KR20080034523A - 항고혈압제와 항혈관형성제의 치료 조합물 - Google Patents

항고혈압제와 항혈관형성제의 치료 조합물 Download PDF

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Publication number
KR20080034523A
KR20080034523A KR1020087007835A KR20087007835A KR20080034523A KR 20080034523 A KR20080034523 A KR 20080034523A KR 1020087007835 A KR1020087007835 A KR 1020087007835A KR 20087007835 A KR20087007835 A KR 20087007835A KR 20080034523 A KR20080034523 A KR 20080034523A
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KR
South Korea
Prior art keywords
alkyl
pat
pharmaceutical composition
pharmaceutically acceptable
alkoxy
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Ceased
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KR1020087007835A
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English (en)
Korean (ko)
Inventor
존 오웬 커윈
도날드 제임스 오길비
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아스트라제네카 아베
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Publication of KR20080034523A publication Critical patent/KR20080034523A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020087007835A 2000-04-05 2001-04-02 항고혈압제와 항혈관형성제의 치료 조합물 Ceased KR20080034523A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0008269.3 2000-04-05
GBGB0008269.3A GB0008269D0 (en) 2000-04-05 2000-04-05 Combination chemotherapy

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020027013170A Division KR100849149B1 (ko) 2000-04-05 2001-04-02 항고혈압제와 항혈관형성제의 치료 조합물

Publications (1)

Publication Number Publication Date
KR20080034523A true KR20080034523A (ko) 2008-04-21

Family

ID=9889176

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020087007835A Ceased KR20080034523A (ko) 2000-04-05 2001-04-02 항고혈압제와 항혈관형성제의 치료 조합물
KR1020027013170A Expired - Fee Related KR100849149B1 (ko) 2000-04-05 2001-04-02 항고혈압제와 항혈관형성제의 치료 조합물

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KR1020027013170A Expired - Fee Related KR100849149B1 (ko) 2000-04-05 2001-04-02 항고혈압제와 항혈관형성제의 치료 조합물

Country Status (29)

Country Link
US (1) US7829573B2 (enExample)
EP (3) EP1790340A3 (enExample)
JP (1) JP2003528917A (enExample)
KR (2) KR20080034523A (enExample)
CN (1) CN1431902A (enExample)
AT (1) ATE355065T1 (enExample)
AU (2) AU2001244386B2 (enExample)
BR (1) BR0109729A (enExample)
CA (1) CA2401854A1 (enExample)
CY (1) CY1107615T1 (enExample)
CZ (1) CZ299410B6 (enExample)
DE (1) DE60126923T2 (enExample)
DK (1) DK1272186T3 (enExample)
EE (1) EE200200578A (enExample)
ES (1) ES2280349T3 (enExample)
GB (1) GB0008269D0 (enExample)
HU (1) HUP0300426A2 (enExample)
IL (1) IL151503A0 (enExample)
IS (2) IS2455B (enExample)
MX (1) MXPA02009743A (enExample)
NO (2) NO323467B1 (enExample)
NZ (2) NZ520938A (enExample)
PL (1) PL357605A1 (enExample)
PT (1) PT1272186E (enExample)
RU (1) RU2002129353A (enExample)
SI (1) SI1272186T1 (enExample)
SK (1) SK14302002A3 (enExample)
WO (1) WO2001074360A1 (enExample)
ZA (1) ZA200206959B (enExample)

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NO20024814L (no) 2002-11-12
DE60126923D1 (de) 2007-04-12
HUP0300426A2 (hu) 2003-06-28
PL357605A1 (en) 2004-07-26
NO20024814D0 (no) 2002-10-04
EP1272186A1 (en) 2003-01-08
CZ299410B6 (cs) 2008-07-16
US7829573B2 (en) 2010-11-09
NO20062050L (no) 2001-10-08
MXPA02009743A (es) 2003-03-27
NZ520938A (en) 2005-08-26
CN1431902A (zh) 2003-07-23
IL151503A0 (en) 2003-04-10
JP2003528917A (ja) 2003-09-30
PT1272186E (pt) 2007-04-30
NO326277B1 (no) 2008-10-27
EP1790340A2 (en) 2007-05-30
SI1272186T1 (sl) 2007-06-30
KR20030007491A (ko) 2003-01-23
RU2002129353A (ru) 2004-03-20
AU2001244386B2 (en) 2005-01-27
EP1658849A3 (en) 2009-02-18
NO323467B1 (no) 2007-05-21
IS8726A (is) 2008-04-16
WO2001074360A1 (en) 2001-10-11
IS2455B (is) 2008-11-15
CA2401854A1 (en) 2001-10-11
CY1107615T1 (el) 2013-03-13
EP1272186B1 (en) 2007-02-28
KR100849149B1 (ko) 2008-07-31
ZA200206959B (en) 2003-12-01
ATE355065T1 (de) 2006-03-15
DK1272186T3 (da) 2007-05-21
BR0109729A (pt) 2003-02-04
DE60126923T2 (de) 2007-10-31
EP1790340A3 (en) 2009-03-18
NZ534455A (en) 2007-01-26
AU4438601A (en) 2001-10-15
EE200200578A (et) 2004-06-15
GB0008269D0 (en) 2000-05-24
EP1658849A2 (en) 2006-05-24
ES2280349T3 (es) 2007-09-16
US20030144298A1 (en) 2003-07-31
IS6557A (is) 2002-09-20

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