KR20080048527A - 프리온-특이적 펩토이드 시약 - Google Patents

프리온-특이적 펩토이드 시약 Download PDF

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Publication number
KR20080048527A
KR20080048527A KR1020087008427A KR20087008427A KR20080048527A KR 20080048527 A KR20080048527 A KR 20080048527A KR 1020087008427 A KR1020087008427 A KR 1020087008427A KR 20087008427 A KR20087008427 A KR 20087008427A KR 20080048527 A KR20080048527 A KR 20080048527A
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KR
South Korea
Prior art keywords
prion
complex
peptoid
reagent
pathogenic prion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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KR1020087008427A
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English (en)
Korean (ko)
Inventor
데이비드 페레츠
마이클 디. 콘놀리
로날드 주커만
맨 가오
로버트 엠. 쉬미즈
걸리버 티모테오
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20080048527A publication Critical patent/KR20080048527A/ko
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020087008427A 2005-09-09 2006-09-08 프리온-특이적 펩토이드 시약 Abandoned KR20080048527A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US71576105P 2005-09-09 2005-09-09
US60/715,761 2005-09-09
US72668605P 2005-10-14 2005-10-14
US60/726,686 2005-10-14
US75893406P 2006-01-13 2006-01-13
US60/758,934 2006-01-13

Publications (1)

Publication Number Publication Date
KR20080048527A true KR20080048527A (ko) 2008-06-02

Family

ID=37651167

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087008427A Abandoned KR20080048527A (ko) 2005-09-09 2006-09-08 프리온-특이적 펩토이드 시약

Country Status (14)

Country Link
US (2) US7834144B2 (enExample)
EP (2) EP2383281A3 (enExample)
JP (2) JP5209477B2 (enExample)
KR (1) KR20080048527A (enExample)
CN (1) CN101356186A (enExample)
AU (1) AU2006287299B2 (enExample)
BR (1) BRPI0615618A2 (enExample)
CA (1) CA2621767A1 (enExample)
DK (1) DK1931695T3 (enExample)
ES (1) ES2404940T3 (enExample)
IL (1) IL189992A0 (enExample)
NZ (2) NZ566020A (enExample)
WO (1) WO2007030804A1 (enExample)
ZA (1) ZA200802186B (enExample)

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EP2383281A3 (en) 2005-09-09 2012-01-04 Novartis AG Prion-specific peptoid reagents
FR2892820B1 (fr) * 2005-11-03 2008-02-01 Diagast Soc Par Actions Simpli Procede magnetique d'immunodiagnostic pour la mise en evidence de complexe anticorps/antigene, en particulier de groupe sanguin
AU2008218939B2 (en) * 2007-02-23 2014-05-08 The Research Foundation Of State University Of New York RNA targeting compounds and methods for making and using same
US9260476B2 (en) 2007-02-23 2016-02-16 The Research Foundation For The State University Of New York RNA targeting compounds and methods for making and using same
CA2684798A1 (en) * 2007-04-04 2008-10-16 Novartis Ag Prion elisa
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US8445632B2 (en) * 2008-02-08 2013-05-21 The Regents Of The University Of California Selective poly-N-substituted glycine antibiotics
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US8952127B2 (en) 2010-06-04 2015-02-10 The Regents Of The University Of California Peptoids useful for catalyzing the mineralization of calcium carbonate
WO2013043669A1 (en) * 2011-09-21 2013-03-28 The Board Of Regents Of The University Of Texas System Peptoid compositions for the treatment of alzheimer's disease and polyglutamine expansion disorder
US10391068B2 (en) * 2012-08-06 2019-08-27 Trustees Of Boston University Prion protein ligands as therapeutic agents for neurodegenerative disorders
US9764953B2 (en) 2013-03-20 2017-09-19 The Regents Of The University Of California Peptoids useful for the mineralization of apatite
HK1245015A1 (zh) * 2015-03-11 2018-08-24 卢莫斯制药公司 环肌酸及其类似物的合成
EP3370518B1 (en) 2015-10-14 2023-08-23 X-Therma, Inc. Compositions and methods for reducing ice crystal formation
EP3426673B1 (en) 2016-03-09 2021-05-05 Mike-Ann, LLC Peptoid affinity ligands
JP7212373B2 (ja) * 2017-04-12 2023-01-25 エックス－サーマ インコーポレイテッド 新規ペプトイドポリマーおよび使用方法
WO2020123534A1 (en) 2018-12-10 2020-06-18 Provivi, Inc. Synthesis of conjugated diene pheromones and related compounds

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Also Published As

Publication number Publication date
AU2006287299A1 (en) 2007-03-15
NZ566020A (en) 2012-08-31
NZ594844A (en) 2013-04-26
DK1931695T3 (da) 2013-07-01
CN101356186A (zh) 2009-01-28
CA2621767A1 (en) 2007-03-15
IL189992A0 (en) 2008-08-07
EP1931695B1 (en) 2013-04-10
ES2404940T3 (es) 2013-05-29
EP1931695A1 (en) 2008-06-18
JP5209477B2 (ja) 2013-06-12
BRPI0615618A2 (pt) 2011-05-24
JP2009507833A (ja) 2009-02-26
US20070087972A1 (en) 2007-04-19
AU2006287299B2 (en) 2012-08-23
EP2383281A2 (en) 2011-11-02
JP2012162571A (ja) 2012-08-30
EP2383281A3 (en) 2012-01-04
WO2007030804A1 (en) 2007-03-15
US7834144B2 (en) 2010-11-16
US20120027677A1 (en) 2012-02-02
ZA200802186B (en) 2008-12-31

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