KR20050057086A - 치료적 처치 방법 - Google Patents

치료적 처치 방법 Download PDF

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Publication number
KR20050057086A
KR20050057086A KR1020057003575A KR20057003575A KR20050057086A KR 20050057086 A KR20050057086 A KR 20050057086A KR 1020057003575 A KR1020057003575 A KR 1020057003575A KR 20057003575 A KR20057003575 A KR 20057003575A KR 20050057086 A KR20050057086 A KR 20050057086A
Authority
KR
South Korea
Prior art keywords
ene
dihydroxy
fluoroandrost
hydroxy
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020057003575A
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English (en)
Korean (ko)
Inventor
크리스토퍼 리딩
클라렌스 엔. 알렘
도미니끄 엘. 아우시
찰스 다우딩
제임스 프린케
메이 리
테오도르 엠. 페이지
리차드 제이. 트라우저
드와이트 알. 스티크니
스티븐 케이. 화이트
Original Assignee
홀리스-에덴 파마슈티칼즈, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 홀리스-에덴 파마슈티칼즈, 인코포레이티드 filed Critical 홀리스-에덴 파마슈티칼즈, 인코포레이티드
Publication of KR20050057086A publication Critical patent/KR20050057086A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020057003575A 2002-08-28 2003-08-28 치료적 처치 방법 Withdrawn KR20050057086A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US40714602P 2002-08-28 2002-08-28
US60/407,146 2002-08-28
US40833202P 2002-09-04 2002-09-04
US60/408,332 2002-09-04
US47925703P 2003-06-17 2003-06-17
US60/479,257 2003-06-17

Publications (1)

Publication Number Publication Date
KR20050057086A true KR20050057086A (ko) 2005-06-16

Family

ID=31982343

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057003575A Withdrawn KR20050057086A (ko) 2002-08-28 2003-08-28 치료적 처치 방법

Country Status (7)

Country Link
US (6) US20040138187A1 (https=)
EP (3) EP2298315A1 (https=)
JP (1) JP2006506445A (https=)
KR (1) KR20050057086A (https=)
AU (1) AU2003278744B2 (https=)
CA (1) CA2496867A1 (https=)
WO (1) WO2004019953A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101250181B1 (ko) * 2006-02-10 2013-04-05 동화약품주식회사 감수에서 분리된 테르페노이드 또는 이를 포함하는감수추출물을 함유하는 골다공증 예방 및 치료용 약학조성물
KR20240133904A (ko) * 2023-02-28 2024-09-05 대한민국(질병관리청 국립보건연구원장) 스테로이드 유도체 계열 화합물 및 이를 유효성분으로 함유하는 항바이러스제

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US20030060425A1 (en) * 1998-11-24 2003-03-27 Ahlem Clarence N. Immune modulation method using steroid compounds
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US20070129282A1 (en) * 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
US20060079492A1 (en) * 1999-10-25 2006-04-13 Ahlem Clarence N Compositions and treatment methods
US7163918B2 (en) 2000-08-22 2007-01-16 New River Pharmaceuticals Inc. Iodothyronine compositions
CA2484963A1 (en) * 2002-05-01 2003-11-13 Arthur Schwartz 7-hydroxy-16a-fluoro-5-androsten-17-ones and 7-hydroxy-16a-fluoro-5-androstan-17-ones and derivatives thereof
US8569275B2 (en) 2002-08-28 2013-10-29 Harbor Therapeutics, Inc. Steroids having 7-oxgen and 17-heteroaryl substitution
US20050101581A1 (en) 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
EP2298315A1 (en) * 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
US7572780B2 (en) 2003-01-21 2009-08-11 Dimera, Incorporated Method and kit for reducing the symptoms of peripheral vascular disease
US20080249129A1 (en) * 2004-04-02 2008-10-09 Whitehead Institute For Biomedical Research Compositions and Methods for Treatment of Protein Misfolding Diseases
US20090162315A1 (en) * 2004-06-29 2009-06-25 Terman David S Enterotoxin gene cluster (egc) superantigens to treat malignant disease
ATE468536T1 (de) * 2004-07-19 2010-06-15 American Diagnostica Inc Verfahren zur messung von adamts13-aktivität auf der blutplättchenoberfläche.
US7270976B2 (en) * 2004-07-19 2007-09-18 American Diagnostica, Inc. Methods for measuring ADAMTS13 activity and protein on platelets and in plasma
US20080138837A1 (en) * 2004-07-19 2008-06-12 Robert Greenfield Methods and kits for detecting and measuring ADAMTS13/FXI complexes
US8865749B2 (en) * 2004-08-01 2014-10-21 Trevor Gordon Marshall Treatment and prevention of Th1 and ‘autoimmune’ diseases effected with antibiotics and/or angiotensin inhibition
EP1795191A4 (en) * 2004-09-21 2007-12-19 Kyowa Hakko Kogyo Kk ORAL PHARMACEUTICAL FOR THE PREVENTION OR TREATMENT OF SKIN DRYNESS
US7910755B2 (en) * 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
US20060073099A1 (en) * 2004-10-01 2006-04-06 Frincke James M Treatment screening methods
KR100766750B1 (ko) * 2004-12-13 2007-10-17 주식회사 엘지생명과학 바이오칩의 제조방법
WO2006102350A1 (en) * 2005-03-23 2006-09-28 Washington University In St. Louis The use of archaea to modulate the nutrient harvesting functions of the gastrointestinal microbiota
US20060281720A1 (en) * 2005-06-08 2006-12-14 Loria Roger M 5-Androstenediol As An Inhibitor of Gliomas
CN101282646B (zh) 2005-07-12 2013-03-27 Dmi生物科学公司 治疗疾病的方法和产品
US20090105202A1 (en) * 2005-10-20 2009-04-23 California Pacific Medical Center Androsterone Derivatives and Method of Use thereof
US20070135504A1 (en) * 2005-12-11 2007-06-14 Marshall Trevor G Method of Treating and/or Preventing Inflammatory Diseases, including many Autoimmune and Neurological diseases, using drugs to modulate the VDR, and/or PPAR, and/or GCR and/or CB1 nuclear and GPCR receptors; in conjunction with antibiotics which target prokaryotic protein translation
WO2007094632A1 (en) * 2006-02-15 2007-08-23 Md Bioalpha Co., Ltd. Method for controlling nad(p)/nad(p)h ratio by oxidoreductase
US8252532B2 (en) * 2006-04-05 2012-08-28 University Of Connecticut Regulators of the non-genomic action of progesterone and methods of use
WO2008039566A2 (en) * 2006-04-22 2008-04-03 Hollis-Eden Pharmaceuticals, Inc. Drugs and uses
US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
US8354396B2 (en) * 2006-11-17 2013-01-15 Harbor Therapeutics, Inc. Drug identification and treatment method
US8486926B2 (en) 2006-11-17 2013-07-16 Harbor Therapeutics, Inc. Steroid tetrol solid state forms
US8217025B2 (en) 2006-11-17 2012-07-10 Harbor Therapeutics, Inc. Drug screening and treatment methods
US20080221074A1 (en) * 2006-11-17 2008-09-11 Jaime Flores-Riveros Drug Screen and Treatment Method
WO2008086452A2 (en) * 2007-01-10 2008-07-17 Columbia University Treatment and prevention of alzheimer's disease
US20080255766A1 (en) * 2007-02-16 2008-10-16 Rules-Based Medicine, Inc. Methods and kits for the diagnosis of sickle cell
WO2009009132A1 (en) * 2007-07-12 2009-01-15 Cougar Biotechnology, Inc. Use of 17alpha-hydroxylase/c17, 20-lyase inhibitors for the treatment of cancer
ITMI20071616A1 (it) 2007-08-03 2009-02-04 Cosmo Spa Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
CA2697160A1 (en) * 2007-08-21 2009-02-26 Harbor Biosciences, Inc. Stabilized therapeutic compositions and formulations
JP2011500856A (ja) * 2007-10-31 2011-01-06 シーアールシー フォー アズマ アンド エアウェイズ エルティーディー 気道組織リモデリングを調節するための方法および組成物
US20090214641A1 (en) * 2008-02-26 2009-08-27 Joar Opheim Sweetened Capsules for Administration
US20100286106A1 (en) * 2008-03-10 2010-11-11 Yigal Gat Methods and apparatus for treating the prostate
WO2009129525A2 (en) * 2008-04-18 2009-10-22 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Antifungal and anti-cariogenic cellobio-oligosaccharides produced by dextransucrase
JP5780521B2 (ja) 2008-05-28 2015-09-16 リベラジェン・バイオファーマ・インコーポレイテッドＲｅｖｅｒａＧｅｎ ＢｉｏＰｈａｒｍａ，Ｉｎｃ． 疾患を治療するための、ＮＦ−κＢの非ホルモン性ステロイド調節因子
ES2523769T3 (es) 2009-06-22 2014-12-01 Ampio Pharmaceuticals, Inc. Procedimiento de tratamiento de enfermedades
SG177302A1 (en) * 2009-06-22 2012-02-28 Dmi Acquisition Corp Methods and products for treatment of diseases
US8811535B2 (en) * 2009-07-17 2014-08-19 Mitre Corporation Time-frequency space constructions of families of signals
WO2011022619A1 (en) * 2009-08-20 2011-02-24 Glaxo Group Limited TREATING INFLAMMATORY DISEASES BY ADMINISTRATION OF REV-ERB α LIGANDS
WO2011032109A1 (en) * 2009-09-11 2011-03-17 Sma Foundation Biomarkers for spinal muscular atrophy
EP2506855A4 (en) * 2009-11-30 2014-07-30 Harbor Biosciences Inc ANTICARCINOMA COMPOUNDS AND SCREENING METHODS
KR20110097497A (ko) * 2010-02-25 2011-08-31 서울대학교산학협력단 전자파 노출을 진단하기 위한 마커 및 이를 포함하는 키트
KR20110097499A (ko) * 2010-02-25 2011-08-31 서울대학교산학협력단 전자파 노출을 진단하기 위한 마커 및 이를 포함하는 키트
KR20110097498A (ko) * 2010-02-25 2011-08-31 서울대학교산학협력단 전자파 노출을 진단하기 위한 마커 및 이를 포함하는 키트
CN103153352B (zh) 2010-08-18 2015-07-15 爱默蕾大学 用于骨化的化合物和组合物以及其相关的方法
CN102079771B (zh) * 2010-12-10 2012-10-03 郑州大学 具有抗肿瘤活性的雌甾氨基酸酯化合物及其合成方法
KR101286743B1 (ko) * 2011-02-18 2013-07-15 충남대학교산학협력단 페노피브레이트를 함유하는 패혈증 예방용 약학 조성물
