 2018-11-14
CN110885355A (zh) 2020-03-17
EP2970374B1 (en) 2019-11-06
JP2021119204A (ja) 2021-08-12
EP3626726A2 (en) 2020-03-25
US10988504B2 (en) 2021-04-27
US20140275481A1 (en) 2014-09-18
US20220275021A1 (en) 2022-09-01
SG11201507527WA (en) 2015-10-29
AU2014238203B2 (en) 2018-08-23
JP2024020587A (ja) 2024-02-14
US9169287B2 (en) 2015-10-27
US20240383944A1 (en) 2024-11-21
US20210188900A1 (en) 2021-06-24
US20240368216A1 (en) 2024-11-07
WO2014149387A8 (en) 2015-10-15
WO2014149387A2 (en) 2014-09-25

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PA0105 International application

Patent event date: 20151014

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid