AU2006287299B2 - Prion-specific peptoid reagents - Google Patents

Prion-specific peptoid reagents Download PDF

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Publication number
AU2006287299B2
AU2006287299B2 AU2006287299A AU2006287299A AU2006287299B2 AU 2006287299 B2 AU2006287299 B2 AU 2006287299B2 AU 2006287299 A AU2006287299 A AU 2006287299A AU 2006287299 A AU2006287299 A AU 2006287299A AU 2006287299 B2 AU2006287299 B2 AU 2006287299B2
Authority
AU
Australia
Prior art keywords
prion
peptoid
glycine
complex
pathogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006287299A
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English (en)
Other versions
AU2006287299A1 (en
Inventor
Michael D. Connolly
Man Gao
David Peretz
Robert M. Shimizu
Gulliver Timoteo
Ronald Zuckermann
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Novartis AG
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Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2006287299A1 publication Critical patent/AU2006287299A1/en
Application granted granted Critical
Publication of AU2006287299B2 publication Critical patent/AU2006287299B2/en
Priority to AU2012244255A priority Critical patent/AU2012244255A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2006287299A 2005-09-09 2006-09-08 Prion-specific peptoid reagents Ceased AU2006287299B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012244255A AU2012244255A1 (en) 2005-09-09 2012-10-29 Prion-specific peptoid reagents

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US71576105P 2005-09-09 2005-09-09
US60/715,761 2005-09-09
US72668605P 2005-10-14 2005-10-14
US60/726,686 2005-10-14
US75893406P 2006-01-13 2006-01-13
US60/758,934 2006-01-13
PCT/US2006/035226 WO2007030804A1 (en) 2005-09-09 2006-09-08 Prion-specific peptoid reagents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012244255A Division AU2012244255A1 (en) 2005-09-09 2012-10-29 Prion-specific peptoid reagents

Publications (2)

Publication Number Publication Date
AU2006287299A1 AU2006287299A1 (en) 2007-03-15
AU2006287299B2 true AU2006287299B2 (en) 2012-08-23

Family

ID=37651167

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006287299A Ceased AU2006287299B2 (en) 2005-09-09 2006-09-08 Prion-specific peptoid reagents

Country Status (14)

Country Link
US (2) US7834144B2 (enExample)
EP (2) EP2383281A3 (enExample)
JP (2) JP5209477B2 (enExample)
KR (1) KR20080048527A (enExample)
CN (1) CN101356186A (enExample)
AU (1) AU2006287299B2 (enExample)
BR (1) BRPI0615618A2 (enExample)
CA (1) CA2621767A1 (enExample)
DK (1) DK1931695T3 (enExample)
ES (1) ES2404940T3 (enExample)
IL (1) IL189992A0 (enExample)
NZ (2) NZ566020A (enExample)
WO (1) WO2007030804A1 (enExample)
ZA (1) ZA200802186B (enExample)

Families Citing this family (25)

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US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
WO2006076497A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Osplation of pathogenic prions
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
EP2383281A3 (en) 2005-09-09 2012-01-04 Novartis AG Prion-specific peptoid reagents
FR2892820B1 (fr) * 2005-11-03 2008-02-01 Diagast Soc Par Actions Simpli Procede magnetique d'immunodiagnostic pour la mise en evidence de complexe anticorps/antigene, en particulier de groupe sanguin
AU2008218939B2 (en) * 2007-02-23 2014-05-08 The Research Foundation Of State University Of New York RNA targeting compounds and methods for making and using same
US9260476B2 (en) 2007-02-23 2016-02-16 The Research Foundation For The State University Of New York RNA targeting compounds and methods for making and using same
CA2684798A1 (en) * 2007-04-04 2008-10-16 Novartis Ag Prion elisa
JP2010523977A (ja) * 2007-04-04 2010-07-15 ノバルティス アーゲー プリオンアッセイ
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US8445632B2 (en) * 2008-02-08 2013-05-21 The Regents Of The University Of California Selective poly-N-substituted glycine antibiotics
EP2282753A1 (en) * 2008-04-30 2011-02-16 Novartis AG Assay for pathogenic conformers
WO2010017412A1 (en) * 2008-08-06 2010-02-11 The Regents Of The University Of California Novel biomimetic peptoid polymers
US8828413B2 (en) 2009-02-24 2014-09-09 New York University Peptoid oligomers, pharmaceutical compositions and methods of using the same
EP2438444A1 (en) 2009-06-02 2012-04-11 The Board of Regents of The University of Texas System Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
US20130109581A1 (en) * 2009-11-04 2013-05-02 David Peretz Positively charged species as binding reagents in the separation of protein aggregates from monomers
US8952127B2 (en) 2010-06-04 2015-02-10 The Regents Of The University Of California Peptoids useful for catalyzing the mineralization of calcium carbonate
WO2013043669A1 (en) * 2011-09-21 2013-03-28 The Board Of Regents Of The University Of Texas System Peptoid compositions for the treatment of alzheimer's disease and polyglutamine expansion disorder
US10391068B2 (en) * 2012-08-06 2019-08-27 Trustees Of Boston University Prion protein ligands as therapeutic agents for neurodegenerative disorders
US9764953B2 (en) 2013-03-20 2017-09-19 The Regents Of The University Of California Peptoids useful for the mineralization of apatite
HK1245015A1 (zh) * 2015-03-11 2018-08-24 卢莫斯制药公司 环肌酸及其类似物的合成
EP3370518B1 (en) 2015-10-14 2023-08-23 X-Therma, Inc. Compositions and methods for reducing ice crystal formation
EP3426673B1 (en) 2016-03-09 2021-05-05 Mike-Ann, LLC Peptoid affinity ligands
JP7212373B2 (ja) * 2017-04-12 2023-01-25 エックス-サーマ インコーポレイテッド 新規ペプトイドポリマーおよび使用方法
WO2020123534A1 (en) 2018-12-10 2020-06-18 Provivi, Inc. Synthesis of conjugated diene pheromones and related compounds

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Also Published As

Publication number Publication date
AU2006287299A1 (en) 2007-03-15
NZ566020A (en) 2012-08-31
NZ594844A (en) 2013-04-26
DK1931695T3 (da) 2013-07-01
CN101356186A (zh) 2009-01-28
CA2621767A1 (en) 2007-03-15
IL189992A0 (en) 2008-08-07
EP1931695B1 (en) 2013-04-10
ES2404940T3 (es) 2013-05-29
EP1931695A1 (en) 2008-06-18
JP5209477B2 (ja) 2013-06-12
BRPI0615618A2 (pt) 2011-05-24
JP2009507833A (ja) 2009-02-26
US20070087972A1 (en) 2007-04-19
EP2383281A2 (en) 2011-11-02
JP2012162571A (ja) 2012-08-30
EP2383281A3 (en) 2012-01-04
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