KR20060120162A - Ｈｃｖ 치료용 배합물 - Google Patents
Ｈｃｖ 치료용 배합물 Download PDFInfo
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- KR20060120162A KR20060120162A KR1020067010372A KR20067010372A KR20060120162A KR 20060120162 A KR20060120162 A KR 20060120162A KR 1020067010372 A KR1020067010372 A KR 1020067010372A KR 20067010372 A KR20067010372 A KR 20067010372A KR 20060120162 A KR20060120162 A KR 20060120162A
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- Prior art keywords
- inhibitor
- hepatitis
- virus
- cytochrome
- protease
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
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| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
| US7964624B1 (en) | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
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| EP2007381A4 (en) * | 2006-03-06 | 2010-11-17 | Abbott Lab | COMPOSITIONS AND METHODS OF USING RITONAVIR FOR THE TREATMENT OF HEPATITIS C VIRUS |
| JP2009531315A (ja) | 2006-03-16 | 2009-09-03 | バーテックス ファーマシューティカルズ インコーポレイテッド | 重水素化ｃ型肝炎プロテアーゼインヒビター |
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| WO2008106058A2 (en) * | 2007-02-27 | 2008-09-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| JP5393665B2 (ja) * | 2007-07-06 | 2014-01-22 | ギリアード サイエンシーズ， インコーポレイテッド | 治療剤の薬物動態特性の調整剤 |
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| US20090082366A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched telaprevir |
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| WO2009108865A2 (en) * | 2008-02-28 | 2009-09-03 | Abbott Laboratories | Tablets and preparation thereof |
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| WO2010099432A2 (en) * | 2009-02-26 | 2010-09-02 | The Johns Hopkins University | Recognition of cyp2e1 epitopes |
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| US8673954B2 (en) | 2009-02-27 | 2014-03-18 | Enanta Pharmaceuticals, Inc. | Benzimidazole derivatives |
| US9765087B2 (en) | 2009-02-27 | 2017-09-19 | Enanta Pharmaceuticals, Inc. | Benzimidazole derivatives |
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| FR2779653B1 (fr) * | 1998-06-11 | 2002-12-20 | Inst Nat Sante Rech Med | Utilisation de composes modulateurs du proteasome en therapie |
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| US7109172B2 (en) * | 2003-07-18 | 2006-09-19 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease |
| TWI359147B (en) * | 2003-09-05 | 2012-03-01 | Vertex Pharma | Inhibitors of serine proteases, particularly hcv n |
| KR20060130027A (ko) * | 2003-10-10 | 2006-12-18 | 버텍스 파마슈티칼스 인코포레이티드 | 세린 프로테아제, 특히 ｈｃｖ ｎｓ3-ｎｓ4ａ 프로테아제의억제제 |
| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
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| BRPI0415935A (pt) | 2007-01-02 |
| US20060003942A1 (en) | 2006-01-05 |
| CA2543696A1 (en) | 2005-05-12 |
| WO2005042020A3 (en) | 2005-06-23 |
| NO20062428L (no) | 2006-05-29 |
| US20100015090A1 (en) | 2010-01-21 |
| ES2319775T3 (es) | 2009-05-12 |
| PT1677827E (pt) | 2009-03-13 |
| SI1677827T1 (sl) | 2009-06-30 |
| IL175211A0 (en) | 2006-09-05 |
| WO2005042020A2 (en) | 2005-05-12 |
| AU2004285503A1 (en) | 2005-05-12 |
| RU2006118359A (ru) | 2007-12-10 |
| JP2007509950A (ja) | 2007-04-19 |
| PL1677827T3 (pl) | 2009-06-30 |
| MXPA06004723A (es) | 2006-07-05 |
| US20120114604A1 (en) | 2012-05-10 |
| ZA200603863B (en) | 2007-11-28 |
| CN1893978A (zh) | 2007-01-10 |
| DE602004018363D1 (de) | 2009-01-22 |
| ATE416789T1 (de) | 2008-12-15 |
| DK1677827T3 (da) | 2009-03-30 |
| CY1110176T1 (el) | 2015-01-14 |
| EP1677827B1 (en) | 2008-12-10 |
| EP1677827A2 (en) | 2006-07-12 |
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