KR20120118045A - 효모 세포 표면상에 폴리펩티드를 디스플레이하기 위한 방법들 및 조성물들 - Google Patents

효모 세포 표면상에 폴리펩티드를 디스플레이하기 위한 방법들 및 조성물들 Download PDF

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KR20120118045A
KR20120118045A KR1020127021903A KR20127021903A KR20120118045A KR 20120118045 A KR20120118045 A KR 20120118045A KR 1020127021903 A KR1020127021903 A KR 1020127021903A KR 20127021903 A KR20127021903 A KR 20127021903A KR 20120118045 A KR20120118045 A KR 20120118045A
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polypeptide
antibody polypeptide
fragment
antibody
yarrowia
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스테판 리카에르트
기욤 레론델
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옥시레인 유케이 리미티드
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C12N15/1034Isolating an individual clone by screening libraries
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    • C12N15/09Recombinant DNA-technology
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    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/55Fab or Fab'
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020127021903A 2010-01-21 2011-01-21 효모 세포 표면상에 폴리펩티드를 디스플레이하기 위한 방법들 및 조성물들 Withdrawn KR20120118045A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29709310P 2010-01-21 2010-01-21
US61/297,093 2010-01-21

Publications (1)

Publication Number Publication Date
KR20120118045A true KR20120118045A (ko) 2012-10-25

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KR1020127021903A Withdrawn KR20120118045A (ko) 2010-01-21 2011-01-21 효모 세포 표면상에 폴리펩티드를 디스플레이하기 위한 방법들 및 조성물들

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US (1) US20130096281A1 (enExample)
EP (1) EP2526193A1 (enExample)
JP (1) JP2013517761A (enExample)
KR (1) KR20120118045A (enExample)
CN (1) CN102803491A (enExample)
BR (1) BR112012018163A2 (enExample)
CA (1) CA2787677A1 (enExample)
SG (1) SG182647A1 (enExample)
WO (1) WO2011089527A1 (enExample)

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JP5990102B2 (ja) 2009-09-29 2016-09-07 ユニフェルシテイト ヘント ホスホ−6−マンノースへのマンノース−1−ホスホ−6−マンノース結合の加水分解
BR112012011980A2 (pt) 2009-11-19 2021-09-08 Oxyrane Uk Limited Métodos de produzir células transformadas de yarrowia lipolytica e proteínas-alvocompreendendo n-glicanos, células transformadas de yarrowia lipolytica e suas culturas, bem como composição compreendendo glicoproteínas
SG189110A1 (en) 2010-09-29 2013-05-31 Oxyrane Uk Ltd De-mannosylation of phosphorylated n-glycans
CA2812870C (en) 2010-09-29 2020-06-09 Oxyrane Uk Limited Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins
US20140243234A1 (en) * 2011-08-03 2014-08-28 Texas Biomedical Research Institute Nucleic acid compositions, methods and kits for rapid pairing of affinity agents
CN104379162B (zh) 2012-03-15 2017-03-15 奥克西雷恩英国有限公司 用于治疗蓬佩氏病的方法和材料
KR102150414B1 (ko) * 2013-09-18 2020-09-02 리제너론 파마슈티칼스 인코포레이티드 히스티딘 엔지니어링된 경쇄 항체 및 그것을 생성하기 위한 유전자 변형된 비-인간 동물
HRP20201906T1 (hr) 2013-12-20 2021-04-02 Fred Hutchinson Cancer Research Center Označene kimerne efektorske molekule i njihovi receptori
WO2016075314A1 (fr) 2014-11-13 2016-05-19 Institut National De La Recherche Agronomique Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
US20160185633A1 (en) * 2014-12-30 2016-06-30 University Of Florida Research Foundation, Inc. Recovery of nutrients from water and wastewater by precipitation as struvite
WO2016176652A2 (en) 2015-04-29 2016-11-03 Fred Hutchinson Cancer Research Center Modified stem cells and uses thereof
EA201891521A1 (ru) * 2016-01-08 2019-01-31 ДСМ АйПи АССЕТС Б.В. Переключение типа спаривания у yarrowia lipolytica
US10988759B2 (en) 2016-01-15 2021-04-27 University Of Washington High throughput protein-protein interaction screening in yeast liquid culture
CN106701606B (zh) * 2016-12-19 2021-03-26 广东利世康低碳科技有限公司 一种能降解利用餐厨废弃物的基因工程产朊假丝酵母及其构建方法
CN108085332B (zh) * 2017-12-27 2020-11-27 中国科学院青岛生物能源与过程研究所 一种细胞表面展示有豆壳过氧化物酶的重组酵母菌及其构建方法与应用
FR3081169B1 (fr) 2018-05-15 2020-06-19 Messenger Biopharma Substitution de la coiffe des arn messagers par deux sequences d'arn introduites a leur extremite 5'
WO2021231013A1 (en) * 2020-05-11 2021-11-18 A-Alpha Bio, Inc. High-throughput screening methods to identify small molecule targets
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CN111996132A (zh) * 2020-07-21 2020-11-27 郑州大学 一种解脂耶氏酵母表面展示方法
WO2023051972A1 (en) 2021-09-29 2023-04-06 Miltenyi Biotec B.V. & Co. KG Method for the generation and selection of a producer cell
CN114606151B (zh) * 2022-04-27 2023-05-19 南京工业大学 一种表面展示β-半乳糖苷酶的重组毕赤酵母及构建方法和应用
CN115851460A (zh) * 2022-08-10 2023-03-28 丁辰 一种具有激活哺乳动物干细胞分化功能的菌株、组合物及其应用
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WO2011089527A1 (en) 2011-07-28
CN102803491A (zh) 2012-11-28
CA2787677A1 (en) 2011-07-28
JP2013517761A (ja) 2013-05-20
SG182647A1 (en) 2012-08-30
EP2526193A1 (en) 2012-11-28
BR112012018163A2 (pt) 2019-09-24
US20130096281A1 (en) 2013-04-18

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Patent event date: 20120821

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