KR20110042153A - 퓨린 ｐｉ３ｋ 억제 화합물 및 사용 방법 - Google Patents

퓨린 ｐｉ３ｋ 억제 화합물 및 사용 방법 Download PDF

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Publication number
KR20110042153A
KR20110042153A KR1020107026673A KR20107026673A KR20110042153A KR 20110042153 A KR20110042153 A KR 20110042153A KR 1020107026673 A KR1020107026673 A KR 1020107026673A KR 20107026673 A KR20107026673 A KR 20107026673A KR 20110042153 A KR20110042153 A KR 20110042153A
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purin
morpholino
compound
alkylene
methyl
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Korean (ko)
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조젯트 카스타네도
이리나 추코우리
아드리안 폴케스
다니엘 피. 서덜린
난 치 완
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제넨테크, 인크.
에프. 호프만-라 로슈 아게
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Publication of KR20110042153A publication Critical patent/KR20110042153A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020107026673A 2008-05-30 2009-05-29 퓨린 ｐｉ３ｋ 억제 화합물 및 사용 방법 Ceased KR20110042153A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5755908P 2008-05-30 2008-05-30
US61/057,559 2008-05-30

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KR20110042153A true KR20110042153A (ko) 2011-04-25

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KR1020107026673A Ceased KR20110042153A (ko) 2008-05-30 2009-05-29 퓨린 ｐｉ３ｋ 억제 화합물 및 사용 방법

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US (2) US8158624B2 (OSRAM)
EP (1) EP2279188B1 (OSRAM)
JP (1) JP2011521968A (OSRAM)
KR (1) KR20110042153A (OSRAM)
CN (1) CN102105474B (OSRAM)
AU (1) AU2009251291B2 (OSRAM)
BR (1) BRPI0909614A2 (OSRAM)
CA (1) CA2721851A1 (OSRAM)
ES (1) ES2533788T3 (OSRAM)
IL (1) IL208838A0 (OSRAM)
MX (1) MX2010012583A (OSRAM)
RU (1) RU2509081C2 (OSRAM)
WO (1) WO2009146406A1 (OSRAM)
ZA (1) ZA201007524B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180011068A (ko) * 2015-04-21 2018-01-31 구이저우 바이링 엔터프라이즈 그룹 파마슈티컬 컴퍼니 리미티드 퓨리닐-n-하이드록실 피리미딘 포름아미드 유도체, 이의 제조 방법 및 용도
KR20210069664A (ko) * 2018-09-27 2021-06-11 상하이 잉리 파마슈티컬 컴퍼니 리미티드 모르폴리노 퀴나졸린계 화합물의 결정형태, 이의 제조방법 및 용도

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BR112012011188A2 (pt) * 2009-11-12 2021-06-29 F.Hoffmann - La Roche Ag ''composto,composição farmacêutica e uso de um composto"
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US8293736B2 (en) 2010-07-14 2012-10-23 F. Hoffmann La Roche Ag Purine compounds selective for PI3K P110 delta, and methods of use
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CN103936742B (zh) * 2013-01-17 2017-05-03 程鹏 含嘌呤基的新型pi3k抑制剂及其制备方法和应用
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CN103804380B (zh) * 2014-01-24 2016-05-18 温州医科大学 以IKK-β为靶点的2-氨基-8-取代鸟嘌呤衍生物、应用及其制备方法
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PL236355B1 (pl) * 2015-04-02 2021-01-11 Celon Pharma Spolka Akcyjna Pochodne 7-(morfolin-4-ylo)pirazolo[1,5-α]pirymidyny jako inhibitory kinazy PI3
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Publication number Priority date Publication date Assignee Title
KR20180011068A (ko) * 2015-04-21 2018-01-31 구이저우 바이링 엔터프라이즈 그룹 파마슈티컬 컴퍼니 리미티드 퓨리닐-n-하이드록실 피리미딘 포름아미드 유도체, 이의 제조 방법 및 용도
KR20210069664A (ko) * 2018-09-27 2021-06-11 상하이 잉리 파마슈티컬 컴퍼니 리미티드 모르폴리노 퀴나졸린계 화합물의 결정형태, 이의 제조방법 및 용도

Also Published As

Publication number Publication date
BRPI0909614A2 (pt) 2015-09-22
RU2010154428A (ru) 2012-07-10
ES2533788T3 (es) 2015-04-14
ZA201007524B (en) 2012-01-25
US20090318411A1 (en) 2009-12-24
CN102105474B (zh) 2014-01-08
US8158624B2 (en) 2012-04-17
US20120135988A1 (en) 2012-05-31
AU2009251291A1 (en) 2009-12-03
WO2009146406A1 (en) 2009-12-03
RU2509081C2 (ru) 2014-03-10
AU2009251291B2 (en) 2013-05-02
JP2011521968A (ja) 2011-07-28
US8445487B2 (en) 2013-05-21
CN102105474A (zh) 2011-06-22
CA2721851A1 (en) 2009-12-03
EP2279188A1 (en) 2011-02-02
EP2279188B1 (en) 2015-01-28
IL208838A0 (en) 2011-01-31
MX2010012583A (es) 2011-02-24

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