KR20120107451A - 발효유 제품 제조 방법 - Google Patents

발효유 제품 제조 방법 Download PDF

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Publication number
KR20120107451A
KR20120107451A KR1020127000366A KR20127000366A KR20120107451A KR 20120107451 A KR20120107451 A KR 20120107451A KR 1020127000366 A KR1020127000366 A KR 1020127000366A KR 20127000366 A KR20127000366 A KR 20127000366A KR 20120107451 A KR20120107451 A KR 20120107451A
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KR
South Korea
Prior art keywords
lactobacillus
species
strain
belonging
producing
Prior art date
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Ceased
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KR1020127000366A
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English (en)
Korean (ko)
Inventor
디테 마리 폴켄베르크
론 파울센
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시에이치알. 한센 에이/에스
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Publication of KR20120107451A publication Critical patent/KR20120107451A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/127—Fermented milk preparations; Treatment using microorganisms or enzymes using microorganisms of the genus lactobacteriaceae and other microorganisms or enzymes, e.g. kefir, koumiss
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1238—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt using specific L. bulgaricus or S. thermophilus microorganisms; using entrapped or encapsulated yoghurt bacteria; Physical or chemical treatment of L. bulgaricus or S. thermophilus cultures; Fermentation only with L. bulgaricus or only with S. thermophilus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/127—Fermented milk preparations; Treatment using microorganisms or enzymes using microorganisms of the genus lactobacteriaceae and other microorganisms or enzymes, e.g. kefir, koumiss
    • A23C9/1275—Fermented milk preparations; Treatment using microorganisms or enzymes using microorganisms of the genus lactobacteriaceae and other microorganisms or enzymes, e.g. kefir, koumiss using only lactobacteriaceae for fermentation in combination with enzyme treatment of the milk product; using enzyme treated milk products for fermentation with lactobacteriaceae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/123—Bulgaricus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/143—Fermentum
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/157—Lactis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/21—Streptococcus, lactococcus
    • A23V2400/249—Thermophilus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dairy Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020127000366A 2009-06-30 2010-06-30 발효유 제품 제조 방법 Ceased KR20120107451A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200900815 2009-06-30
DKPA200900815 2009-06-30

Publications (1)

Publication Number Publication Date
KR20120107451A true KR20120107451A (ko) 2012-10-02

Family

ID=42989536

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127000366A Ceased KR20120107451A (ko) 2009-06-30 2010-06-30 발효유 제품 제조 방법

Country Status (10)

Country Link
US (2) US20120107451A1 (https=)
EP (1) EP2448420A2 (https=)
JP (1) JP2012531189A (https=)
KR (1) KR20120107451A (https=)
CN (1) CN102469804A (https=)
BR (1) BRPI1015366A2 (https=)
EA (1) EA023317B1 (https=)
MX (1) MX2011013188A (https=)
UA (1) UA106381C2 (https=)
WO (1) WO2011000879A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105713853B (zh) 2010-01-28 2020-07-17 科·汉森有限公司 基于噬菌体抗性选择的用于对食品进行质构化的乳酸细菌
BR112013009280B1 (pt) 2010-10-22 2021-08-31 Chr. Hansen A/S Método para obter uma cepa de bactérias do ácido láctico de texturização, método de produzir um laticínio e uso de uma cepa de bactérias do ácido láctico
WO2013062034A1 (ja) * 2011-10-28 2013-05-02 株式会社明治 ナチュラルチーズおよびその製造方法
CN102715247B (zh) * 2012-07-04 2013-10-23 云南农业大学 一种水牛奶干酪的加工方法
EP3133929A1 (en) * 2014-04-23 2017-03-01 DSM IP Assets B.V. Fermented milk product
US10813367B2 (en) 2014-06-19 2020-10-27 Chr. Hansen A/S Method of producing a fermented milk product with improved control of post acidification
DK2957180T3 (en) 2014-06-19 2018-05-28 Chr Hansen As Process for preparing a fermented milk product with improved post-acidification regulation
WO2017037046A1 (en) * 2015-08-31 2017-03-09 Chr. Hansen A/S Lactobacillus fermentum bacteria with antifungal activity
PE20181132A1 (es) * 2015-08-31 2018-07-17 Chr Hansen As Bacteria de lactobacillus fermentum que inhibe la posacidificacion
EP3344051A1 (en) * 2015-08-31 2018-07-11 Chr. Hansen A/S Lactobacillus fermentum bacteria reducing the concentration of acetaldehyde
CN120360151A (zh) 2017-03-28 2025-07-25 科·汉森有限公司 用于制备具有增加的天然甜味和风味的发酵食品的乳酸菌组合物
WO2019061263A1 (en) 2017-09-29 2019-04-04 Dupont Nutrition Biosciences Aps NOVEL STRAIN OF LACTOBACILLUS PLANTARUM AND USES THEREOF
CN112638163A (zh) * 2018-07-05 2021-04-09 杜邦营养生物科学有限公司 葡糖基转移酶在发酵奶基产品中提供改善的质地的用途
US11758915B2 (en) * 2018-12-21 2023-09-19 Kraft Foods Group Brands Llc Method of producing a simplified cheese spread and products therefrom
EP4340625A1 (en) 2021-05-18 2024-03-27 Chr. Hansen A/S Method of producing fermented milk products with improved texture and reduced post-acidification
WO2026003080A1 (en) 2024-06-27 2026-01-02 Chr. Hansen A/S Low post-acidifying lactic acid bacteria strains
CN120866265A (zh) * 2025-09-26 2025-10-31 杭州瑞宏生物技术有限公司 一种提高β-果糖基转移酶活力的工艺

