KR20120127495A - 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체 - Google Patents

8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체 Download PDF

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KR20120127495A
KR20120127495A KR1020127023813A KR20127023813A KR20120127495A KR 20120127495 A KR20120127495 A KR 20120127495A KR 1020127023813 A KR1020127023813 A KR 1020127023813A KR 20127023813 A KR20127023813 A KR 20127023813A KR 20120127495 A KR20120127495 A KR 20120127495A
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salt
polymorph
campylate
compound
ppm
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페트리시아 안 바스포드
앤서니 마이클 캠페타
아담 길모어
매튜 카메론 존스
엘레페리오스 고굴로스
수만 루스라
로버트 왈튼
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화이자 인코포레이티드
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KR1020127023813A 2010-02-12 2011-02-10 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체 Ceased KR20120127495A (ko)

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Application Number Priority Date Filing Date Title
US30427710P 2010-02-12 2010-02-12
US61/304,277 2010-02-12
PCT/IB2011/050571 WO2011098971A1 (en) 2010-02-12 2011-02-10 Salts and polymorphs of 8-fluoro-2-{4-[(methylamino}methyl]phenyl}-1,3,4,5-tetrahydro-6h-azepino[5,4,3-cd]indol-6-one

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KR1020197005968A Division KR102108226B1 (ko) 2010-02-12 2011-02-10 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체

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KR20120127495A true KR20120127495A (ko) 2012-11-21

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KR1020127023813A Ceased KR20120127495A (ko) 2010-02-12 2011-02-10 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체
KR1020197005968A Active KR102108226B1 (ko) 2010-02-12 2011-02-10 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체

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KR1020197005968A Active KR102108226B1 (ko) 2010-02-12 2011-02-10 8-플루오로-2-｛4-［(메틸아미노)메틸］페닐｝-1,3,4,5-테트라하이드로-6ｈ-아제피노［5,4,3-ｃｄ］인돌-6-온의 염 및 다형체

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US (5) US8754072B2 (https=)
EP (4) EP2534153B2 (https=)
JP (6) JP5745283B2 (https=)
KR (2) KR20120127495A (https=)
CN (2) CN102884066B (https=)
AR (2) AR080164A1 (https=)
AU (1) AU2011213944B2 (https=)
BR (1) BR112012019050B1 (https=)
CA (2) CA3024216C (https=)
CY (3) CY1118319T1 (https=)
DK (2) DK2534153T4 (https=)
ES (2) ES2753748T3 (https=)
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HR (2) HRP20161742T4 (https=)
HU (3) HUE047248T2 (https=)
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LT (3) LT3150610T (https=)
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MX (1) MX343383B (https=)
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NO (1) NO2018039I1 (https=)
NZ (1) NZ601445A (https=)
PL (2) PL3150610T3 (https=)
PT (2) PT3150610T (https=)
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SG (2) SG182533A1 (https=)
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TW201516636A (zh) * 2013-10-22 2015-05-01 鴻海精密工業股份有限公司 電子裝置及其供電方法
KR102803917B1 (ko) * 2014-08-22 2025-05-07 파르마＆ 슈바이츠 게엠베하 루카파립의 고 용량 강도 정제
CA3025049A1 (en) 2016-05-16 2017-11-23 Pulmagen Therapeutics (Asthma) Limited Crystal of quinoline derivative
DE102016218772A1 (de) * 2016-09-28 2018-03-29 Bruker Biospin Gmbh Verbesserte Temperierung eines NMR-MAS-Rotors
US10875870B2 (en) 2017-01-24 2020-12-29 Assia Chemical Industries Ltd. Solid state forms of rucaparib and of rucaparib salts
CN109651377B (zh) * 2017-10-12 2020-10-20 成都海创药业有限公司 一种治疗癌症的化合物及其用途
JP2021501771A (ja) * 2017-11-03 2021-01-21 サンド・アクチエンゲゼルシヤフト 三環系ポリ（ａｄｐ−リボース）ポリメラーゼ阻害剤の結晶性塩
WO2019115000A1 (en) * 2017-12-15 2019-06-20 Advitech Advisory And Technologies Sa Process for the preparation of rucaparib and novel synthesis intermediates
WO2019130229A1 (en) 2017-12-28 2019-07-04 Mylan Laboratories Ltd Methods and intermediates for preparing rucaparib
KR20200121800A (ko) 2018-01-05 2020-10-26 싸이브렉사 1, 인크. 산성 또는 저산소성 질환에 걸린 조직에 관련된 질환의 치료를 위한 화합물, 조성물 및 방법
US10442813B2 (en) 2018-01-30 2019-10-15 RK Pharma Solutions LLC Polymorphs of rucaparib camsylate and methods of making same
WO2019207498A1 (en) * 2018-04-25 2019-10-31 Biophore India Pharmaceuticals Pvt. Ltd Solid forms of 8-fluoro-2-{4-[(methylamino)methyl] phenyl}-1,3,4,5-tetrahydro-6h-azepino[5,4,3-cd] indol-6-one ((1s,4r)-7,7dimethyl-2-oxobicyclo [2.2.1] hept-1-yl) methanesulfonic acid salt (rucaparib camsylate) and the prerparation thereof
WO2019207596A1 (en) 2018-04-25 2019-10-31 Mylan Laboratories Limited Novel crystalline forms of rucaparib (s)-camsylate salt and rucaparib free base
CN108743557A (zh) * 2018-06-27 2018-11-06 李莉 一种磷酸瑞卡帕布软胶囊及其制备方法
CN109111454A (zh) * 2018-08-01 2019-01-01 宁波金未生物科技有限公司 一种瑞卡帕布s-樟脑磺酸盐
CR20210281A (es) 2018-10-30 2021-10-25 Repare Therapeutics Inc Compuestos, composiciones farmacéuticas y métodos de preparación de compuestos y de uso como inhibidores de la cinasa atr
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