KR20090080046A - pH 표적화된 약물 운반용 조성물 및 방법 - Google Patents

pH 표적화된 약물 운반용 조성물 및 방법

Info

Publication number
KR20090080046A
KR20090080046A KR1020097008031A KR20097008031A KR20090080046A KR 20090080046 A KR20090080046 A KR 20090080046A KR 1020097008031 A KR1020097008031 A KR 1020097008031A KR 20097008031 A KR20097008031 A KR 20097008031A KR 20090080046 A KR20090080046 A KR 20090080046A
Authority
KR
South Korea
Prior art keywords
composition
pharmaceutically active
active substance
integer ranging
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020097008031A
Other languages
English (en)
Korean (ko)
Inventor
다비드 레사드
라이빈 루오
도로시 레 가렉
데이먼 스미스
Original Assignee
라보팜 인코포레이트
라보팜 유럽 리미티드
라보팜(바베이도스) 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 라보팜 인코포레이트, 라보팜 유럽 리미티드, 라보팜(바베이도스) 리미티드 filed Critical 라보팜 인코포레이트
Publication of KR20090080046A publication Critical patent/KR20090080046A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C08F297/02Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type
    • C08F297/026Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type polymerising acrylic acid, methacrylic acid or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020097008031A 2006-09-22 2007-09-24 pH 표적화된 약물 운반용 조성물 및 방법 Withdrawn KR20090080046A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84635506P 2006-09-22 2006-09-22
US60/846,355 2006-09-22

Publications (1)

Publication Number Publication Date
KR20090080046A true KR20090080046A (ko) 2009-07-23

Family

ID=39153921

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097008031A Withdrawn KR20090080046A (ko) 2006-09-22 2007-09-24 pH 표적화된 약물 운반용 조성물 및 방법

Country Status (10)

Country Link
US (1) US20090258071A1 (enExample)
EP (1) EP2081548A2 (enExample)
JP (1) JP2010504318A (enExample)
KR (1) KR20090080046A (enExample)
AU (1) AU2007298674A1 (enExample)
BR (1) BRPI0716890A2 (enExample)
CA (1) CA2699184A1 (enExample)
IL (1) IL197680A0 (enExample)
MX (1) MX2009003092A (enExample)
WO (1) WO2008035229A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060198891A1 (en) 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
CA2635187A1 (en) * 2008-06-05 2009-12-05 The Royal Institution For The Advancement Of Learning/Mcgill University Oligonucleotide duplexes and uses thereof
FR2932485A1 (fr) * 2008-06-12 2009-12-18 Univ Pasteur Polymere a liberation colique specifique quel que soit le ph
US20110237686A1 (en) 2010-03-26 2011-09-29 Cerulean Pharma Inc Formulations and methods of use
US20130039864A1 (en) * 2010-04-23 2013-02-14 Francois Ravenelle Non-Intravenous Dosage Form Comprising Solid Formulation of Liquid Biologically Active Agent and Uses Thereof
CN102675500B (zh) * 2011-03-07 2015-05-13 深圳英利华生物技术有限公司 利用有机镁试剂制备高分子负载有机锡化合物的方法及应用
US12194113B2 (en) 2018-02-06 2025-01-14 Solventum Intellectual Properties Company Microcapsule with a porous or hollow core and ph-sensitive shell and use thereof

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Also Published As

Publication number Publication date
IL197680A0 (en) 2009-12-24
JP2010504318A (ja) 2010-02-12
CA2699184A1 (en) 2008-03-27
MX2009003092A (es) 2009-05-08
EP2081548A2 (en) 2009-07-29
US20090258071A1 (en) 2009-10-15
BRPI0716890A2 (pt) 2013-10-22
WO2008035229A2 (en) 2008-03-27
AU2007298674A1 (en) 2008-03-27
WO2008035229A3 (en) 2009-08-13

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PA0105 International application

Patent event date: 20090420

Patent event code: PA01051R01D

Comment text: International Patent Application

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