WO2012115987A2 (en) * 2011-02-21 2012-08-30 The Trustees Of Columbia University In The City Of New York Methods for Treating and Preventing Cardiac Dysfunction in Septic Shock
CN107164330A (zh) * 2011-04-08 2017-09-15 贝勒医学院 使用嵌合细胞因子受体逆转肿瘤微环境的影响
US10478505B2 (en) 2011-09-23 2019-11-19 The Regents Of The University Of California Edible oils to enhance delivery of orally administered steroids
US9675582B2 (en) 2011-10-25 2017-06-13 U.S. Phytotherapy, Inc. Alternative ACT with natural botanical active GRAS ingredients for treatment and prevention of the Zika virus
EP2770985A4 (en) 2011-10-25 2015-01-21 U S Phytotherapy Inc ARTEMISININE AND BERBERINE COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
US9358261B2 (en) 2011-10-25 2016-06-07 U.S. Phytotherapy, Inc. Additional artemisinin and berberine compositions and methods of making
WO2013106672A1 (en) * 2012-01-13 2013-07-18 Tufts Medical Center, Inc. Methods and compositions for the treatment of neurodegenerative disease
SG10201606063RA (en) 2012-01-23 2016-09-29 Sage Therapeutics Inc Neuroactive steroid formulations and methods of treating cns disorders
MX2015002252A (es) 2012-08-21 2015-07-21 Sage Therapeutics Inc Metodos para tratar epilepsia o estado de epilepsia.
EP2904119B1 (en) 2012-10-02 2020-06-17 The General Hospital Corporation d/b/a Massachusetts General Hospital Methods relating to dna-sensing pathway related conditions
DK2925327T3 (da) 2012-11-30 2024-03-25 Univ California Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression
EP2934546A4 (en) 2012-12-19 2016-06-22 Ampio Pharmaceuticals Inc METHOD OF DISEASE TREATMENT
EP2958572B1 (en) 2013-01-03 2019-10-23 Hidros Therapeutics International AB Treatment of hyperhidrosis
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
EP3108879A1 (en) 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
HK1258616A1 (zh) 2016-03-08 2019-11-15 Sage Therapeutics, Inc. 神经活性类固醇、组合物、及其用途
KR101765600B1 (ko) * 2016-04-18 2017-08-07 주식회사 바이오리더스 폴리감마글루탐산의자궁경부상피이형증 치료용도
BR112019001398A2 (pt) 2016-07-29 2019-05-07 Janssen Pharmaceutica Nv métodos para tratamento de câncer de próstata
JP2020536970A (ja) * 2017-10-16 2020-12-17 アミグダラ ニューロサイエンシス インコーポレイテッド 嗜癖を予防するための組み合わせ療法
GB201718667D0 (en) * 2017-11-10 2017-12-27 Mologic Ltd Monitoring inflammation status
IL279348B2 (en) * 2018-06-15 2026-01-01 Reata Pharmaceuticals Inc Decahydro-2h-naphth[1,2-d]imidazole compounds for inhibition of IL-17 and ROR-gamma
US20200108120A1 (en) 2018-10-09 2020-04-09 King Faisal Specialist Hospital & Research Centre Method for treating pulmonary fibrosis using s100a3 protein
WO2020117715A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions
US10857163B1 (en) 2019-09-30 2020-12-08 Athenen Therapeutics, Inc. Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof
CN113318114B (zh) 2020-02-28 2023-02-17 广州市赛普特医药科技股份有限公司 小分子化合物在治疗肺上皮细胞损伤和/或血管内皮细胞损伤介导的疾病中的用途
CN113321695B (zh) * 2021-07-01 2024-01-12 海南师范大学 一种甾体类化合物及其制备方法和应用
JP2025520426A (ja) 2022-06-14 2025-07-03 アミグダラ ニューロサイエンシーズ， インコーポレイテッド Ａｌｄｈ－２阻害化合物及び使用方法
IT202400003238A1 (it) * 2024-02-15 2025-08-15 Ricerfarma Srl Compressa orale mucoadesiva per il trattamento sintomatico della xerostomia, delle afte e delle infiammazioni del cavo orale

