KR20090030385A - 살모넬라 엔테리티디스 감염 박테리오파지로부터 선별된살모넬라 특이적 사멸능을 갖는 신규한 박테리오파지 - Google Patents
살모넬라 엔테리티디스 감염 박테리오파지로부터 선별된살모넬라 특이적 사멸능을 갖는 신규한 박테리오파지 Download PDFInfo
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- KR20090030385A KR20090030385A KR1020070095643A KR20070095643A KR20090030385A KR 20090030385 A KR20090030385 A KR 20090030385A KR 1020070095643 A KR1020070095643 A KR 1020070095643A KR 20070095643 A KR20070095643 A KR 20070095643A KR 20090030385 A KR20090030385 A KR 20090030385A
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- Prior art keywords
- salmonella
- bacteriophage
- sep
- enteritidis
- seq
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Abstract
Description
Primer | Sequence |
M13 정방향 프라이머 | GTCGTGACTGGGAAAACCCTGGCG |
M13 역방향 프라이머 | TCCTGTGTGAAATTGTTATCCGCT |
부분 서열 | 박테리오파지 KS7 과 비교 | 살모넬라 파지 SETP3 과 비교 | 박테리오파지 MB78 과 비교 | |||
Query coverage (%) | Identity (%) | Query coverage (%) | Identity (%) | Query coverage (%) | Identity (%) | |
서열번호 1 | ||||||
서열번호 2 | - | - | - | - | - | - |
서열번호 3 | 20 | 100 | - | - | - | - |
서열번호 4 | - | - | - | - | - | - |
서열번호 5 | - | - | - | - | - | - |
서열번호 6 | 56 | 100 | 56 | 96 | - | - |
서열번호 7 | 53 | 100 | 51 | 90 | 51 | 88 |
서열번호 8 | - | - | - | - | - | - |
서열번호 9 | - | - | - | - | - | - |
서열번호 10 | - | - | - | - | - | - |
서열번호 11 | - | - | - | - | - | - |
서열번호 12 | - | - | - | - | - | - |
서열번호 13 | - | - | - | - | - | - |
서열번호 14 | - | - | - | - | - | - |
서열번호 15 | - | - | - | - | - | - |
서열번호 16 | 42 | 100 | 38 | 90 | 38 | 90 |
서열번호 17 | 100 | 99 | 99 | 94 | - | - |
서열번호 18 | 100 | 100 | 99 | 93 | 99 | 92 |
서열번호 19 | - | - | - | - | - | - |
서열번호 20 | - | - | - | - | - | - |
서열번호 21 | - | - | - | - | - | - |
서열번호 22 | 67 | 100 | 67 | 80 | 67 | 80 |
서열번호 23 | 99 | 99 | - | - | - | - |
서열번호 24 | - | - | - | - | - | - |
서열번호 25 | 100 | 100 | 89 | 85 | 86 | 84 |
구분 | 배양 0시간 | 배양후 10분 | 배양후 60분 |
대조군(무처리) | 0.5 | 0.65 | 1.2 |
실험군 (박테리오파지액 첨가) | 0.5 | 0.1 | 0.05 |
대상 살모넬라 | 대상 살모넬라 수 | 조사결과 | |
용균 활성이 확인된 살모넬라 수 | 용균 활성이 확인되지 않은 살모넬라 수 | ||
살모넬라 엔테리티디스 | 7 | 7 | 0 |
살모넬라 갈리나룸 | 9 | 8 | 1 |
살모넬라 풀오룸 | 9 | 6 | 3 |
살모넬라 티피무륨 | 7 | 6 | 1 |
Claims (10)
- 살모넬라 엔테리티디스(Salmonella enteritidis)를 포함한 살모넬라속균에 대한 특이적 사멸능을 갖는 박테리오파지(Bacteriophage).
- 제1항에 있어서, 상기 살모넬라속균은 살모넬라 엔테리티디스, 살모넬라 갈리나룸(Salmonella gallinarum), 살모넬라 풀오룸(Salmonella pullorum) 또는 살모넬라 티피무륨(Salmonella typhimuriun)인 것을 특징으로 하는 박테리오파지.
- 제1항에 있어서, 상기 박테리오파지는 기탁번호 KCTC 11173BP의 박테리오파지인 것을 특징으로 하는 박테리오파지.
- 제1항에 있어서, 상기 박테리오파지는 서열번호 1 내지 서열번호 25의 부분 유전자 서열로 표시되는 유전체를 갖는 것을 특징으로 하는 박테리오파지.
- 제1항 내지 제3항 중 한 항의 박테리오파지를 유효성분으로 포함하는, 살모넬라 엔테리티디스를 포함한 살모넬라속균 유발성 질환의 예방 또는 치료용 약학적 조성물.
