SI1272186T1 - Terapevtske kombinacije antihipertenzivnih in antiangiogenskih sredstev - Google Patents

Terapevtske kombinacije antihipertenzivnih in antiangiogenskih sredstev

Info

Publication number
SI1272186T1
SI1272186T1 SI200130715T SI200130715T SI1272186T1 SI 1272186 T1 SI1272186 T1 SI 1272186T1 SI 200130715 T SI200130715 T SI 200130715T SI 200130715 T SI200130715 T SI 200130715T SI 1272186 T1 SI1272186 T1 SI 1272186T1
Authority
SI
Slovenia
Prior art keywords
antihypertensive
agent
therapeutic combinations
antiangiogenic agents
angiogenesis
Prior art date
Application number
SI200130715T
Other languages
English (en)
Inventor
Jon Owen Curwen
Donald James Ogilvie
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SI1272186T1 publication Critical patent/SI1272186T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/556Angiotensin converting enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI200130715T 2000-04-05 2001-04-02 Terapevtske kombinacije antihipertenzivnih in antiangiogenskih sredstev SI1272186T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0008269.3A GB0008269D0 (en) 2000-04-05 2000-04-05 Combination chemotherapy
PCT/GB2001/001522 WO2001074360A1 (en) 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents
EP01917305A EP1272186B1 (en) 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents

Publications (1)

Publication Number Publication Date
SI1272186T1 true SI1272186T1 (sl) 2007-06-30

Family

ID=9889176

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130715T SI1272186T1 (sl) 2000-04-05 2001-04-02 Terapevtske kombinacije antihipertenzivnih in antiangiogenskih sredstev

Country Status (29)

Country Link
US (1) US7829573B2 (sl)
EP (3) EP1658849A3 (sl)
JP (1) JP2003528917A (sl)
KR (2) KR20080034523A (sl)
CN (1) CN1431902A (sl)
AT (1) ATE355065T1 (sl)
AU (2) AU4438601A (sl)
BR (1) BR0109729A (sl)
CA (1) CA2401854A1 (sl)
CY (1) CY1107615T1 (sl)
CZ (1) CZ299410B6 (sl)
DE (1) DE60126923T2 (sl)
DK (1) DK1272186T3 (sl)
EE (1) EE200200578A (sl)
ES (1) ES2280349T3 (sl)
GB (1) GB0008269D0 (sl)
HU (1) HUP0300426A2 (sl)
IL (1) IL151503A0 (sl)
IS (2) IS2455B (sl)
MX (1) MXPA02009743A (sl)
NO (2) NO323467B1 (sl)
NZ (2) NZ534455A (sl)
PL (1) PL357605A1 (sl)
PT (1) PT1272186E (sl)
RU (1) RU2002129353A (sl)
SI (1) SI1272186T1 (sl)
SK (1) SK14302002A3 (sl)
WO (1) WO2001074360A1 (sl)
ZA (1) ZA200206959B (sl)

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GB0424339D0 (en) * 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
WO2007003933A2 (en) 2005-07-06 2007-01-11 Astrazeneca Ab Combination therapy of cancer with azd2171 and gemcitabine
BRPI0619853A2 (pt) 2005-12-15 2016-08-23 Astrazeneca Ab combinação, composição farmacêutica, e, métodos de antagonização da atividade biológica, de tratamento de angiogênese relacionada à doença em um mamífero e de tratamento de câncer em um mamífero
SI1971338T1 (sl) 2005-12-22 2011-06-30 Astrazeneca Ab Kombinacija ZD6474 in pemetrekseda
WO2007071970A2 (en) * 2005-12-22 2007-06-28 Astrazeneca Ab Combination of azd2171 and pemetrexed
EP2066353B1 (en) 2006-09-29 2013-01-02 AstraZeneca AB Combination of zd6474 and bevacizumab for cancer therapy
WO2008125820A1 (en) 2007-04-13 2008-10-23 Astrazeneca Ab Combination therapy comprising azd2171 and azd6244 or mek-inhibitor ii

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MXPA02009743A (es) 2003-03-27
EP1658849A2 (en) 2006-05-24
AU4438601A (en) 2001-10-15
KR20030007491A (ko) 2003-01-23
IS8726A (is) 2008-04-16
IL151503A0 (en) 2003-04-10
CA2401854A1 (en) 2001-10-11
US20030144298A1 (en) 2003-07-31
EE200200578A (et) 2004-06-15
US7829573B2 (en) 2010-11-09
SK14302002A3 (sk) 2003-05-02
PT1272186E (pt) 2007-04-30
DK1272186T3 (da) 2007-05-21
IS2455B (is) 2008-11-15
JP2003528917A (ja) 2003-09-30
EP1272186B1 (en) 2007-02-28
EP1658849A3 (en) 2009-02-18
ATE355065T1 (de) 2006-03-15
GB0008269D0 (en) 2000-05-24
WO2001074360A1 (en) 2001-10-11
RU2002129353A (ru) 2004-03-20
NO323467B1 (no) 2007-05-21
EP1272186A1 (en) 2003-01-08
CN1431902A (zh) 2003-07-23
HUP0300426A2 (hu) 2003-06-28
IS6557A (is) 2002-09-20
CZ299410B6 (cs) 2008-07-16
DE60126923T2 (de) 2007-10-31
EP1790340A3 (en) 2009-03-18
NZ520938A (en) 2005-08-26
KR20080034523A (ko) 2008-04-21
AU2001244386B2 (en) 2005-01-27
DE60126923D1 (de) 2007-04-12
NZ534455A (en) 2007-01-26
ZA200206959B (en) 2003-12-01
NO326277B1 (no) 2008-10-27
KR100849149B1 (ko) 2008-07-31
BR0109729A (pt) 2003-02-04
NO20024814D0 (no) 2002-10-04
NO20062050L (no) 2001-10-08
NO20024814L (no) 2002-11-12
ES2280349T3 (es) 2007-09-16
CY1107615T1 (el) 2013-03-13
EP1790340A2 (en) 2007-05-30
PL357605A1 (en) 2004-07-26

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