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2566336A (en) * 1947-08-28 1951-09-04 Glidden Co Preparation of keto-amine salts in the steroid series and products
US2561378A (en) * 1947-09-11 1951-07-24 Glidden Co 20-dimethylamino-pregnenes and their quaternary halides
US2793217A (en) * 1953-06-27 1957-05-21 Lab Francais Chimiotherapie New derivatives of adrenosterone and a process of making same
US2940991A (en) * 1957-03-01 1960-06-14 Julian Lab Inc Method of epimerizing 11-bromo steroids
US2851454A (en) * 1957-08-02 1958-09-09 Searle & Co 1, 2-epoxy-3, 17-dioxygenated androstane derivatives and their reduction
US2833794A (en) * 1957-12-18 1958-05-06 Searle & Co 3-oxygenated 4-androstene-1, 17-diols and derivatives
US2838544A (en) * 1958-02-19 1958-06-10 Upjohn Co 6alpha-fluoro-16alpha-hydroxy progesterones
US3189597A (en) * 1959-03-04 1965-06-15 Ciba Geigy Corp 3-glycosides of 17-amino-3-hydroxy-5-androstenes
US3080360A (en) * 1960-07-11 1963-03-05 Searle & Co 17alpha-alkyl-17beta-hydroxy-18-norandrost-4-en-3-ones
US3001988A (en) * 1960-07-19 1961-09-26 Searle & Co 3-oxygenated 17beta-aminoalkanamidoandrost-4/5-enes, 5alpha-androstanes corresponding, and intermediates thereto
US3107254A (en) * 1960-10-05 1963-10-15 Upjohn Co 17beta-dialkylamino-17-cyanosteroids and their 17alpha-alkyl, alkylene and alkyne derivatives
US3137710A (en) 1961-03-30 1964-06-16 Ormonoterapia Richter Spa Method for the preparation of primary amines
US3153063A (en) * 1961-05-30 1964-10-13 Ormonoterapia Richter Spa 16-methyl-17-amino-androstane
GB1003681A (en) * 1962-03-09 1965-09-08 May & Baker Ltd Androstane and androstene derivatives
US3155690A (en) * 1962-08-17 1964-11-03 Abbott Lab Nu-substituted 17alpha-aminosteroids
US3187022A (en) * 1964-01-31 1965-06-01 Parke Davis & Co 17beta-amino-17alpha-pregnen-20-one compounds and the production thereof
US3264326A (en) * 1964-04-29 1966-08-02 American Home Prod 17beta-substituted-3alpha-amino-5alpha-androstanes
BE667232A (https=) * 1964-07-22
IL31997A (en) * 1968-05-03 1974-03-14 Lepetit Spa Process for the preparation of pregnano(17alpha,16alpha-d)oxazolines and 16alpha,21-dihydroxy-17alpha-aminopregnanes
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3917829A (en) * 1971-11-08 1975-11-04 Research Corp Novel methods of inhibiting the activity of testosterone 5{60 -reductase
US3989686A (en) * 1972-06-15 1976-11-02 Glaxo Laboratories Limited Anaesthetic steroids of the androstane series and process for preparing same
US3984566A (en) 1974-02-25 1976-10-05 Scott Eugene J Van Method of alleviating the symptoms of dandruff
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4234599A (en) 1978-10-04 1980-11-18 Scott Eugene J Van Treatment of skin keratoses with α-hydroxy acids and related compounds
US4246261A (en) 1979-08-09 1981-01-20 Scott Eugene J Van Additives enhancing topical corticosteroid action
US4424218A (en) * 1979-08-17 1984-01-03 Roussel Uclaf Novel 3 α-amino steroids
MX7065E (es) 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b
US5169857A (en) 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
FR2494697A1 (fr) * 1980-11-21 1982-05-28 Roussel Uclaf Nouveaux derives steroides 3-amines, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
IT1134455B (it) * 1980-11-26 1986-08-13 Lepetit Spa Procedimento per la preparazione di derivati 16alfa-idrossi-17alfa-aminopregnanici
US4330539A (en) * 1981-01-29 1982-05-18 Akzo Nv Novel 17-amino-16-hydroxy steroids of the androstane and oestrane series and derivatives thereof
US4739073A (en) 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
US4908358A (en) * 1987-08-27 1990-03-13 Trustees Of The University Of Pennsylvania Inhibition of immune clearance using progesterone analogues
ATE90355T1 (de) * 1987-10-13 1993-06-15 Nicholas S Bodor Weiche steroide mit anti-entzuendungswirkung.
US4898694A (en) * 1987-11-25 1990-02-06 Schwartz Arthur G 17-Hydroxy-steroids
NO177005C (no) 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
US5262407A (en) 1988-12-16 1993-11-16 L'oreal Use of salicylic derivatives for the treatment of skin aging
US5461042A (en) * 1988-12-30 1995-10-24 Loria; Roger M. Regulation of the immune system
US5077284A (en) * 1988-12-30 1991-12-31 Loria Roger M Use of dehydroepiandrosterone to improve immune response
US5128450A (en) 1989-06-30 1992-07-07 Urdal David L Nonglycosylated human interleukin-3 analog proteins
US5837269A (en) 1989-09-25 1998-11-17 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
CA2066716A1 (en) * 1989-09-25 1991-03-26 Raymond A. Daynes Use of steroid hormones in compositions for inducing t cell lymphokine production