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2518663B2 (ja) * 1987-12-24 1996-07-24 株式会社ヤクルト本社 ガラクトオリゴ糖含有加工乳の製造法
JPH0797963B2 (ja) * 1988-03-16 1995-10-25 雪印乳業株式会社 撹拌型ヨーグルトの製造方法
JP3182954B2 (ja) * 1993-01-08 2001-07-03 味の素株式会社 ヨーグルト類の製造法
US5656268A (en) * 1995-04-21 1997-08-12 Sorodsky; Michael Biological product
SE510813C2 (sv) * 1997-12-08 1999-06-28 Arla Ekonomisk Foerening Bakteriestam av arten Lactobacillus Paracasei subsp. paracasei, sammansättning därav för användning i livsmedel, samt produkt innehållande stammen
KR100753012B1 (ko) * 1999-08-03 2007-08-30 가부시키가이샤 야쿠루트 혼샤 발효유 음식품 및 그의 제조방법
EE04580B1 (et) * 2001-06-29 2006-02-15 Tartu �likool Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum
CA2476885A1 (en) * 2002-02-21 2003-08-28 Fonterra Co-Operative Group Limited Transesterification reaction for production of dairy flavour enhancing esters
US7780970B2 (en) * 2002-08-06 2010-08-24 Danisco A/S Composition
GB0218241D0 (en) * 2002-08-06 2002-09-11 Danisco Composition
KR100794702B1 (ko) * 2003-07-21 2008-01-14 (주)바이오니아 비만증 또는 당뇨병 예방 및/또는 치료용 미생물
FR2852604B1 (fr) * 2003-03-17 2005-05-13 Bacteries lactiques texturantes
CN1628530A (zh) * 2003-12-19 2005-06-22 哈尔滨美华生物技术股份有限公司 酸奶或其发酵乳饮料生产的混合菌干粉发酵剂
ITRM20040505A1 (it) * 2004-10-15 2005-01-15 Cd Invest Liofilizzati di batteri lattici e bifidobatteri ad alta dispersibilita'.
WO2007044439A2 (en) * 2005-10-05 2007-04-19 Acillix Incorporated Microbial exopolymers useful for water demineralization
JP4336992B2 (ja) * 2006-01-20 2009-09-30 日清食品ホールディングス株式会社 血中コレステロール低減作用を有する新規乳酸菌
CA2642864C (en) * 2006-02-24 2013-07-16 Chr. Hansen A/S Lactic acid bacteria providing improved texture of fermented dairy products
DK2034848T3 (en) * 2006-06-16 2017-02-06 Dupont Nutrition Biosci Aps STREPTOCOCCUS THERMOPHILUS BACTERIA
FR2906536B1 (fr) * 2006-10-03 2008-12-26 Danisco Cluster genetique de souches de streptococcus thermophilus presentant des proprietes acidifiantes et texturantes appropriees pour les fermentations laitieres.
JP2008245576A (ja) * 2007-03-30 2008-10-16 Yotsuba Nyugyo Kk 免疫調節作用が期待できる乳酸菌及び菌体外多糖類
ES2357043T3 (es) * 2007-06-06 2011-04-15 Chr. Hansen A/S Mejora del crecimiento de bifidobacterias en productos de leche fermentada .
MX2010013192A (es) * 2008-06-16 2010-12-17 Hoffmann La Roche Monoamidas heteroaromaticas como antagonistas de receptor orexinina.
CN102105065A (zh) * 2008-08-29 2011-06-22 科.汉森有限公司 发酵乳制品中双歧杆菌生长的改善

Also Published As

Publication number Publication date
JP2012531189A (ja) 2012-12-10
CN102469804A (zh) 2012-05-23
BRPI1015366A2 (pt) 2015-09-01
WO2011000879A2 (en) 2011-01-06
EP2448420A2 (en) 2012-05-09
UA106381C2 (ru) 2014-08-26
EA023317B1 (ru) 2016-05-31
US20140348980A1 (en) 2014-11-27
EA201270095A1 (ru) 2012-06-29
WO2011000879A3 (en) 2011-05-05
MX2011013188A (es) 2012-01-31
US20120107451A1 (en) 2012-05-03

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