KR20140019342A - 포스포디에스테라제 억제제로서의 (1,2,4)트리아졸로[4,3-a]퀴녹살린 유도체 - Google Patents

포스포디에스테라제 억제제로서의 (1,2,4)트리아졸로[4,3-a]퀴녹살린 유도체 Download PDF

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KR20140019342A
KR20140019342A KR1020137023101A KR20137023101A KR20140019342A KR 20140019342 A KR20140019342 A KR 20140019342A KR 1020137023101 A KR1020137023101 A KR 1020137023101A KR 20137023101 A KR20137023101 A KR 20137023101A KR 20140019342 A KR20140019342 A KR 20140019342A
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South Korea
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compound
methyl
triazolo
formula
quinoxaline
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Ceased
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KR1020137023101A
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Korean (ko)
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한스-요아힘 란카우
바르바라 란겐
크리스티안 그룬발트
노르베르트 회프겐
한스 슈탕게
리타 도스트
우테 에거란트
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베링거 인겔하임 인터내셔날 게엠베하
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Publication of KR20140019342A publication Critical patent/KR20140019342A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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KR1020137023101A 2011-01-31 2012-01-31 포스포디에스테라제 억제제로서의 (1,2,4)트리아졸로[4,3-a]퀴녹살린 유도체 Ceased KR20140019342A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161437848P 2011-01-31 2011-01-31
US61/437,848 2011-01-31
PCT/EP2012/051546 WO2012104293A1 (en) 2011-01-31 2012-01-31 (1,2,4)triazolo[4,3-a]quinoxaline derivatives as inhibitors of phosphodiesterases

Publications (1)

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KR20140019342A true KR20140019342A (ko) 2014-02-14

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KR1020137023101A Ceased KR20140019342A (ko) 2011-01-31 2012-01-31 포스포디에스테라제 억제제로서의 (1,2,4)트리아졸로[4,3-a]퀴녹살린 유도체

Country Status (25)

Country Link
US (1) US9540379B2 (https=)
EP (1) EP2670754B1 (https=)
JP (1) JP6027547B2 (https=)
KR (1) KR20140019342A (https=)
CN (1) CN103459395A (https=)
AR (1) AR085099A1 (https=)
AU (1) AU2012213471B2 (https=)
BR (1) BR112013019354A2 (https=)
CA (1) CA2824929A1 (https=)
CL (1) CL2013002003A1 (https=)
CO (1) CO6811848A2 (https=)
EA (1) EA023792B1 (https=)
EC (1) ECSP13012824A (https=)
GE (1) GEP20156333B (https=)
IL (1) IL226826A (https=)
MA (1) MA34844B1 (https=)
MX (1) MX2013008667A (https=)
PE (1) PE20141023A1 (https=)
PH (1) PH12013501355A1 (https=)
SG (1) SG192210A1 (https=)
TN (1) TN2013000325A1 (https=)
TW (1) TWI535718B (https=)
UA (1) UA111963C2 (https=)
UY (1) UY33888A (https=)
WO (1) WO2012104293A1 (https=)

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NZ611630A (en) 2015-03-27
AR085099A1 (es) 2013-09-11
US9540379B2 (en) 2017-01-10
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JP6027547B2 (ja) 2016-11-16
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EA201300871A1 (ru) 2014-01-30
UA111963C2 (uk) 2016-07-11
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