US5753237A (en) 1989-09-25 1998-05-19 University Of Utah Research Foundation Method for augmenting immunological responses
US5641768A (en) * 1989-11-17 1997-06-24 Loria; Roger M. 5-androstene 3β, 17β diol for treatment
US5506223A (en) 1990-08-29 1996-04-09 Humanetics Corporation Δ5-androstenes useful for promoting weight maintenance or weight loss and treatment process
US5641766A (en) * 1990-08-29 1997-06-24 Humanetics Corporation UP-regulation of immune system with Δ 5-Androstenes
US5585371A (en) * 1990-08-29 1996-12-17 Humanetics Corporation Treatment of immune system with Δ5-androstenes
US5080139A (en) 1990-10-31 1992-01-14 Reseal International Limited Partnership Valve assembly with disk-like valve body
US5216015A (en) * 1991-02-05 1993-06-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having hypocholesterolemic properties
US5254343A (en) 1991-03-19 1993-10-19 Bristol-Myers Squibb Company Reduction of cutaneous atrophy
US5206008A (en) * 1991-04-15 1993-04-27 Virginia Commonwealth University Enhancement of immune response
US5834213A (en) 1991-05-02 1998-11-10 Baylor College Of Medicine Screening system and assay for identifying compounds that regulate steroid and orphan receptors mediation of DNA transcription
US6093706A (en) * 1992-03-04 2000-07-25 Bioresponse, L.L.C. Combined dehydroepiandrosterone and retinoid therapy for epithelial disorders
GB2265624B (en) * 1992-03-31 1995-04-19 British Tech Group 17-substituted steroids useful in cancer treatment
US5686438A (en) * 1993-03-09 1997-11-11 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5811418A (en) * 1993-03-09 1998-09-22 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5846963A (en) * 1995-06-07 1998-12-08 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5635496A (en) * 1993-03-09 1997-06-03 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5977095A (en) * 1993-03-09 1999-11-02 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and respiratory distress syndrome
KR960700728A (ko) * 1993-03-09 1996-02-24 토마스 메이져 진행성 조직 괴사, 재관류 손상, 세균 전이 및 성인 호흡 장애 증후군의 예방 방법(Methods for Preventing Progressive Tissue Necrosis, Reperfusion Injury, Bacterial Translocation and Adult Respiratory Distress Syndrome)
US5387583A (en) * 1993-04-20 1995-02-07 Loria; Roger M. Compositions containing corticosteroids or analogues thereof and corticosteroid buffering effective amounts of 5-androstene 3B, 17B or 5-androstene 3B, 7B, 17B triol or analogues thereof
ATE195127T1 (de) 1993-09-29 2000-08-15 Nissin Food Products Ltd In stellung 21 substituierte steroide
US5478566A (en) * 1993-09-29 1995-12-26 Loria; Roger M. Stimulation of cytokine production
JPH07258091A (ja) * 1994-03-17 1995-10-09 Kyowa Hakko Kogyo Co Ltd アトピー性皮膚炎治療剤
US5658744A (en) 1994-07-22 1997-08-19 The United States Of America As Represented By The Department Of Health And Human Services Methods of identifying patients having an altered immune status
US5792757A (en) 1994-08-04 1998-08-11 Pherin Pharmaceuticals 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
US5696127A (en) 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
EP1043325B1 (en) 1994-12-22 2004-06-16 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US20020032160A1 (en) * 1995-02-24 2002-03-14 Nyce Jonathan W. Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels
US5663054A (en) 1995-03-03 1997-09-02 Abbott Laboratories Determination of steroids by competitive immunoassay
DK0838223T3 (da) 1995-06-02 2003-11-17 Shionogi & Co Hjerneødeminhibitor
AU715528B2 (en) 1995-09-08 2000-02-03 Karo Bio Ab Orphan receptor
IL118836A (en) 1996-07-11 2001-01-11 Teva Pharma Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan
US5958892A (en) 1996-07-30 1999-09-28 Board Of Regents, The University Of Texas System 2-methoxyestradiol-induced apoptosis in cancer cells
DE19633376A1 (de) 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue Seco-D-Steroide, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
US5952371A (en) 1996-10-16 1999-09-14 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
US5945412A (en) 1996-12-09 1999-08-31 Merck & Co., Inc. Methods and compositions for preventing and treating bone loss
US5885977A (en) * 1997-01-15 1999-03-23 Humanetics Corporation Use of Δ5 androstenes in the treatment of HIV wasting syndrome
JP3688446B2 (ja) 1997-01-23 2005-08-31 ヒゲタ醤油株式会社 新規テルペン系化合物０４０６ｔｐ−１
US5945410A (en) 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US5935968A (en) 1997-03-17 1999-08-10 Merck & Co., Inc. Methods for treating polycystic ovary syndrome