- 제5항에 있어서, 상기 살모넬라 엔테리티디스를 포함한 살모넬라속균 유발성 질환은 식중독, 장염, 살모넬라증, 가금티푸스 또는 급성 균혈증(Bacteremia)인 것을 특징으로 하는 약학적 조성물.
- 제1항 내지 제3항 중 한 항의 박테리오파지를 유효성분으로 포함하는 항생제.
- 제1항 내지 제3항 중 한 항의 박테리오파지를 유효성분으로 포함하는 소독제.
- 제1항 내지 제3항 중 한 항의 박테리오파지를 포함하는 사료첨가제.
- 제1항 내지 제3항 중 한 항의 박테리오파지를 포함하는 음용수.
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WO2011028064A2 (en) * | 2009-09-03 | 2011-03-10 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028061A2 (en) * | 2009-09-03 | 2011-03-10 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028057A2 (en) * | 2009-09-03 | 2011-03-10 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028059A3 (en) * | 2009-09-03 | 2011-07-14 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011155727A2 (ko) * | 2010-06-09 | 2011-12-15 | 주식회사 인트론바이오테크놀로지 | 살모넬라 콜레라수이스 또는 살모넬라 두블린 감염을 방지 및 처치하는 방법 |
US8329165B2 (en) | 2008-06-09 | 2012-12-11 | Intron Biotechnology, Inc. | Composition for the treatment of ballast water containing bacteriophage as an effective component and biological method with the same for removing bacteria present in ballast water |
US20130011369A1 (en) * | 2011-07-05 | 2013-01-10 | Intron Biotechnology, Inc. | Method for Prevention and Treatment of Salmonella Infection |
KR101284719B1 (ko) * | 2011-02-22 | 2013-07-17 | 주식회사한국야쿠르트 | 살모넬라 엔테리티디스에 대한 특이적 사멸능을 가지는 신규한 박테리오파지 에이취와이9001비피 및 이를 유효성분으로 함유하는 제품 |
WO2015160166A1 (ko) * | 2014-04-15 | 2015-10-22 | 씨제이제일제당(주) | 신규 박테리오파지 및 이를 포함하는 조성물 |
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US8329165B2 (en) | 2008-06-09 | 2012-12-11 | Intron Biotechnology, Inc. | Composition for the treatment of ballast water containing bacteriophage as an effective component and biological method with the same for removing bacteria present in ballast water |
WO2011028061A2 (en) * | 2009-09-03 | 2011-03-10 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028057A2 (en) * | 2009-09-03 | 2011-03-10 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028057A3 (en) * | 2009-09-03 | 2011-07-14 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028059A3 (en) * | 2009-09-03 | 2011-07-14 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028064A3 (en) * | 2009-09-03 | 2011-07-14 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
WO2011028061A3 (en) * | 2009-09-03 | 2011-07-14 | Cj Cheiljedang Corporation | Novel bacteriophage and antibacterial composition comprising the same |
CN102596219B (zh) * | 2009-09-03 | 2014-04-30 | Cj第一制糖株式会社 | 噬菌体和包含所述噬菌体的抗菌组合物 |
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CN102596219A (zh) * | 2009-09-03 | 2012-07-18 | Cj第一制糖株式会社 | 新型噬菌体和包含所述噬菌体的抗菌组合物 |
WO2011155727A3 (ko) * | 2010-06-09 | 2012-04-19 | 주식회사 인트론바이오테크놀로지 | 살모넬라 콜레라수이스 또는 살모넬라 두블린 감염을 방지 및 처치하는 방법 |
WO2011155727A2 (ko) * | 2010-06-09 | 2011-12-15 | 주식회사 인트론바이오테크놀로지 | 살모넬라 콜레라수이스 또는 살모넬라 두블린 감염을 방지 및 처치하는 방법 |
KR101284719B1 (ko) * | 2011-02-22 | 2013-07-17 | 주식회사한국야쿠르트 | 살모넬라 엔테리티디스에 대한 특이적 사멸능을 가지는 신규한 박테리오파지 에이취와이9001비피 및 이를 유효성분으로 함유하는 제품 |
US20130011369A1 (en) * | 2011-07-05 | 2013-01-10 | Intron Biotechnology, Inc. | Method for Prevention and Treatment of Salmonella Infection |
US20160053234A1 (en) * | 2011-07-05 | 2016-02-25 | Intron Biotechnology, Inc. | Method for prevention and treatment of salmonella infection |
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WO2015160166A1 (ko) * | 2014-04-15 | 2015-10-22 | 씨제이제일제당(주) | 신규 박테리오파지 및 이를 포함하는 조성물 |
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KR102193477B1 (ko) * | 2019-06-26 | 2020-12-22 | 주식회사 옵티팜 | 신규한 살모넬라 균 특이 박테리오파지 st20 및 이를 포함하는 항균 조성물 |
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