US5925657A (en) 1997-06-18 1999-07-20 The General Hospital Corporation Use of PPARγ agonists for inhibition of inflammatory cytokine production
US5952319A (en) 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
AU763307B2 (en) * 1998-02-04 2003-07-17 Charlotte-Mecklenburg Hospital Authority Androsterone derivatives for inhibiting DNA binding of AP-1 and airway smooth muscle proliferation
US6380207B2 (en) 1998-02-13 2002-04-30 Abbott Laboratories Glucocortiocoid-selective antiinflammatory agents
US6107034A (en) 1998-03-09 2000-08-22 The Board Of Trustees Of The Leland Stanford Junior University GATA-3 expression in human breast carcinoma
WO1999045930A1 (en) 1998-03-13 1999-09-16 Pharmadigm, Inc. Screening for dhea mimetics using members of the inflammatory cell signalling cascade specifically modulated by dhea as targets
WO1999052532A1 (en) * 1998-04-14 1999-10-21 Pharmadigm, Inc. Method for reducing central nervous system impairment
EP1082113A2 (en) 1998-05-26 2001-03-14 Peter Louis Carlen Compositions and methods for alleviating impaired mental function, memory loss and reducing recovery time in anaesthetized mammals
EP1731157A3 (en) * 1998-06-11 2009-07-15 Endorecherche, Inc. Pharmaceutical compositions and uses for androst-5-ene-3 beta,17 beta-diol
US20070129282A1 (en) 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
OA11716A (en) * 1998-11-24 2005-01-25 Hollis Eden Pharmaceuticals Use of 17-ketosteroid compounds and derivatives, metabolites and precursors thereof in the treatmentof hepatitis C virus and other togaviruses.
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
CA2365081A1 (en) 1999-03-23 2000-09-28 Hollis-Eden Pharmaceuticals, Inc. Immunomodulatory steroids, in particular the hemihydrate of 16.alpha.-bromoepiandrosterone
PT1955700E (pt) 1999-09-30 2011-05-04 Harbor Biosciences Inc Tratamento terap?utico de doen?as associadas ao receptor de androg?nios
CA2388939C (en) * 1999-10-25 2009-06-09 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatments for blood cell deficiencies
US6348489B1 (en) 2000-04-11 2002-02-19 Daiichi Pharmaceutical Co., Ltd. Method of treating traumatic brain injury and other neuronal disorders
IL135707A0 (en) * 2000-04-17 2001-05-20 Yissum Res Dev Co 19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them
GB2363984A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone
CA2424581A1 (en) * 2000-10-06 2002-04-11 Aeson Therapeutics Inc. Compounds useful for treating hypertriglyceridemia
WO2002069977A1 (en) * 2001-03-01 2002-09-12 Hollis-Eden Pharmaceuticals, Inc. Use of certain steroids for treatment of blood cell deficiencies
US6465446B1 (en) * 2001-03-12 2002-10-15 John C. Dykstra Treatment of dermatitis by the topical application of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof
AU2002303425A1 (en) * 2001-04-24 2002-11-05 Epigenesis Pharmaceuticals, Inc. Composition, formulations and kit for treatment of respiratory and lung disease with non-glucocorticoid steroids and/or ubiquinone and a bronchodilating agent
AU2002303427A1 (en) * 2001-04-24 2002-11-05 East Carolina University Compositions and formulations with a non-glucocorticoid steroid and/or a ubiquinone and kit for treatment of respiratory and lung disease
EP1310258A1 (en) * 2001-11-08 2003-05-14 Etienne-Emile Baulieu Enantiomers of steroids for the enhancement of memory and cognitive function
EP1553954A4 (en) * 2002-06-17 2009-12-23 Epigenesis Pharmaceuticals Llc DIHYDRATE DEHYDROEPIANDROSTERONE AND METHOD FOR THE TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE LUNG DISEASE, COMPOSITIONS THEREOF
US20050101581A1 (en) * 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
EP2298315A1 (en) * 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
CA2522784C (en) 2003-04-01 2012-06-19 Hollis-Eden Pharmaceuticals, Inc. Antiandrogens with marginal agonist activity and methods of use
US7910755B2 (en) 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
US20060073099A1 (en) 2004-10-01 2006-04-06 Frincke James M Treatment screening methods
US20080065873A1 (en) * 2006-09-11 2008-03-13 Ronald Hall Dynamic livelock resolution with variable delay memory access queue
KR20080095683A (ko) * 2007-04-25 2008-10-29 삼성전자주식회사 상변화 메모리 소자 및 그 형성 방법

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* Cited by examiner, † Cited by third party
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KR101250181B1 (ko) * 2006-02-10 2013-04-05 동화약품주식회사 감수에서 분리된 테르페노이드 또는 이를 포함하는감수추출물을 함유하는 골다공증 예방 및 치료용 약학조성물
KR20240133904A (ko) * 2023-02-28 2024-09-05 대한민국(질병관리청 국립보건연구원장) 스테로이드 유도체 계열 화합물 및 이를 유효성분으로 함유하는 항바이러스제

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